Genular: Defining Cellular Identity and Function

Details for: Cycs

Gene ID: 13063

Symbol: Cycs

Ensembl ID: ENSMUSG00000063694

Description: cytochrome c, somatic

Associated with

Activation of caspases through apoptosome-mediated cleavage
(R-MMU-111459)
Apoptosis
(R-MMU-109581)
Apoptotic factor-mediated response
(R-MMU-111471)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Cytochrome c-mediated apoptotic response
(R-MMU-111461)
Cytoprotection by hmox1
(R-MMU-9707564)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Formation of apoptosome
(R-MMU-111458)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Metabolism
(R-MMU-1430728)
Mitochondrial biogenesis
(R-MMU-1592230)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Programmed cell death
(R-MMU-5357801)
Pyroptosis
(R-MMU-5620971)
Regulated necrosis
(R-MMU-5218859)
Regulation of the apoptosome activity
(R-MMU-9627069)
Release of apoptotic factors from the mitochondria
(R-MMU-111457)
Respiratory electron transport
(R-MMU-611105)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-MMU-163200)
Rna polymerase ii transcription
(R-MMU-73857)
The citric acid (tca) cycle and respiratory electron transport
(R-MMU-1428517)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional activation of mitochondrial biogenesis
(R-MMU-2151201)
Transcriptional regulation by tp53
(R-MMU-3700989)
Activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
(GO:0008635)
Apoptosome
(GO:0043293)
Apoptotic process
(GO:0006915)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Heme binding
(GO:0020037)
Hydrogen peroxide metabolic process
(GO:0042743)
Intrinsic apoptotic signaling pathway
(GO:0097193)
Mitochondrial electron transport, cytochrome c to oxygen
(GO:0006123)
Mitochondrial electron transport, ubiquinol to cytochrome c
(GO:0006122)
Mitochondrial intermembrane space
(GO:0005758)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Nucleus
(GO:0005634)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)
Regulation of protein binding
(GO:0043393)

Other Information

Proteins

Cytochrome c, somatic

Genular Protein ID: 2740697815

Symbol: CYC_MOUSE

Name: Cytochrome c, somatic

UniProtKB Accession Codes:

P62897 P00009 Q8C2S2

Database IDs:

Citations:

PubMed ID: 2987801

Title: Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes.

PubMed ID: 2987801

DOI: 10.1093/nar/13.2.617

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 191069

Title: Primary structure of mouse, rat, and guinea pig cytochrome c.

PubMed ID: 191069

DOI: 10.1021/bi00626a031

PubMed ID: 240690

Title: Change of cytochrome c structure during development of the mouse.

PubMed ID: 240690

DOI: 10.1111/j.1432-1033.1975.tb02149.x

PubMed ID: 12062423

Title: Nuclear Apaf-1 and cytochrome c redistribution following stress-induced apoptosis.

PubMed ID: 12062423

DOI: 10.1016/s0014-5793(02)02607-8

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 105
Mass: 11605
Checksum: B5BCA779BCE40492
Sequence:

MGDVEKGKKI FVQKCAQCHT VEKGGKHKTG PNLHGLFGRK TGQAAGFSYT DANKNKGITW 
GEDTLMEYLE NPKKYIPGTK MIFAGIKKKG ERADLIAYLK KATNE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cycs

Associated with

Other Information

Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes. PubMed ID: 2987801

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Primary structure of mouse, rat, and guinea pig cytochrome c. PubMed ID: 191069

Change of cytochrome c structure during development of the mouse. PubMed ID: 240690

Nuclear Apaf-1 and cytochrome c redistribution following stress-induced apoptosis. PubMed ID: 12062423

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753