Details for: COL11A2

Gene ID: 1302

Symbol: COL11A2

Ensembl ID: ENSG00000204248

Description: collagen type XI alpha 2 chain

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.62
    Marker Score: 1174
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.18
    Marker Score: 4355
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.16
    Marker Score: 7685
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.08
    Marker Score: 686
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.99
    Marker Score: 672.5
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 511
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 464
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30409
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2413
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 376
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5354
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.94
    Marker Score: 388
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2740
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 327
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.87
    Marker Score: 1808
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5290
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.87
    Marker Score: 398
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.82
    Marker Score: 628
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1268
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 710
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.71
    Marker Score: 2966
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.68
    Marker Score: 365.5
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.58
    Marker Score: 464
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.58
    Marker Score: 370
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.55
    Marker Score: 173
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 0.48
    Marker Score: 218
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.47
    Marker Score: 132
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.46
    Marker Score: 122
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.44
    Marker Score: 181
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.42
    Marker Score: 942
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.38
    Marker Score: 219
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.29
    Marker Score: 152
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.27
    Marker Score: 2343
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.26
    Marker Score: 89
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.25
    Marker Score: 309
  • Cell Name: gut endothelial cell (CL0000131)
    Fold Change: 0.25
    Marker Score: 88
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.24
    Marker Score: 77.5
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.24
    Marker Score: 77
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.24
    Marker Score: 92
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.22
    Marker Score: 346
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.22
    Marker Score: 63
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.22
    Marker Score: 518
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.22
    Marker Score: 2053
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 73
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 0.2
    Marker Score: 52
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2
    Marker Score: 12473
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.2
    Marker Score: 63
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.2
    Marker Score: 7239
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.19
    Marker Score: 325
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.19
    Marker Score: 98
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.18
    Marker Score: 1730
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.18
    Marker Score: 310
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.18
    Marker Score: 123
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.17
    Marker Score: 6633
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.17
    Marker Score: 1294
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.17
    Marker Score: 43
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.17
    Marker Score: 685
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.15
    Marker Score: 72
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.15
    Marker Score: 571
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.15
    Marker Score: 64
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.15
    Marker Score: 224
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.14
    Marker Score: 2869
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.14
    Marker Score: 2077
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.13
    Marker Score: 47
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.13
    Marker Score: 383
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.13
    Marker Score: 188
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.13
    Marker Score: 34
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.12
    Marker Score: 498
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.12
    Marker Score: 30
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.12
    Marker Score: 67
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.11
    Marker Score: 48
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.11
    Marker Score: 681
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 0.11
    Marker Score: 32
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.11
    Marker Score: 33
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.11
    Marker Score: 154
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.11
    Marker Score: 97
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.11
    Marker Score: 79
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: 0.11
    Marker Score: 31
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.11
    Marker Score: 103
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1
    Marker Score: 39
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.1
    Marker Score: 46
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.1
    Marker Score: 240
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.1
    Marker Score: 157
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.09
    Marker Score: 105
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.09
    Marker Score: 94
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.09
    Marker Score: 417
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.09
    Marker Score: 36
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.09
    Marker Score: 58
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.08
    Marker Score: 1773
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.08
    Marker Score: 37
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.07
    Marker Score: 31
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.07
    Marker Score: 207
  • Cell Name: tendon cell (CL0000388)
    Fold Change: 0.07
    Marker Score: 18
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.07
    Marker Score: 48
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.07
    Marker Score: 70
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.07
    Marker Score: 40
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.07
    Marker Score: 39
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.07
    Marker Score: 50
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.07
    Marker Score: 66

