Genular: Defining Cellular Identity and Function

Details for: Pcyt1a

Gene ID: 13026

Symbol: Pcyt1a

Ensembl ID: ENSMUSG00000005615

Description: phosphate cytidylyltransferase 1, choline, alpha isoform

Associated with

Glycerophospholipid biosynthesis
(R-MMU-1483206)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Phospholipid metabolism
(R-MMU-1483257)
Synthesis of pc
(R-MMU-1483191)
Biosynthetic process
(GO:0009058)
Calmodulin binding
(GO:0005516)
Catalytic activity
(GO:0003824)
Cdp-choline pathway
(GO:0006657)
Choline-phosphate cytidylyltransferase activity
(GO:0004105)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Glycogen granule
(GO:0042587)
Identical protein binding
(GO:0042802)
Lipid binding
(GO:0008289)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Molecular function inhibitor activity
(GO:0140678)
Nuclear envelope
(GO:0005635)
Nucleotidyltransferase activity
(GO:0016779)
Nucleus
(GO:0005634)
Phosphatidylcholine binding
(GO:0031210)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phospholipid biosynthetic process
(GO:0008654)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Transferase activity
(GO:0016740)

Other Information

Proteins

Choline-phosphate cytidylyltransferase A

Genular Protein ID: 3676072274

Symbol: PCY1A_MOUSE

Name: Choline-phosphate cytidylyltransferase A

UniProtKB Accession Codes:

P49586 Q542W4

Database IDs:

Citations:

PubMed ID: 8307580

Title: The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16.

PubMed ID: 8307580

DOI: 10.1016/s0888-7543(05)80377-5

PubMed ID: 7918629

Title: Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase.

PubMed ID: 7918629

DOI: 10.1016/0167-4781(94)90056-6

PubMed ID: 9148929

Title: The structure of the gene for murine CTP:phosphocholine cytidylyltransferase, Ctpct. Relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements.

PubMed ID: 9148929

DOI: 10.1074/jbc.272.20.13146

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12842190

Title: Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform.

PubMed ID: 12842190

DOI: 10.1016/s1388-1981(03)00067-2

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21343341

Title: Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.

PubMed ID: 21343341

DOI: 10.1128/mcb.00723-10

Sequence Information:

Length: 367
Mass: 41667
Checksum: 306B656D2EAAA2B3
Sequence:

MDAQSSAKVN SRKRRKEAPG PNGATEEDGI PSKVQRCAVG LRQPAPFSDE IEVDFSKPYV 
RVTMEEACRG TPCERPVRVY ADGIFDLFHS GHARALMQAK NLFPNTYLIV GVCSDELTHN 
FKGFTVMNEN ERYDAVQHCR YVDEVVRNAP WTLTPEFLAE HRIDFVAHDD IPYSSAGSDD 
VYKHIKDAGM FAPTQRTEGI STSDIITRIV RDYDVYARRN LQRGYTAKEL NVSFINEKKY 
HLQERVDKVK KKVKDVEEKS KEFVQKVEEK SIDLIQKWEE KSREFIGSFL EMFGPEGALK 
HMLKEGKGRM LQAISPKQSP SSSPTHERSP SPSFRWPFSG KTSPSSSPAS LSRCRAVTCD 
ISEDEED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pcyt1a

Associated with

Other Information

The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. PubMed ID: 8307580

Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase. PubMed ID: 7918629

The structure of the gene for murine CTP:phosphocholine cytidylyltransferase, Ctpct. Relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements. PubMed ID: 9148929

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform. PubMed ID: 12842190

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis. PubMed ID: 21343341