Details for: Cux2

Gene ID: 13048

Symbol: Cux2

Ensembl ID: ENSMUSG00000042589

Description: cut-like homeobox 2

Associated with

  • Cellular response to organic substance
    (GO:0071310)
  • Cognition
    (GO:0050890)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dendrite morphogenesis
    (GO:0050775)
  • Positive regulation of dendritic spine morphogenesis
    (GO:0061003)
  • Positive regulation of excitatory postsynaptic potential
    (GO:2000463)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of synapse assembly
    (GO:0051965)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Short-term memory
    (GO:0007614)

Other Information

Genular Protein ID: 520245798

Symbol: CUX2_MOUSE

Name: Homeobox protein cut-like 2

UniProtKB Accession Codes:

P70298 Q6P1E6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 3 ExpressionAtlas 1 GO 19 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 2 iPTMnet 1

Citations:

PubMed ID: 8798433

Title: Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.

PubMed ID: 8798433

DOI: 10.1074/jbc.271.37.22624

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18033766

Title: Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone.

PubMed ID: 18033766

DOI: 10.1093/cercor/bhm199

PubMed ID: 20510857

Title: Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex.

PubMed ID: 20510857

DOI: 10.1016/j.neuron.2010.04.038

Sequence Information:

  • Length: 1426
  • Mass: 154664
  • Checksum: 485B87D1C88D2577
  • Sequence:
    • MVAPVLKSFQ AEVVALSKRS REAEAAFLSV YKQLIEAPDP VPSFEVARTL DDRLQRPSFD 
PSGQRLQDVH IAWKRCPEPP SAREQNEGTC PTGHTPANGN HLPGPEDTLV TDTLLQKNEA 
ERQKGLQEVH ITLAARLGEA EEKIKVLHSA LKATQTELLE LRRKYDEEAA SKADEVGLIM 
TNLEKANQRA EAAQREVESL REQLASVNSS IRLACCSPQG PSGEKVSFAL CSGPRLEAAL 
ASKDREILRL LKDAQQLRHS LQELEEVSAN QIADLERQLA AKSEAIEKLQ EKLEAQADYE 
EIKTELSILR AMKLASSTCS LPQTLAKPDD PLLVAKDVFF PTQKFLLEKP ALLASPEEDP 
SEDDSIKGSL GTEPPYPPQL PPPPGPEDPL SPSPAQPLLG PSLGPDGPRT FSLSPFPSLA 
PGERLAGDSL LSKHMMGPAA FKGETGNLLA FPPTFYGGAK PPSAPAASVP CPEPTGAPEA 
VDGAGPEEEQ LDTAEIAFQV KEQLLKHNIG QRVFGHYVLG LSQGSVSEIL ARPKPWRKLT 
VKGKEPFIKM KQFLSDEQNV LALRTIQVRQ RGSITPRIRT PETGSDDAIK SILEQAKKEI 
ESQKGGESKN SPASVSIPNG TASSSTSEDA IKNILEQARR EMQAQQQALL EMESGPRGRS 
VPPSPPERPS PATASQNGAL TCVKQEDGGG GSGSSSTVQA PLAVLSPAAF VQRIIRKVKS 
EIGDAGYFDH HWASDRGLLS RPYASVSPSL SSSSSYSGQP NGRAWPRGDE ATIAPEDEAA 
MGEDEAPRVG ELKAEAGAPE VGGGRLPYYP AYVPRTLKPT VPPLTPEQYE LYMYREVDTL 
ELTRQVKEKL AKNGICQRIF GEKVLGLSQG SVSDMLSRPK PWSKLTQKGR EPFIRMQLWL 
SDQLGQGQGQ APTQQPSASQ ASPTEPTSSP SPPPSPTEPE KTSQEPLGLS LESSKENQQP 
EGRASSSLGG KPFSSSQAAG GIQEMVAMSP ELDTYSITKR VKEVLTDNNL GQRLFGESIL 
GLTQGSVSDL LSRPKPWHKL SLKGREPFVR MQLWLSDPHN VEKLRDMKKL EKKAYLKRRY 
GLIGTGSDSE SPAAHSECPS PCLQPQELSL MQAKKPRVVL APAEKEALRK AYQLEPYPSQ 
QTIELLSFQL NLKTNTVINW FHNYRSRMRR EMLVEGTQDD PDFDPSGGPN VLTPGHTHRE 
PTPQSPDSET EDQKPPMKSL ELQEPEGPLQ RAAPDRALVK IKQEEGLEVD GDSQPQDVGD 
PDRGQDGPKE EHTHPLGNSD LSELAPGPFL SGTPNPDCPS LHNPQEKGTG EQVHSEPLSF 
KSTSESSCCS LEGPPNSPSV ISSPDLTTCV SPAPSSSAPI SPSLPGAPPA KVPSTSPTGD 
TAAALHPSTK VNPNLQRRHE KMANLNSIIY RLERAANREE VLEWEF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.