Genular: Defining Cellular Identity and Function

Details for: Ctsb

Gene ID: 13030

Symbol: Ctsb

Ensembl ID: ENSMUSG00000021939

Description: cathepsin B

Associated with

Adaptive immune system
(R-MMU-1280218)
Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Collagen degradation
(R-MMU-1442490)
Collagen formation
(R-MMU-1474290)
Degradation of the extracellular matrix
(R-MMU-1474228)
Extracellular matrix organization
(R-MMU-1474244)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Mhc class ii antigen presentation
(R-MMU-2132295)
Neutrophil degranulation
(R-MMU-6798695)
Toll-like receptor cascades
(R-MMU-168898)
Trafficking and processing of endosomal tlr
(R-MMU-1679131)
Apical plasma membrane
(GO:0016324)
Caveola
(GO:0005901)
Cell surface
(GO:0009986)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen binding
(GO:0005518)
Collagen catabolic process
(GO:0030574)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type peptidase activity
(GO:0008234)
Decidualization
(GO:0046697)
Endopeptidase activity
(GO:0004175)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hydrolase activity
(GO:0016787)
Kininogen binding
(GO:0030984)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Neuron apoptotic process
(GO:0051402)
Peptidase activity
(GO:0008233)
Peptidase inhibitor complex
(GO:1904090)
Peptide binding
(GO:0042277)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Protein-containing complex binding
(GO:0044877)
Protein catabolic process
(GO:0030163)
Protein self-association
(GO:0043621)
Proteoglycan binding
(GO:0043394)
Proteolysis
(GO:0006508)
Proteolysis involved in protein catabolic process
(GO:0051603)
Regulation of catalytic activity
(GO:0050790)
Sarcolemma
(GO:0042383)
Symbiont entry into host cell
(GO:0046718)
Thyroid hormone generation
(GO:0006590)

Other Information

Proteins

Cathepsin B

Genular Protein ID: 3482810980

Symbol: CATB_MOUSE

Name: Cathepsin B

UniProtKB Accession Codes:

P10605 Q3UDW7

Database IDs:

Citations:

PubMed ID: 2012677

Title: The structure of the mouse cathepsin B gene and its putative promoter.

PubMed ID: 2012677

DOI: 10.1089/dna.1991.10.159

PubMed ID: 2226854

Title: Gene structure of mouse cathepsin B.

PubMed ID: 2226854

DOI: 10.1016/0014-5793(90)81083-z

PubMed ID: 3463996

Title: Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

PubMed ID: 3463996

DOI: 10.1073/pnas.83.20.7721

PubMed ID: 1746902

Title: Characterization of multiple cathepsin B mRNAs in murine B16a melanoma.

PubMed ID: 1746902

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1889751

Title: Isolation of a cathepsin B-encoding cDNA from murine osteogenic cells.

PubMed ID: 1889751

DOI: 10.1016/0378-1119(91)90283-h

PubMed ID: 12782676

Title: Thyroid functions of mouse cathepsins B, K, and L.

PubMed ID: 12782676

DOI: 10.1172/jci15990

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 339
Mass: 37280
Checksum: 9F0A3CDF70A94040
Sequence:

MWWSLILLSC LLALTSAHDK PSFHPLSDDL INYINKQNTT WQAGRNFYNV DISYLKKLCG 
TVLGGPKLPG RVAFGEDIDL PETFDAREQW SNCPTIGQIR DQGSCGSCWA FGAVEAISDR 
TCIHTNGRVN VEVSAEDLLT CCGIQCGDGC NGGYPSGAWS FWTKKGLVSG GVYNSHVGCL 
PYTIPPCEHH VNGSRPPCTG EGDTPRCNKS CEAGYSPSYK EDKHFGYTSY SVSNSVKEIM 
AEIYKNGPVE GAFTVFSDFL TYKSGVYKHE AGDMMGGHAI RILGWGVENG VPYWLAANSW 
NLDWGDNGFF KILRGENHCG IESEIVAGIP RTDQYWGRF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ctsb

Associated with

Other Information

The structure of the mouse cathepsin B gene and its putative promoter. PubMed ID: 2012677

Gene structure of mouse cathepsin B. PubMed ID: 2226854

Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs. PubMed ID: 3463996

Characterization of multiple cathepsin B mRNAs in murine B16a melanoma. PubMed ID: 1746902

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Isolation of a cathepsin B-encoding cDNA from murine osteogenic cells. PubMed ID: 1889751

Thyroid functions of mouse cathepsins B, K, and L. PubMed ID: 12782676

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337