Details for: COL17A1

Gene ID: 1308

Symbol: COL17A1

Ensembl ID: ENSG00000065618

Description: collagen type XVII alpha 1 chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 26.6357
    Cell Significance Index: 79.2200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 16.6469
    Cell Significance Index: 37.5300
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 8.0880
    Cell Significance Index: 69.5000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 7.3741
    Cell Significance Index: 100.6100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 3.8791
    Cell Significance Index: 55.2200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.6209
    Cell Significance Index: -9.7000
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 3.5766
    Cell Significance Index: 29.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.7735
    Cell Significance Index: 77.5100
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 2.3964
    Cell Significance Index: 17.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.9702
    Cell Significance Index: 871.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.9127
    Cell Significance Index: 222.9000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.6918
    Cell Significance Index: 19.2200
  • Cell Name: epithelial cell of thymus (CL0002293)
    Fold Change: 1.4748
    Cell Significance Index: 11.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4168
    Cell Significance Index: 38.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3123
    Cell Significance Index: 129.8200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.3022
    Cell Significance Index: -2.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2182
    Cell Significance Index: 1099.9800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.2150
    Cell Significance Index: 85.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9347
    Cell Significance Index: 42.3700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8982
    Cell Significance Index: 53.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8426
    Cell Significance Index: 91.6500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8153
    Cell Significance Index: 42.3500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7195
    Cell Significance Index: 117.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5386
    Cell Significance Index: 37.2500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4450
    Cell Significance Index: 9.6400
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.3637
    Cell Significance Index: 2.2600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3539
    Cell Significance Index: 63.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3340
    Cell Significance Index: 41.0700
  • Cell Name: basal-myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.3228
    Cell Significance Index: 2.3900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.2922
    Cell Significance Index: 3.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2058
    Cell Significance Index: 5.9300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0898
    Cell Significance Index: 17.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0877
    Cell Significance Index: 3.0800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0372
    Cell Significance Index: 0.9300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0340
    Cell Significance Index: 0.4900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0200
    Cell Significance Index: 10.9300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0149
    Cell Significance Index: 10.2900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0064
    Cell Significance Index: 0.3200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0019
    Cell Significance Index: 0.0400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0037
    Cell Significance Index: -7.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0058
    Cell Significance Index: -10.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0067
    Cell Significance Index: -10.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0082
    Cell Significance Index: -11.1200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0093
    Cell Significance Index: -7.0200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0118
    Cell Significance Index: -8.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0124
    Cell Significance Index: -9.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0129
    Cell Significance Index: -8.2200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0135
    Cell Significance Index: -0.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0149
    Cell Significance Index: -1.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0159
    Cell Significance Index: -8.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0172
    Cell Significance Index: -10.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0191
    Cell Significance Index: -8.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0199
    Cell Significance Index: -7.1400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0236
    Cell Significance Index: -0.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0243
    Cell Significance Index: -7.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0283
    Cell Significance Index: -5.6700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0286
    Cell Significance Index: -5.6800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0381
    Cell Significance Index: -0.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0430
    Cell Significance Index: -5.9000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0440
    Cell Significance Index: -2.0500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0507
    Cell Significance Index: -7.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0522
    Cell Significance Index: -10.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0537
    Cell Significance Index: -9.1700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0557
    Cell Significance Index: -2.4200
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0713
    Cell Significance Index: -0.4400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0716
    Cell Significance Index: -8.2100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0732
    Cell Significance Index: -0.6500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0743
    Cell Significance Index: -7.5900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0768
    Cell Significance Index: -0.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0770
    Cell Significance Index: -8.0200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0812
    Cell Significance Index: -2.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0817
    Cell Significance Index: -3.8400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0887
    Cell Significance Index: -1.8400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1007
    Cell Significance Index: -7.7300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1075
    Cell Significance Index: -0.9900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1132
    Cell Significance Index: -2.9100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1218
    Cell Significance Index: -8.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1234
    Cell Significance Index: -9.2000
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.1284
    Cell Significance Index: -1.2200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1323
    Cell Significance Index: -2.7700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1406
    Cell Significance Index: -6.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1448
    Cell Significance Index: -7.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1542
    Cell Significance Index: -9.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1568
    Cell Significance Index: -8.8000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1644
    Cell Significance Index: -4.1100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1666
    Cell Significance Index: -6.3100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1805
    Cell Significance Index: -2.7200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1817
    Cell Significance Index: -6.6700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1886
    Cell Significance Index: -9.9000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1933
    Cell Significance Index: -4.8200
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1992
    Cell Significance Index: -2.3700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1994
    Cell Significance Index: -6.9900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.2005
    Cell Significance Index: -3.0000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2185
    Cell Significance Index: -7.1600
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.2214
    Cell Significance Index: -3.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2215
    Cell Significance Index: -6.3500
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.2229
    Cell Significance Index: -3.8300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2276
    Cell Significance Index: -7.9100
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.2333
    Cell Significance Index: -3.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** COL17A1 consists of a single chain of collagen XVII, which is composed of 17 collagen triplets. 2. **Expression:** This gene is predominantly expressed in epithelial cells, including basal cells of the epidermis, stem cells, and myoepithelial cells of the mammary gland. 3. **Function:** COL17A1 is involved in the assembly and organization of the hemidesmosome, a complex structure that anchors epithelial cells to the basement membrane. 4. **Interactions:** COL17A1 interacts with other proteins, including laminin, integrins, and laminin-binding proteins, to regulate cell-cell adhesion and signaling. **Pathways and Functions:** 1. **Cell-Cell Adhesion:** COL17A1 plays a crucial role in maintaining epithelial cell adhesion to the basement membrane through its interaction with laminin and integrins. 2. **Immune Regulation:** COL17A1 modulates immune responses by regulating the interaction between epithelial cells and immune cells, such as T cells and dendritic cells. 3. **Cell Signaling:** COL17A1 is involved in the regulation of cell signaling pathways, including the TGF-β and Wnt/β-catenin pathways, which are critical for epithelial development and homeostasis. 4. **Extracellular Matrix Organization:** COL17A1 contributes to the organization and stability of the extracellular matrix, which is essential for maintaining tissue architecture and function. **Clinical Significance:** Dysregulation of COL17A1 has been implicated in various diseases, including: 1. **Autoimmune Disorders:** COL17A1 has been linked to autoimmune disorders, such as bullous pemphigoid and pemphigus, which are characterized by the loss of epithelial cell adhesion. 2. **Skin Conditions:** COL17A1 mutations have been associated with skin conditions, such as epidermolysis bullosa acquisita and dystonic epidermolysis bullosa. 3. **Cancer:** COL17A1 has been implicated in cancer progression, particularly in epithelial cancers, where it is involved in the regulation of cell adhesion and signaling. 4. **Neurological Disorders:** COL17A1 has been linked to neurological disorders, such as multiple sclerosis and amyotrophic lateral sclerosis, where it is involved in the regulation of immune responses and tissue damage. In conclusion, COL17A1 is a critical component of the hemidesmosome, which plays a vital role in maintaining epithelial integrity and regulating immune responses. Dysregulation of this gene has been implicated in various diseases, highlighting the importance of COL17A1 in maintaining tissue homeostasis and preventing disease.

