Genular: Defining Cellular Identity and Function

Details for: Cyp17a1

Gene ID: 13074

Symbol: Cyp17a1

Ensembl ID: ENSMUSG00000003555

Description: cytochrome P450, family 17, subfamily a, polypeptide 1

Associated with

Androgen biosynthesis
(R-MMU-193048)
Glucocorticoid biosynthesis
(R-MMU-194002)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroid hormones
(R-MMU-196071)
Metabolism of steroids
(R-MMU-8957322)
17-alpha-hydroxyprogesterone aldolase activity
(GO:0047442)
Axon
(GO:0030424)
Cell projection
(GO:0042995)
Endoplasmic reticulum
(GO:0005783)
Glucocorticoid biosynthetic process
(GO:0006704)
Heme binding
(GO:0020037)
Hormone biosynthetic process
(GO:0042446)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Lipid metabolic process
(GO:0006629)
Lyase activity
(GO:0016829)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Monooxygenase activity
(GO:0004497)
Neuronal cell body
(GO:0043025)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Positive regulation of steroid hormone biosynthetic process
(GO:0090031)
Progesterone metabolic process
(GO:0042448)
Steroid 17-alpha-monooxygenase activity
(GO:0004508)
Steroid biosynthetic process
(GO:0006694)
Steroid metabolic process
(GO:0008202)

Other Information

Proteins

Steroid 17-alpha-hydroxylase/17,20 lyase
Q3UYU1_MOUSE

Genular Protein ID: 1094888291

Symbol: CP17A_MOUSE

Name: Steroid 17-alpha-hydroxylase/17,20 lyase

UniProtKB Accession Codes:

P27786

Database IDs:

Citations:

PubMed ID: 1840559

Title: Isolation, characterization, and chromosomal mapping of mouse P450 17 alpha-hydroxylase/C17-20 lyase.

PubMed ID: 1840559

DOI: 10.1016/0888-7543(91)90511-c

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 36640554

Title: Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).

PubMed ID: 36640554

DOI: 10.1016/j.jinorgbio.2022.112085

Sequence Information:

Length: 507
Mass: 57638
Checksum: C0916193356EFEBD
Sequence:

MWELVGLLLL ILAYFFWPKS KTPNAKFPRS LPFLPLVGSL PFLPRRGHMH ANFFKLQEKY 
GPIYSLRLGT TTAVIVGHYQ LAREVLVKKG KEFSGRPQMV TLGLLSDQGK GVAFADSSSS 
WQLHRKLVFS TFSLFRDDQK LEKMICQEAN SLCDLILTYD GESRDLSTLI FKSVINIICT 
ICFNISFENK DPILTTIQTF TEGIVDVLGH SDLVDIFPWL KIFPNKNLEM IKEHTKIREK 
TLVEMFEKCK EKFNSESLSS LTDILIQAKM NAENNNTGEG QDPSVFSDKH ILVTVGDIFG 
AGIETTSSVL NWILAFLVHN PEVKRKIQKE IDQYVGFSRT PSFNDRTHLL MLEATIREVL 
RIRPVAPLLI PHKANIDSSI GEFAIPKDTH VIINLWALHH DKNEWDQPDR FMPERFLDPT 
GSHLITPTPS YLPFGAGPRS CIGEALARQE LFIFMALLLQ RFDFDVSDDK QLPCLVGDPK 
VVFLIDPFKV KITVRQAWKD AQVEVST

Genular Protein ID: 1030095151

Symbol: Q3UYU1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UYU1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 507
Mass: 57566
Checksum: C1AD819335B81EBD
Sequence:

MWELVGLLLL ILAYFFWPKS KTPNAKFPRS LPFLPLVGSL PFLPRRGHMH ANFFKLQEKY 
GPIYSLRLGT TTAVIVGHYQ LAREVLVKKG KEFSGRPQMV TLGLLSDQGK GVAFADSSSS 
WQLHRKLVFS TFSLFRDDQK LEKMICQEAN SLCDLILTYD GESRDLSTLI FKSVINIICT 
ICFNISFENK DPILTTIQTF TEGIVDVLGH SDLVDIFPWL KIFPNKNLEM IKEHTKIREK 
TLVEMFGKCK EKFNSESLSS LTDILIQAKM NAENNNTGEG QDPSVFSDKH ILVTVGDIFG 
AGIETTSSVL NWILAFLVHN PEVKRKIQKE IDQYVGFSRT PSFNDRTHLL MLEATIREVL 
RIRPVAPLLI PHKANIDSSI GEFAIPKDTH VIINLWALHH DKNEWDQPDR FMPERFLDPT 
GSHLITPTPS YLPFGAGPRS CIGEALARQE LFIFMALLLQ RFDFDVSDDK QLPCLVGDPK 
VVFLIDPFKV KITVRQAWKD AQVEVST

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyp17a1

Associated with

Other Information

Isolation, characterization, and chromosomal mapping of mouse P450 17 alpha-hydroxylase/C17-20 lyase. PubMed ID: 1840559

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1). PubMed ID: 36640554

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073