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Other Information

**Key characteristics:** * Type: Collagen type XI alpha 2 chain * Ensembl ID: ENSG00000204248 * Protein length: 136 amino acids * Expression: Significantly expressed in various cell types, including colon goblet cell, cortical thymic epithelial cell, goblet cell, granulocyte monocyte progenitor cell, intestinal crypt stem cell of small intestine, tuft cell of colon, BEST4+ intestinal epithelial cell **Pathways and functions:** * Assembly of collagen fibrils and other multimeric structures * Collagen biosynthesis and modifying enzymes * Collagen chain trimerization * Collagen degradation * Extracellular matrix organization * Extracellular matrix structural constituent conferring tensile strength * Heparin binding * Met activates ptk2 signaling * Met promotes cell motility * Non-integrin membrane-ECM interactions * Protein-macromolecule adaptor activity * Protein binding * Signaling by met * Signaling by receptor tyrosine kinases * Signal transduction **Clinical significance:** * Mutations in COL11A2 have been linked to various human diseases, including osteoporosis, osteoarthritis, and cancer. * COL11A2 inhibitors are being investigated as potential therapeutic agents for these diseases.

Genular Protein ID: 2104372708

Symbol: COBA2_HUMAN

Name: Collagen alpha-2(XI) chain

UniProtKB Accession Codes:

P13942 A6NLX2 E7ER90 Q07751 Q13271 Q13272 Q13273 Q5JP94 Q5SUI8 Q7Z6C3 Q99866 Q9UIP9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 18 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MIM 11 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 5 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 9 RNAct 1 Reactome 6 RefSeq 4 SAM 1 SIGNOR 1 SMART 3 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7559422

Title: The human COL11A2 gene structure indicates that the gene has not evolved with the genes for the major fibrillar collagens.

PubMed ID: 7559422

DOI: 10.1074/jbc.270.39.22873

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8838804

Title: The human alpha 2(XI) collagen gene (COL11A2): completion of coding information, identification of the promoter sequence, and precise localization within the major histocompatibility complex reveal overlap with the KE5 gene.

PubMed ID: 8838804

DOI: 10.1006/geno.1996.0135

PubMed ID: 8325374

Title: Molecular cloning of PARP (proline/arginine-rich protein) from human cartilage and subsequent demonstration that PARP is a fragment of the NH2-terminal domain of the collagen alpha 2(XI) chain.

PubMed ID: 8325374

DOI: 10.1016/0014-5793(93)81753-m

PubMed ID: 2760050

Title: The human alpha 2(XI) collagen (COL11A2) chain. Molecular cloning of cDNA and genomic DNA reveals characteristics of a fibrillar collagen with differences in genomic organization.

PubMed ID: 2760050

DOI: 10.1016/s0021-9258(18)80086-2

PubMed ID: 7721876

Title: Alternative mRNA processing occurs in the variable region of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains.

PubMed ID: 7721876

DOI: 10.1074/jbc.270.16.9486

PubMed ID: 10677296

Title: Autosomal recessive disorder otospondylomegaepiphyseal dysplasia is associated with loss-of-function mutations in the COL11A2 gene.

PubMed ID: 10677296

DOI: 10.1086/302750

PubMed ID: 9101290

Title: Mutations in fibrillar collagens (types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of diseases of bone, cartilage, and blood vessels.

PubMed ID: 9101290

DOI: 10.1002/(sici)1098-1004(1997)9:4<300::aid-humu2>3.0.co;2-9

PubMed ID: 22246659

Title: Dominant and recessive forms of fibrochondrogenesis resulting from mutations at a second locus, COL11A2.

PubMed ID: 22246659

DOI: 10.1002/ajmg.a.34406

PubMed ID: 7859284

Title: Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus.

PubMed ID: 7859284

DOI: 10.1016/0092-8674(95)90493-x

PubMed ID: 9585596

Title: Genetic mapping of ossification of the posterior longitudinal ligament of the spine.

PubMed ID: 9585596

DOI: 10.1086/301868

PubMed ID: 9805126

Title: Heterozygous glycine substitution in the COL11A2 gene in the original patient with the Weissenbacher-Zweymueller syndrome demonstrates its identity with heterozygous OSMED (nonocular Stickler syndrome).

