Genular: Defining Cellular Identity and Function

Details for: Ctsh

Gene ID: 13036

Symbol: Ctsh

Ensembl ID: ENSMUSG00000032359

Description: cathepsin H

Associated with

Adaptive immune system
(R-MMU-1280218)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism of proteins
(R-MMU-392499)
Mhc class ii antigen presentation
(R-MMU-2132295)
Neutrophil degranulation
(R-MMU-6798695)
Surfactant metabolism
(R-MMU-5683826)
Acrosomal vesicle
(GO:0001669)
Alveolar lamellar body
(GO:0097208)
Aminopeptidase activity
(GO:0004177)
Apoptotic process
(GO:0006915)
Axoneme
(GO:0005930)
Bradykinin catabolic process
(GO:0010815)
Cysteine-type endopeptidase activator activity involved in apoptotic process
(GO:0008656)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytosol
(GO:0005829)
Dichotomous subdivision of terminal units involved in lung branching
(GO:0060448)
Endopeptidase activity
(GO:0004175)
Erk1 and erk2 cascade
(GO:0070371)
Extracellular space
(GO:0005615)
Hla-a specific activating mhc class i receptor activity
(GO:0030108)
Hydrolase activity
(GO:0016787)
Immune response
(GO:0006955)
Immune response-regulating signaling pathway
(GO:0002764)
Intracellular membrane-bounded organelle
(GO:0043231)
Kininogen binding
(GO:0030984)
Lysosome
(GO:0005764)
Membrane protein proteolysis
(GO:0033619)
Negative regulation of apoptotic process
(GO:0043066)
Neuropeptide catabolic process
(GO:0010813)
Outer dense fiber
(GO:0001520)
Peptidase activator activity involved in apoptotic process
(GO:0016505)
Peptidase activity
(GO:0008233)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of apoptotic signaling pathway
(GO:2001235)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of peptidase activity
(GO:0010952)
Protein-containing complex binding
(GO:0044877)
Protein destabilization
(GO:0031648)
Protein self-association
(GO:0043621)
Proteolysis
(GO:0006508)
Proteolysis involved in protein catabolic process
(GO:0051603)
Response to retinoic acid
(GO:0032526)
Serine-type endopeptidase activity
(GO:0004252)
Surfactant homeostasis
(GO:0043129)
T cell mediated cytotoxicity
(GO:0001913)
Thyroid hormone binding
(GO:0070324)
Zymogen activation
(GO:0031638)

Other Information

Proteins

Pro-cathepsin H

Genular Protein ID: 1551545343

Symbol: CATH_MOUSE

Name: Pro-cathepsin H

UniProtKB Accession Codes:

P49935 Q3UCD6

Database IDs:

Citations:

PubMed ID: 7722423

Title: IFN-gamma increases cathepsin H mRNA levels in mouse macrophages.

PubMed ID: 7722423

DOI: 10.1002/jlb.57.4.663

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 10395917

Title: Cathepsin expression during skeletal development.

PubMed ID: 10395917

DOI: 10.1016/s0167-4781(99)00068-8

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23830514

Title: Mutations in LRPAP1 are associated with severe myopia in humans.

PubMed ID: 23830514

DOI: 10.1016/j.ajhg.2013.06.002

Sequence Information:

Length: 333
Mass: 37170
Checksum: 96688394A87CCA36
Sequence:

MWAALPLLCA GAWLLSTGAT AELTVNAIEK FHFKSWMKQH QKTYSSVEYN HRLQMFANNW 
RKIQAHNQRN HTFKMALNQF SDMSFAEIKH KFLWSEPQNC SATKSNYLRG TGPYPSSMDW 
RKKGNVVSPV KNQGACGSCW TFSTTGALES AVAIASGKML SLAEQQLVDC AQAFNNHGCK 
GGLPSQAFEY ILYNKGIMEE DSYPYIGKDS SCRFNPQKAV AFVKNVVNIT LNDEAAMVEA 
VALYNPVSFA FEVTEDFLMY KSGVYSSKSC HKTPDKVNHA VLAVGYGEQN GLLYWIVKNS 
WGSQWGENGY FLIERGKNMC GLAACASYPI PQV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ctsh

Associated with

Other Information

IFN-gamma increases cathepsin H mRNA levels in mouse macrophages. PubMed ID: 7722423

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Cathepsin expression during skeletal development. PubMed ID: 10395917