Genular: Defining Cellular Identity and Function

Details for: Cst3

Gene ID: 13010

Symbol: Cst3

Ensembl ID: ENSMUSG00000027447

Description: cystatin C

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Amyloid-beta binding
(GO:0001540)
Axon
(GO:0030424)
Basement membrane
(GO:0005604)
Cell projection
(GO:0042995)
Cellular response to oxidative stress
(GO:0034599)
Collagen-containing extracellular matrix
(GO:0062023)
Contractile fiber
(GO:0043292)
Cysteine-type endopeptidase inhibitor activity
(GO:0004869)
Cytoplasm
(GO:0005737)
Defense response
(GO:0006952)
Endopeptidase inhibitor activity
(GO:0004866)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Multivesicular body
(GO:0005771)
Negative regulation of blood vessel remodeling
(GO:0060313)
Negative regulation of collagen catabolic process
(GO:0010711)
Negative regulation of cysteine-type endopeptidase activity
(GO:2000117)
Negative regulation of elastin catabolic process
(GO:0060311)
Negative regulation of extracellular matrix disassembly
(GO:0010716)
Negative regulation of peptidase activity
(GO:0010466)
Negative regulation of proteolysis
(GO:0045861)
Neuronal cell body
(GO:0043025)
Nuclear membrane
(GO:0031965)
Peptidase inhibitor activity
(GO:0030414)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna replication
(GO:0045740)
Protease binding
(GO:0002020)
Regulation of tissue remodeling
(GO:0034103)
Supramolecular fiber organization
(GO:0097435)
Vesicle
(GO:0031982)

Other Information

Proteins

Cystatin-C

Genular Protein ID: 3368159740

Symbol: CYTC_MOUSE

Name: Cystatin-C

UniProtKB Accession Codes:

P21460 Q544Y0

Database IDs:

Citations:

PubMed ID: 2241983

Title: Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells.

PubMed ID: 2241983

DOI: 10.1016/0006-291x(90)90767-h

PubMed ID: 7835704

Title: Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3).

PubMed ID: 7835704

DOI: 10.1016/0378-1119(94)00728-b

PubMed ID: 11471062

Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.

PubMed ID: 11471062

DOI: 10.1007/s00335-001-1001-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 140
Mass: 15531
Checksum: 3A563406DD58D0F5
Sequence:

MASPLRSLLF LLAVLAVAWA ATPKQGPRML GAPEEADANE EGVRRALDFA VSEYNKGSND 
AYHSRAIQVV RARKQLVAGV NYFLDVEMGR TTCTKSQTNL TDCPFHDQPH LMRKALCSFQ 
IYSVPWKGTH SLTKFSCKNA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cst3

Associated with

Other Information

Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells. PubMed ID: 2241983

Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3). PubMed ID: 7835704

High-throughput sequence identification of gene coding variants within alcohol-related QTLs. PubMed ID: 11471062

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334