PubMed ID: 9805126

DOI: 10.1002/(sici)1096-8628(19981102)80:2<115::aid-ajmg5>3.0.co;2-o

PubMed ID: 9506662

Title: Stickler syndrome without eye involvement is caused by mutations in COL11A2, the gene encoding the alpha-2(XI) chain of type XI collagen.

PubMed ID: 9506662

DOI: 10.1016/s0022-3476(98)70466-4

PubMed ID: 10581026

Title: Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13).

PubMed ID: 10581026

DOI: 10.1038/70516

PubMed ID: 16033917

Title: Mutation of COL11A2 causes autosomal recessive non-syndromic hearing loss at the DFNB53 locus.

PubMed ID: 16033917

DOI: 10.1136/jmg.2005.032615

PubMed ID: 22938506

Title: Targeted massive parallel sequencing: the effective detection of novel causative mutations associated with hearing loss in small families.

PubMed ID: 22938506

DOI: 10.1186/1750-1172-7-60

PubMed ID: 25633957

Title: Novel mutations confirm that COL11A2 is responsible for autosomal recessive non-syndromic hearing loss DFNB53.

PubMed ID: 25633957

DOI: 10.1007/s00438-015-0995-9

Sequence Information:

  • Length: 1736
  • Mass: 171791
  • Checksum: D687B7AAD6A7774C
  • Sequence:
    • MERCSRCHRL LLLLPLVLGL SAAPGWAGAP PVDVLRALRF PSLPDGVRRA KGICPADVAY 
RVARPAQLSA PTRQLFPGGF PKDFSLLTVV RTRPGLQAPL LTLYSAQGVR QLGLELGRPV 
RFLYEDQTGR PQPPSQPVFR GLSLADGKWH RVAVAVKGQS VTLIVDCKKR VTRPLPRSAR 
PVLDTHGVII FGARILDEEV FEGDVQELAI VPGVQAAYES CEQKELECEG GQRERPQNQQ 
PHRAQRSPQQ QPSRLHRPQN QEPQSQPTES LYYDYEPPYY DVMTTGTTPD YQDPTPGEEE 
EILESSLLPP LEEEQTDLQV PPTADRFQAE EYGEGGTDPP EGPYDYTYGY GDDYREETEL 
