Genular: Defining Cellular Identity and Function

Details for: Cxadr

Gene ID: 13052

Symbol: Cxadr

Ensembl ID: ENSMUSG00000022865

Description: coxsackie virus and adenovirus receptor

Associated with

Adaptive immune system
(R-MMU-1280218)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-MMU-198933)
Acrosomal vesicle
(GO:0001669)
Actin cytoskeleton organization
(GO:0030036)
Adherens junction
(GO:0005912)
Anchoring junction
(GO:0070161)
Apicolateral plasma membrane
(GO:0016327)
Av node cell-bundle of his cell adhesion involved in cell communication
(GO:0086072)
Av node cell to bundle of his cell communication
(GO:0086067)
Basolateral plasma membrane
(GO:0016323)
Beta-catenin binding
(GO:0008013)
Bicellular tight junction
(GO:0005923)
Cardiac muscle cell development
(GO:0055013)
Cardiac muscle cell proliferation
(GO:0060038)
Cell-cell adhesion
(GO:0098609)
Cell-cell junction
(GO:0005911)
Cell-cell junction organization
(GO:0045216)
Cell adhesion
(GO:0007155)
Cell adhesion molecule binding
(GO:0050839)
Cell adhesive protein binding involved in av node cell-bundle of his cell communication
(GO:0086082)
Cell body
(GO:0044297)
Cell junction
(GO:0030054)
Connexin binding
(GO:0071253)
Cytoplasm
(GO:0005737)
Defense response to virus
(GO:0051607)
Epithelial structure maintenance
(GO:0010669)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Filopodium
(GO:0030175)
Gamma-delta t cell activation
(GO:0046629)
Germ cell migration
(GO:0008354)
Growth cone
(GO:0030426)
Heart development
(GO:0007507)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
(GO:0007157)
Homotypic cell-cell adhesion
(GO:0034109)
Identical protein binding
(GO:0042802)
Integrin binding
(GO:0005178)
Intercalated disc
(GO:0014704)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Mitochondrion organization
(GO:0007005)
Negative regulation of cardiac muscle cell proliferation
(GO:0060044)
Neuromuscular junction
(GO:0031594)
Neuron projection
(GO:0043005)
Neutrophil chemotaxis
(GO:0030593)
Nucleoplasm
(GO:0005654)
Pdz domain binding
(GO:0030165)
Plasma membrane
(GO:0005886)
Positive regulation of epithelial cell proliferation involved in wound healing
(GO:0060054)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Regulation of av node cell action potential
(GO:0098904)
Signaling receptor binding
(GO:0005102)
Transepithelial transport
(GO:0070633)

Other Information

Proteins

Coxsackievirus and adenovirus receptor homolog

Genular Protein ID: 1465351048

Symbol: CXAR_MOUSE

Name: Coxsackievirus and adenovirus receptor homolog

UniProtKB Accession Codes:

P97792 O09052 Q3ULD0 Q91W66 Q99KG0 Q9DBJ8

Database IDs:

Citations:

PubMed ID: 9096397

Title: HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses.

PubMed ID: 9096397

DOI: 10.1073/pnas.94.7.3352

PubMed ID: 9036860

Title: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.

PubMed ID: 9036860

DOI: 10.1126/science.275.5304.1320

PubMed ID: 9420240

Title: The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses.

PubMed ID: 9420240

DOI: 10.1128/jvi.72.1.415-419.1998

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10814828

Title: The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain.

PubMed ID: 10814828

DOI: 10.1016/s0169-328x(00)00036-x

PubMed ID: 12763576

Title: Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system.

PubMed ID: 12763576

DOI: 10.1016/s0165-3806(03)00035-x

PubMed ID: 15533241

Title: Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs.

PubMed ID: 15533241

DOI: 10.1186/1471-2121-5-42

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20813954

Title: The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation.

PubMed ID: 20813954

DOI: 10.1126/science.1192698

PubMed ID: 20181587

Title: The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.

PubMed ID: 20181587

DOI: 10.1523/jneurosci.5725-09.2010

PubMed ID: 20813955

Title: The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.

PubMed ID: 20813955

DOI: 10.1126/science.1187996

Sequence Information:

Length: 365
Mass: 39948
Checksum: 5445B4B52A34B2A2
Sequence:

MARLLCFVLL CGIADFTSGL SITTPEQRIE KAKGETAYLP CKFTLSPEDQ GPLDIEWLIS 
PSDNQIVDQV IILYSGDKIY DNYYPDLKGR VHFTSNDVKS GDASINVTNL QLSDIGTYQC 
KVKKAPGVAN KKFLLTVLVK PSGTRCFVDG SEEIGNDFKL KCEPKEGSLP LQFEWQKLSD 
SQTMPTPWLA EMTSPVISVK NASSEYSGTY SCTVQNRVGS DQCMLRLDVV PPSNRAGTIA 
GAVIGTLLAL VLIGAILFCC HRKRREEKYE KEVHHDIRED VPPPKSRTST ARSYIGSNHS 
SLGSMSPSNM EGYSKTQYNQ VPSEDFERAP QSPTLAPAKV AAPNLSRMGA VPVMIPAQSK 
DGSIV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cxadr

Associated with

Other Information

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. PubMed ID: 9096397

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. PubMed ID: 9036860

The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses. PubMed ID: 9420240

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain. PubMed ID: 10814828

Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system. PubMed ID: 12763576

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs. PubMed ID: 15533241

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. PubMed ID: 20813954

The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells. PubMed ID: 20181587

The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. PubMed ID: 20813955