Genular: Defining Cellular Identity and Function

Details for: Cyp24a1

Gene ID: 13081

Symbol: Cyp24a1

Ensembl ID: ENSMUSG00000038567

Description: cytochrome P450, family 24, subfamily a, polypeptide 1

Associated with

Biological oxidations
(R-MMU-211859)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroids
(R-MMU-8957322)
Phase i - functionalization of compounds
(R-MMU-211945)
Vitamin d (calciferol) metabolism
(R-MMU-196791)
Vitamins
(R-MMU-211916)
1-alpha,25-dihydroxyvitamin d3 23-hydroxylase activity
(GO:0062181)
1-alpha,25-dihydroxyvitamin d3 24-hydroxylase activity
(GO:0030342)
25-hydroxycholecalciferol-23-hydroxylase activity
(GO:0062180)
25-hydroxycholecalciferol-24-hydroxylase activity
(GO:0008403)
Heme binding
(GO:0020037)
Iron ion binding
(GO:0005506)
Lipid metabolic process
(GO:0006629)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Response to vitamin d
(GO:0033280)
Vitamin d 24-hydroxylase activity
(GO:0070576)
Vitamin d 25-hydroxylase activity
(GO:0070643)
Vitamin d catabolic process
(GO:0042369)
Vitamin d metabolic process
(GO:0042359)

Other Information

Proteins

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Genular Protein ID: 2104708161

Symbol: CP24A_MOUSE

Name: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

UniProtKB Accession Codes:

Q64441

Database IDs:

Citations:

PubMed ID: 7578252

Title: Molecular cloning of 25-hydroxyvitamin D-3 24-hydroxylase (Cyp-24) from mouse kidney: its inducibility by vitamin D-3.

PubMed ID: 7578252

DOI: 10.1016/0167-4781(95)00147-9

PubMed ID: 9165006

Title: Mouse vitamin D-24-hydroxylase: molecular cloning, tissue distribution, and transcriptional regulation by 1alpha,25-dihydroxyvitamin D3.

PubMed ID: 9165006

DOI: 10.1210/endo.138.6.5170

PubMed ID: 14528024

Title: Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system.

PubMed ID: 14528024

DOI: 10.1210/me.2003-0048

Sequence Information:

Length: 514
Mass: 59453
Checksum: 3D38BA9235177A42
Sequence:

MSCPIDKRRP LIAFLRRLRD LGQPPRSVTS KAHVKRAPKE VPLCPLMTDG ETRNVTSLPG 
PTNWPLLGSL LEIFWKGGLK KQHDTLAEYH KKYGQIFRMK LGSFDSVHLG SPSLLEALYR 
TESAHPQRLE IKPWKAYRDH RNEAYGLMIL EGQEWQRVRS AFQKKLMKPV EIMKLDKKIN 
EVLADFMGQI DELRDERGRI QDLYSELNKW SFESICLVLY EKRFGLLQKD TEEEALTFIA 
AIKTMMSTFG KMMVTPVELH KRLNTKVWQA HTLAWDTIFK SVKPCIDHRL ERYSQQPGAD 
FLCDIYQQDH LSKKELYAAV TELQLAAVET TANSLMWILY NLSRNPQVQQ RLLREIQSVL 
PDNQTPRAED VRNMPYLKAC LKESMRLTPS VPFTTRTLDK PTVLGEYTLP KGTVLTLNTQ 
VLGSSEDNFE DADKFRPERW LEKEKKINPF AHLPFGVGKR MCIGRRLAEL QLHLALCWII 
QKYNIVATDS EPVEMLHLGI LVPSRELPIA FCPR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.