GPALSAETAH SGAAAHGPRG LKGEKGEPAV LEPGMLVEGP PGPEGPAGLI GPPGIQGNPG 
PVGDPGERGP PGRAGLPGSD GAPGPPGTSL MLPFRFGSGG GDKGPVVAAQ EAQAQAILQQ 
ARLALRGPPG PMGYTGRPGP LGQPGSPGLK GESGDLGPQG PRGPQGLTGP PGKAGRRGRA 
GADGARGMPG DPGVKGDRGF DGLPGLPGEK GHRGDTGAQG LPGPPGEDGE RGDDGEIGPR 
GLPGESGPRG LLGPKGPPGI PGPPGVRGMD GPQGPKGSLG PQGEPGPPGQ QGTPGTQGLP 
GPQGAIGPHG EKGPQGKPGL PGMPGSDGPP GHPGKEGPPG TKGNQGPSGP QGPLGYPGPR 
GVKGVDGIRG LKGHKGEKGE DGFPGFKGDI GVKGDRGEVG VPGSRGEDGP EGPKGRTGPT 
GDPGPPGLMG EKGKLGVPGL PGYPGRQGPK GSLGFPGFPG ASGEKGARGL SGKSGPRGER 
GPTGPRGQRG PRGATGKSGA KGTSGGDGPH GPPGERGLPG PQGPNGFPGP KGPLGPPGKD 
GLPGHPGQRG EVGFQGKTGP PGPPGVVGPQ GAAGETGPMG ERGHPGPPGP PGEQGLPGTA 
GKEGTKGDPG PPGAPGKDGP AGLRGFPGER GLPGTAGGPG LKGNEGPSGP PGPAGSPGER 
GAAGSGGPIG PPGRPGPQGP PGAAGEKGVP GEKGPIGPTG RDGVQGPVGL PGPAGPPGVA 
GEDGDKGEVG DPGQKGTKGN KGEHGPPGPP GPIGPVGQPG AAGADGEPGA RGPQGHFGAK 
GDEGTRGFNG PPGPIGLQGL PGPSGEKGET GDVGPMGPPG PPGPRGPAGP NGADGPQGPP 
GGVGNLGPPG EKGEPGESGS PGIQGEPGVK GPRGERGEKG ESGQPGEPGP PGPKGPTGDD 
GPKGNPGPVG FPGDPGPPGE GGPRGQDGAK GDRGEDGEPG QPGSPGPTGE NGPPGPLGKR 
GPAGSPGSEG RQGGKGAKGD PGAIGAPGKT GPVGPAGPAG KPGPDGLRGL PGSVGQQGRP 
GATGQAGPPG PVGPPGLPGL RGDAGAKGEK GHPGLIGLIG PPGEQGEKGD RGLPGPQGSP 
GQKGEMGIPG ASGPIGPGGP PGLPGPAGPK GAKGATGPGG PKGEKGVQGP PGHPGPPGEV 
IQPLPIQMPK KTRRSVDGSR LMQEDEAIPT GGAPGSPGGL EEIFGSLDSL REEIEQMRRP 
TGTQDSPART CQDLKLCHPE LPDGEYWVDP NQGCARDAFR VFCNFTAGGE TCVTPRDDVT 
QFSYVDSEGS PVGVVQLTFL RLLSVSAHQD VSYPCSGAAR DGPLRLRGAN EDELSPETSP 
YVKEFRDGCQ TQQGRTVLEV RTPVLEQLPV LDASFSDLGA PPRRGGVLLG PVCFMG

