Details for: Cx3cr1

Gene ID: 13051

Symbol: Cx3cr1

Ensembl ID: ENSMUSG00000052336

Description: C-X3-C motif chemokine receptor 1

Associated with

Other Information

Genular Protein ID: 158788207

Symbol: CX3C1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9918795

Title: Gene cloning, RNA distribution, and functional expression of mCX3CR1, a mouse chemotactic receptor for the CX3C chemokine fractalkine.

PubMed ID: 9918795

DOI: 10.1006/bbrc.1998.9849

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10187784

Title: Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation.

PubMed ID: 10187784

DOI: 10.1074/jbc.274.15.10053

PubMed ID: 10805752

Title: Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion.

PubMed ID: 10805752

DOI: 10.1128/mcb.20.11.4106-4114.2000

PubMed ID: 11544273

Title: Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection.

PubMed ID: 11544273

DOI: 10.1172/jci12976

PubMed ID: 12871640

Title: Blood monocytes consist of two principal subsets with distinct migratory properties.

PubMed ID: 12871640

DOI: 10.1016/s1074-7613(03)00174-2

PubMed ID: 12569158

Title: Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.

PubMed ID: 12569158

DOI: 10.1172/jci15555

PubMed ID: 15653504

Title: CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance.

PubMed ID: 15653504

DOI: 10.1126/science.1102901

PubMed ID: 16675847

Title: The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

PubMed ID: 16675847

DOI: 10.1096/fj.05-5465com

PubMed ID: 16732273

Title: Control of microglial neurotoxicity by the fractalkine receptor.

PubMed ID: 16732273

DOI: 10.1038/nn1715

PubMed ID: 18322241

Title: Protective roles of the fractalkine/CX3CL1-CX3CR1 interactions in alkali-induced corneal neovascularization through enhanced antiangiogenic factor expression.

PubMed ID: 18322241

DOI: 10.4049/jimmunol.180.6.4283

PubMed ID: 18971423

Title: CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival.

PubMed ID: 18971423

DOI: 10.1182/blood-2008-07-170787

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21037587

Title: CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung.

PubMed ID: 21037587

DOI: 10.1038/nm.2253

PubMed ID: 21778362

Title: Synaptic pruning by microglia is necessary for normal brain development.

PubMed ID: 21778362

DOI: 10.1126/science.1202529

PubMed ID: 24487234

Title: Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior.

PubMed ID: 24487234

DOI: 10.1038/nn.3641

PubMed ID: 29326275

Title: CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi.

PubMed ID: 29326275

DOI: 10.1126/science.aao1503

PubMed ID: 33548172

Title: Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies.

PubMed ID: 33548172

DOI: 10.1016/j.cell.2021.01.016

Sequence Information:

  • Length: 354
  • Mass: 40266
  • Checksum: 12C745E8E3755CA9
  • Sequence:
  • MSTSFPELDL ENFEYDDSAE ACYLGDIVAF GTIFLSVFYA LVFTFGLVGN LLVVLALTNS 
    RKPKSITDIY LLNLALSDLL FVATLPFWTH YLISHEGLHN AMCKLTTAFF FIGFFGGIFF 
    ITVISIDRYL AIVLAANSMN NRTVQHGVTI SLGVWAAAIL VASPQFMFTK RKDNECLGDY 
    PEVLQEMWPV LRNSEVNILG FALPLLIMSF CYFRIIQTLF SCKNRKKARA VRLILLVVFA 
    FFLFWTPYNI MIFLETLKFY NFFPSCDMKR DLRLALSVTE TVAFSHCCLN PFIYAFAGEK 
    FRRYLGHLYR KCLAVLCGHP VHTGFSPESQ RSRQDSILSS FTHYTSEGDG SLLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.