Genular Protein ID: 3163795455

Symbol: COHA1_HUMAN

Name: Collagen alpha-1(XVII) chain

UniProtKB Accession Codes:

Q9UMD9 Q02802 Q5JV36 Q99018 Q9NQK9 Q9UC14

Database IDs:

AGR 1 Allergome 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 44 Ensembl 2 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 6 RefSeq 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1324962

Title: Cloning and primary structural analysis of the bullous pemphigoid autoantigen, BP180.

PubMed ID: 1324962

DOI: 10.1111/1523-1747.ep12616580

PubMed ID: 9012408

Title: Cloning of the human type XVII collagen gene (COL17A1), and detection of novel mutations in generalized atrophic benign epidermolysis bullosa.

PubMed ID: 9012408

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1748679

Title: Genomic organization of collagenous domains and chromosomal assignment of human 180-kDa bullous pemphigoid antigen-2, a novel collagen of stratified squamous epithelium.

PubMed ID: 1748679

DOI: 10.1016/s0021-9258(18)54393-3

PubMed ID: 14675210

Title: The 97-kDa (LABD97) and 120-kDa (LAD-1) fragments of bullous pemphigoid antigen 180/type XVII collagen have different N-termini.

PubMed ID: 14675210

DOI: 10.1046/j.1523-1747.2003.12607.x

PubMed ID: 9506436

Title: The 97 kDa linear IgA bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2.

PubMed ID: 9506436

DOI: 10.1046/j.1523-1747.1998.00129.x

PubMed ID: 8618013

Title: LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells.

PubMed ID: 8618013

DOI: 10.1111/1523-1747.ep12345782

PubMed ID: 8618014

Title: 97-kDa linear IgA bullous dermatosis (LAD) antigen localizes to the lamina lucida of the epidermal basement membrane.

PubMed ID: 8618014

DOI: 10.1111/1523-1747.ep12345793

PubMed ID: 9748270

Title: Two forms of collagen XVII in keratinocytes. A full-length transmembrane protein and a soluble ectodomain.

PubMed ID: 9748270

DOI: 10.1074/jbc.273.40.25937

PubMed ID: 10637308

Title: The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.

PubMed ID: 10637308

DOI: 10.1091/mbc.11.1.277

PubMed ID: 12356719

Title: Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs.

PubMed ID: 12356719

DOI: 10.1093/emboj/cdf532

PubMed ID: 12482924

Title: Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

PubMed ID: 12482924

DOI: 10.1242/jcs.00241

PubMed ID: 17545155

Title: Extracellular phosphorylation of collagen XVII by ecto-casein kinase 2 inhibits ectodomain shedding.

PubMed ID: 17545155

DOI: 10.1074/jbc.m701937200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25676728

Title: Mutations in collagen, type XVII, alpha 1 (COL17A1) cause epithelial recurrent erosion dystrophy (ERED).