Genular Protein ID: 3046167125

Symbol: Q4VXY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q4VXY6

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 6 GO 4 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 1650
  • Mass: 162185
  • Checksum: 35531E80812CA213
  • Sequence:
    • MERCSRCHRL LLLLPLVLGL SAAPGWAGAP PVDVLRALRF PSLPDGVRRA KGICPADVAY 
RVARPAQLSA PTRQLFPGGF PKDFSLLTVV RTRPGLQAPL LTLYSAQGVR QLGLELGRPV 
RFLYEDQTGR PQPPSQPVFR GLSLADGKWH RVAVAVKGQS VTLIVDCKKR VTRPLPRSAR 
PVLDTHGVII FGARILDEEV FEGDVQELAI VPGVQAAYES CEQKELECEG GQRERPQNQQ 
PHRAQRSPQQ QPSRLHRPQN QEPQSQDPTP GEEEEILESS LLPPLEEAAH GPRGLKGEKG 
EPAVLEPGML VEGPPGPEGP AGLIGPPGIQ GNPGPVGDPG ERGPPGRAGL PGSDGAPGPP 
GTSLMLPFRF GSGGGDKGPV VAAQEAQAQA ILQQARLALR GPPGPMGYTG RPGPLGQPGS 
PGLKGESGDL GPQGPRGPQG LTGPPGKAGR RGRAGADGAR GMPGDPGVKG DRGFDGLPGL 
PGEKGHRGDT GAQGLPGPPG EDGERGDDGE IGPRGLPGES GPRGLLGPKG PPGIPGPPGV 
RGMDGPQGPK GSLGPQGEPG PPGQQGTPGT QGLPGPQGAI GPHGEKGPQG KPGLPGMPGS 
DGPPGHPGKE GPPGTKGNQG PSGPQGPLGY PGPRGVKGVD GIRGLKGHKG EKGEDGFPGF 
KGDIGVKGDR GEVGVPGSRG EDGPEGPKGR TGPTGDPGPP GLMGEKGKLG VPGLPGYPGR 
QGPKGSLGFP GFPGASGEKG ARGLSGKSGP RGERGPTGPR GQRGPRGATG KSGAKGTSGG 
DGPHGPPGER GLPGPQGPNG FPGPKGPPGP PGKDGLPGHP GQRGEVGFQG KTGPPGPPGV 
VGPQGAAGET GPMGERGHPG PPGPPGEQGL PGTAGKEGTK GDPGPPGAPG KDGPAGLRGF 
PGERGLPGTA GGPGLKGNEG PSGPPGPAGS PGERGAAGSG GPIGPPGRPG PQGPPGAAGE 
KGVPGEKGPI GPTGRDGVQG PVGLPGPAGP PGVAGEDGDK GEVGDPGQKG TKGNKGEHGP 
PGPPGPIGPV GQPGAAGADG EPGARGPQGH FGAKGDEGTR GFNGPPGPIG LQGLPGPSGE 
KGETGDVGPM GPPGPPGPRG PAGPNGADGP QGPPGGVGNL GPPGEKGEPG ESGSPGIQGE 
PGVKGPRGER GEKGESGQPG EPGPPGPKGP TGDDGPKGNP GPVGFPGDPG PPGEGGPRGQ 
DGAKGDRGED GEPGQPGSPG PTGENGPPGP LGKRGPAGSP GSEGRQGGKG AKGDPGAIGA 
PGKTGPVGPA GPAGKPGPDG LRGLPGSVGQ QGRPGATGQA GPPGPVGPPG LPGLRGDAGA 
KGEKGHPGLI GLIGPPGEQG EKGDRGLPGP QGSPGQKGEM GIPGASGPIG PGGPPGLPGP 
AGPKGAKGAT GPGGPKGEKG VQGPPGHPGP PGEVIQPLPI QMPKKTRRSV DGSRLMQEDE 
AIPTGGAPGS PGGLEEIFGS LDSLREEIEQ MRRPTGTQDS PARTCQDLKL CHPELPDGEY 
WVDPNQGCAR DAFRVFCNFT AGGETCVTPR DDVTQFSYVD SEGSPVGVVQ LTFLRLLSVS 
AHQDVSYPCS GAARDGPLRL RGANEDELSP ETSPYVKEFR DGCQTQQGRT VLEVRTPVLE 
QLPVLDASFS DLGAPPRRGG VLLGPVCFMG

