Genular: Defining Cellular Identity and Function

Details for: Cyba

Gene ID: 13057

Symbol: Cyba

Ensembl ID: ENSMUSG00000006519

Description: cytochrome b-245, alpha polypeptide

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cross-presentation of particulate exogenous antigens (phagosomes)
(R-MMU-1236973)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate nadph oxidases
(R-MMU-5668599)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Apical plasma membrane
(GO:0016324)
Cellular response to organic substance
(GO:0071310)
Cytochrome complex assembly
(GO:0017004)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Electron transfer activity
(GO:0009055)
Endosome
(GO:0005768)
Establishment of localization in cell
(GO:0051649)
Focal adhesion
(GO:0005925)
Heme binding
(GO:0020037)
Hydrogen peroxide biosynthetic process
(GO:0050665)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Mucus secretion
(GO:0070254)
Nadph oxidase complex
(GO:0043020)
Negative regulation of glomerular filtration by angiotensin
(GO:0003106)
Neuronal cell body
(GO:0043025)
Oxidoreductase activity
(GO:0016491)
Perinuclear endoplasmic reticulum
(GO:0097038)
Plasma membrane
(GO:0005886)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of defense response to bacterium
(GO:1900426)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of mucus secretion
(GO:0070257)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of reactive oxygen species biosynthetic process
(GO:1903428)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Positive regulation of superoxide anion generation
(GO:0032930)
Positive regulation of toll-like receptor 2 signaling pathway
(GO:0034137)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Reactive oxygen species metabolic process
(GO:0072593)
Regulation of release of sequestered calcium ion into cytosol
(GO:0051279)
Respiratory burst
(GO:0045730)
Sh3 domain binding
(GO:0017124)
Smooth muscle hypertrophy
(GO:0014895)
Stress fiber
(GO:0001725)
Superoxide-generating nad(p)h oxidase activity
(GO:0016175)
Superoxide anion generation
(GO:0042554)
Superoxide metabolic process
(GO:0006801)

Other Information

Proteins

Cytochrome b-245 light chain

Genular Protein ID: 498757680

Symbol: CY24A_MOUSE

Name: Cytochrome b-245 light chain

UniProtKB Accession Codes:

Q61462 Q3U820 Q9CWB9 Q9D2W2

Database IDs:

Citations:

PubMed ID: 2597164

Title: Complementary DNA for the mouse homolog of the small subunit of human cytochrome b558.

PubMed ID: 2597164

DOI: 10.1016/s0006-291x(89)80051-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19755709

Title: Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation.

PubMed ID: 19755709

DOI: 10.1126/scisignal.2000368

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21551061

Title: A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection.

PubMed ID: 21551061

DOI: 10.1126/science.1201711

PubMed ID: 26194095

Title: Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.

PubMed ID: 26194095

DOI: 10.1038/ncomms8838

PubMed ID: 28351984

Title: Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.

PubMed ID: 28351984

DOI: 10.1084/jem.20161382

Sequence Information:

Length: 192
Mass: 20748
Checksum: 10DA1F9A54F44E80
Sequence:

MGQIEWAMWA NEQALASGLI LITGGIVATA GRFTQWYFGA YSIAAGVLIC LLEYPRGKRK 
KGSTMERCGQ KYLTSVVKLF GPLTRNYYVR AALHFLLSVP AGFLLATILG TVCLAIASVI 
YLLAAIRGEQ WTPIEPKPKE RPQVGGTIKQ PPTNPPPRPP AEVRKKPSEG EEEAASAGGP 
QVNPMPVTDE VV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyba

Associated with

Other Information

Complementary DNA for the mouse homolog of the small subunit of human cytochrome b558. PubMed ID: 2597164

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. PubMed ID: 19755709

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. PubMed ID: 21551061

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst. PubMed ID: 26194095

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. PubMed ID: 28351984