PubMed ID: 25676728

DOI: 10.1002/humu.22764

PubMed ID: 8669466

Title: Compound heterozygosity for a dominant glycine substitution and a recessive internal duplication mutation in the type XVII collagen gene results in junctional epidermolysis bullosa and abnormal dentition.

PubMed ID: 8669466

PubMed ID: 9199555

Title: Three novel homozygous point mutations and a new polymorphism in the COL17A1 gene: relation to biological and clinical phenotypes of junctional epidermolysis bullosa.

PubMed ID: 9199555

DOI: 10.1086/515463

PubMed ID: 10652291

Title: Collagen XVII is destabilized by a glycine substitution mutation in the cell adhesion domain Col15.

PubMed ID: 10652291

DOI: 10.1074/jbc.275.5.3093

PubMed ID: 10951237

Title: Hemizygosity for a glycine substitution in collagen XVII: unfolding and degradation of the ectodomain.

PubMed ID: 10951237

DOI: 10.1046/j.1523-1747.2000.00049.x

PubMed ID: 11912005

Title: A novel homozygous point mutation in the COL17A1 gene in a Chinese family with generalized atrophic benign epidermolysis bullosa.

PubMed ID: 11912005

DOI: 10.1016/s0923-1811(01)00163-3

Sequence Information:

  • Length: 1497
  • Mass: 150419
  • Checksum: E01027005F3AE843
  • Sequence:
    • MDVTKKNKRD GTEVTERIVT ETVTTRLTSL PPKGGTSNGY AKTASLGGGS RLEKQSLTHG 
SSGYINSTGS TRGHASTSSY RRAHSPASTL PNSPGSTFER KTHVTRHAYE GSSSGNSSPE 
YPRKEFASSS TRGRSQTRES EIRVRLQSAS PSTRWTELDD VKRLLKGSRS ASVSPTRNSS 
NTLPIPKKGT VETKIVTASS QSVSGTYDAT ILDANLPSHV WSSTLPAGSS MGTYHNNMTT 
QSSSLLNTNA YSAGSVFGVP NNMASCSPTL HPGLSTSSSV FGMQNNLAPS LTTLSHGTTT 
TSTAYGVKKN MPQSPAAVNT GVSTSAACTT SVQSDDLLHK DCKFLILEKD NTPAKKEMEL 
LIMTKDSGKV FTASPASIAA TSFSEDTLKK EKQAAYNADS GLKAEANGDL KTVSTKGKTT 
TADIHSYGSS GGGGSGGGGG VGGAGGGPWG PAPAWCPCGS CCSWWKWLLG LLLTWLLLLG 
LLFGLIALAE EVRKLKARVD ELERIRRSIL PYGDSMDRIE KDRLQGMAPA AGADLDKIGL 
HSDSQEELWM FVRKKLMMEQ ENGNLRGSPG PKGDMGSPGP KGDRGFPGTP GIPGPLGHPG 
PQGPKGQKGS VGDPGMEGPM GQRGREGPMG PRGEAGPPGS GEKGERGAAG EPGPHGPPGV 
PGSVGPKGSS GSPGPQGPPG PVGLQGLRGE VGLPGVKGDK GPMGPPGPKG DQGEKGPRGL 
TGEPGMRGLP GAVGEPGAKG AMGPAGPDGH QGPRGEQGLT GMPGIRGPPG PSGDPGKPGL 
TGPQGPQGLP GTPGRPGIKG EPGAPGKIVT SEGSSMLTVP GPPGPPGAMG PPGPPGAPGP 
AGPAGLPGHQ EVLNLQGPPG PPGPRGPPGP SIPGPPGPRG PPGEGLPGPP GPPGSFLSNS 
ETFLSGPPGP PGPPGPKGDQ GPPGPRGHQG EQGLPGFSTS GSSSFGLNLQ GPPGPPGPQG 
PKGDKGDPGV PGALGIPSGP SEGGSSSTMY VSGPPGPPGP PGPPGSISSS GQEIQQYISE 
YMQSDSIRSY LSGVQGPPGP PGPPGPVTTI TGETFDYSEL ASHVVSYLRT SGYGVSLFSS 
SISSEDILAV LQRDDVRQYL RQYLMGPRGP PGPPGASGDG SLLSLDYAEL SSRILSYMSS 
SGISIGLPGP PGPPGLPGTS YEELLSLLRG SEFRGIVGPP GPPGPPGIPG NVWSSISVED 
LSSYLHTAGL SFIPGPPGPP GPPGPRGPPG VSGALATYAA ENSDSFRSEL ISYLTSPDVR 
SFIVGPPGPP GPQGPPGDSR LLSTDASHSR GSSSSSHSSS VRRGSSYSSS MSTGGGGAGS 
LGAGGAFGEA AGDRGPYGTD IGPGGGYGAA AEGGMYAGNG GLLGADFAGD LDYNELAVRV 
SESMQRQGLL QGMAYTVQGP PGQPGPQGPP GISKVFSAYS NVTADLMDFF QTYGAIQGPP 
GQKGEMGTPG PKGDRGPAGP PGHPGPPGPR GHKGEKGDKG DQVYAGRRRR RSIAVKP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.