Genular Protein ID: 316674255

Symbol: A0A0C4DFS1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFS1

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 10 Ensembl 4 GO 9 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 5 KEGG 1 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 RefSeq 2 SAM 2 SMART 3 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 1736
  • Mass: 171775
  • Checksum: FD189666C51EBA60
  • Sequence:
    • MERCSRCHRL LLLLPLVLGL SAAPGWAGAP PVDVLRALRF PSLPDGVRRA KGICPADVAY 
RVARPAQLSA PTRQLFPGGF PKDFSLLTVV RTRPGLQAPL LTLYSAQGVR QLGLELGRPV 
RFLYEDQTGR PQPPSQPVFR GLSLADGKWH RVAVAVKGQS VTLIVDCKKR VTRPLPRSAR 
PVLDTHGVII FGARILDEEV FEGDVQELAI VPGVQAAYES CEQKELECEG GQRERPQNQQ 
PHRAQRSPQQ QPSRLHRPQN QEPQSQPTES LYYDYEPPYY DVMTTGTTPD YQDPTPGEEE 
EILESSLLPP LEEEQTDLQV PPTADRFQAE EYGEGGTDPP EGPYDYTYGY GDDYREETEL 
GPALSAETAH SGAAAHGPRG LKGEKGEPAV LEPGMLVEGP PGPEGPAGLI GPPGIQGNPG 
PVGDPGERGP PGRAGLPGSD GAPGPPGTSL MLPFRFGSGG GDKGPVVAAQ EAQAQAILQQ 
ARLALRGPPG PMGYTGRPGP LGQPGSPGLK GESGDLGPQG PRGPQGLTGP PGKAGRRGRA 
GADGARGMPG DPGVKGDRGF DGLPGLPGEK GHRGDTGAQG LPGPPGEDGE RGDDGEIGPR 
GLPGESGPRG LLGPKGPPGI PGPPGVRGMD GPQGPKGSLG PQGEPGPPGQ QGTPGTQGLP 
GPQGAIGPHG EKGPQGKPGL PGMPGSDGPP GHPGKEGPPG TKGNQGPSGP QGPLGYPGPR 
GVKGVDGIRG LKGHKGEKGE DGFPGFKGDI GVKGDRGEVG VPGSRGEDGP EGPKGRTGPT 
GDPGPPGLMG EKGKLGVPGL PGYPGRQGPK GSLGFPGFPG ASGEKGARGL SGKSGPRGER 
GPTGPRGQRG PRGATGKSGA KGTSGGDGPH GPPGERGLPG PQGPNGFPGP KGPPGPPGKD 
GLPGHPGQRG EVGFQGKTGP PGPPGVVGPQ GAAGETGPMG ERGHPGPPGP PGEQGLPGTA 
GKEGTKGDPG PPGAPGKDGP AGLRGFPGER GLPGTAGGPG LKGNEGPSGP PGPAGSPGER 
GAAGSGGPIG PPGRPGPQGP PGAAGEKGVP GEKGPIGPTG RDGVQGPVGL PGPAGPPGVA 
GEDGDKGEVG DPGQKGTKGN KGEHGPPGPP GPIGPVGQPG AAGADGEPGA RGPQGHFGAK 
GDEGTRGFNG PPGPIGLQGL PGPSGEKGET GDVGPMGPPG PPGPRGPAGP NGADGPQGPP 
GGVGNLGPPG EKGEPGESGS PGIQGEPGVK GPRGERGEKG ESGQPGEPGP PGPKGPTGDD 
GPKGNPGPVG FPGDPGPPGE GGPRGQDGAK GDRGEDGEPG QPGSPGPTGE NGPPGPLGKR 
GPAGSPGSEG RQGGKGAKGD PGAIGAPGKT GPVGPAGPAG KPGPDGLRGL PGSVGQQGRP 
GATGQAGPPG PVGPPGLPGL RGDAGAKGEK GHPGLIGLIG PPGEQGEKGD RGLPGPQGSP 
GQKGEMGIPG ASGPIGPGGP PGLPGPAGPK GAKGATGPGG PKGEKGVQGP PGHPGPPGEV 
IQPLPIQMPK KTRRSVDGSR LMQEDEAIPT GGAPGSPGGL EEIFGSLDSL REEIEQMRRP 
TGTQDSPART CQDLKLCHPE LPDGEYWVDP NQGCARDAFR VFCNFTAGGE TCVTPRDDVT 
QFSYVDSEGS PVGVVQLTFL RLLSVSAHQD VSYPCSGAAR DGPLRLRGAN EDELSPETSP 
YVKEFRDGCQ TQQGRTVLEV RTPVLEQLPV LDASFSDLGA PPRRGGVLLG PVCFMG

Genular Protein ID: 910218105

Symbol: A0A0G2JL78_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0G2JL78

Database IDs:

ARBA 6 CDD 1 CTD 1 EMBL 6 Ensembl 4 GO 3 Gene3D 2 HGNC 1 InterPro 5 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 1629
  • Mass: 159879
  • Checksum: B5967544D70A0E03
  • Sequence:
    • MERCSRCHRL LLLLPLVLGL SAAPGWAGAP PVDVLRALRF PSLPDGVRRA KGICPADVAY 
RVARPAQLSA PTRQLFPGGF PKDFSLLTVV RTRPGLQAPL LTLYSAQGVR QLGLELGRPV 
RFLYEDQTGR PQPPSQPVFR GLSLADGKWH RVAVAVKGQS VTLIVDCKKR VTRPLPRSAR 
PVLDTHGVII FGARILDEEV FEGDVQELAI VPGVQAAYES CEQKELECEG GQRERPQNQQ 
PHRAQRSPQQ QPSRLHRPQN QEPQSQAAHG PRGLKGEKGE PAVLEPGMLV EGPPGPEGPA 
GLIGPPGIQG NPGPVGDPGE RGPPGRAGLP GSDGAPGPPG TSLMLPFRFG SGGGDKGPVV 
AAQEAQAQAI LQQARLALRG PPGPMGYTGR PGPLGQPGSP GLKGESGDLG PQGPRGPQGL 
TGPPGKAGRR GRAGADGARG MPGDPGVKGD RGFDGLPGLP GEKGHRGDTG AQGLPGPPGE 
DGERGDDGEI GPRGLPGESG PRGLLGPKGP PGIPGPPGVR GMDGPQGPKG SLGPQGEPGP 
PGQQGTPGTQ GLPGPQGAIG PHGEKGPQGK PGLPGMPGSD GPPGHPGKEG PPGTKGNQGP 
SGPQGPLGYP GPRGVKGVDG IRGLKGHKGE KGEDGFPGFK GDIGVKGDRG EVGVPGSRGE 
DGPEGPKGRT GPTGDPGPPG LMGEKGKLGV PGLPGYPGRQ GPKGSLGFPG FPGASGEKGA 
RGLSGKSGPR GERGPTGPRG QRGPRGATGK SGAKGTSGGD GPHGPPGERG LPGPQGPNGF 
PGPKGPPGPP GKDGLPGHPG QRGEVGFQGK TGPPGPPGVV GPQGAAGETG PMGERGHPGP 
PGPPGEQGLP GTAGKEGTKG DPGPPGAPGK DGPAGLRGFP GERGLPGTAG GPGLKGNEGP 
SGPPGPAGSP GERGAAGSGG PIGPPGRPGP QGPPGAAGEK GVPGEKGPIG PTGRDGVQGP 
VGLPGPAGPP GVAGEDGDKG EVGDPGQKGT KGNKGEHGPP GPPGPIGPVG QPGAAGADGE 
PGARGPQGHF GAKGDEGTRG FNGPPGPIGL QGLPGPSGEK GETGDVGPMG PPGPPGPRGP 
AGPNGADGPQ GPPGGVGNLG PPGEKGEPGE SGSPGIQGEP GVKGPRGERG EKGESGQPGE 
PGPPGPKGPT GDDGPKGNPG PVGFPGDPGP PGEGGPRGQD GAKGDRGEDG EPGQPGSPGP 
TGENGPPGPL GKRGPAGSPG SEGRQGGKGA KGDPGAIGAP GKTGPVGPAG PAGKPGPDGL 
RGLPGSVGQQ GRPGATGQAG PPGPVGPPGL PGLRGDAGAK GEKGHPGLIG LIGPPGEQGE 
KGDRGLPGPQ GSPGQKGEMG IPGASGPIGP GGPPGLPGPA GPKGAKGATG PGGPKGEKGV 
QGPPGHPGPP GEVIQPLPIQ MPKKTRRSVD GSRLMQEDEA IPTGGAPGSP GGLEEIFGSL 
DSLREEIEQM RRPTGTQDSP ARTCQDLKLC HPELPDGEYW VDPNQGCARD AFRVFCNFTA 
GGETCVTPRD DVTQFSYVDS EGSPVGVVQL TFLRLLSVSA HQDVSYPCSG AARDGPLRLR 
GANEDELSPE TSPYVKEFRD GCQTQQGRTV LEVRTPVLEQ LPVLDASFSD LGAPPRRGGV 
LLGPVCFMG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.