Genular: Defining Cellular Identity and Function

Details for: Ctsg

Gene ID: 13035

Symbol: Ctsg

Ensembl ID: ENSMUSG00000040314

Description: cathepsin G

Associated with

Activation of matrix metalloproteinases
(R-MMU-1592389)
Antimicrobial peptides
(R-MMU-6803157)
Cytokine signaling in immune system
(R-MMU-1280215)
Degradation of the extracellular matrix
(R-MMU-1474228)
Extracellular matrix organization
(R-MMU-1474244)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-1 family signaling
(R-MMU-446652)
Interleukin-1 processing
(R-MMU-448706)
Metabolism of angiotensinogen to angiotensins
(R-MMU-2022377)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Peptide hormone metabolism
(R-MMU-2980736)
Signaling by interleukins
(R-MMU-449147)
Antibacterial humoral response
(GO:0019731)
Biofilm matrix disassembly
(GO:0098786)
Caspase binding
(GO:0089720)
Cellular response to lipopolysaccharide
(GO:0071222)
Chemotaxis
(GO:0006935)
Cytoplasm
(GO:0005737)
Cytoplasmic stress granule
(GO:0010494)
Cytosol
(GO:0005829)
Defense response to bacterium
(GO:0042742)
Defense response to fungus
(GO:0050832)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heparin binding
(GO:0008201)
Hydrolase activity
(GO:0016787)
Intracellular membrane-bounded organelle
(GO:0043231)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Monocyte chemotaxis
(GO:0002548)
Negative regulation of t cell activation
(GO:0050868)
Neutrophil-mediated killing of gram-positive bacterium
(GO:0070946)
Neutrophil activation
(GO:0042119)
Nucleus
(GO:0005634)
Peptidase activity
(GO:0008233)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of immune response
(GO:0050778)
Positive regulation of platelet aggregation
(GO:1901731)
Protein binding
(GO:0005515)
Protein phosphorylation
(GO:0006468)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Receptor ligand activity
(GO:0048018)
Response to lipopolysaccharide
(GO:0032496)
Secretory granule
(GO:0030141)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

Cathepsin G

Genular Protein ID: 202630928

Symbol: CATG_MOUSE

Name: Cathepsin G

UniProtKB Accession Codes:

P28293

Database IDs:

Citations:

PubMed ID: 8453108

Title: Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene.

PubMed ID: 8453108

PubMed ID: 9211743

Title: Characterization of cDNA clones encoding mouse proteinase 3 (myeloblastine) and cathepsin G.

PubMed ID: 9211743

DOI: 10.1007/s002510050260

PubMed ID: 1577012

Title: Purification and characterization of a vimentin-specific protease in mouse myeloid leukemia cells. Regulation during differentiation and identity with cathepsin G.

PubMed ID: 1577012

DOI: 10.1111/j.1432-1033.1992.tb16861.x

Sequence Information:

Length: 261
Mass: 29096
Checksum: 5EFA1A6E10E1D7FC
Sequence:

MQPLLLLLTF ILLQGDEAGK IIGGREARPH SYPYMAFLLI QSPEGLSACG GFLVREDFVL 
TAAHCLGSSI NVTLGAHNIQ MRERTQQLIT VLRAIRHPDY NPQNIRNDIM LLQLRRRARR 
SGSVKPVALP QASKKLQPGD LCTVAGWGRV SQSRGTNVLQ EVQLRVQMDQ MCANRFQFYN 
SQTQICVGNP RERKSAFRGD SGGPLVCSNV AQGIVSYGSN NGNPPAVFTK IQSFMPWIKR 
TMRRFAPRYQ RPANSLSQAQ T

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.