Genular: Defining Cellular Identity and Function

Details for: Cyp26a1

Gene ID: 13082

Symbol: Cyp26a1

Ensembl ID: ENSMUSG00000024987

Description: cytochrome P450, family 26, subfamily a, polypeptide 1

Associated with

Biological oxidations
(R-MMU-211859)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Metabolism
(R-MMU-1430728)
Phase i - functionalization of compounds
(R-MMU-211945)
Ra biosynthesis pathway
(R-MMU-5365859)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by retinoic acid
(R-MMU-5362517)
Signal transduction
(R-MMU-162582)
Vitamins
(R-MMU-211916)
All-trans retinoic acid 18-hydroxylase activity
(GO:0062183)
Anterior/posterior pattern specification
(GO:0009952)
Cellular response to retinoic acid
(GO:0071300)
Central nervous system development
(GO:0007417)
Endoplasmic reticulum
(GO:0005783)
Heme binding
(GO:0020037)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monooxygenase activity
(GO:0004497)
Neural crest cell development
(GO:0014032)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, nad(p)h as one donor, and incorporation of one atom of oxygen
(GO:0016709)
Retinoic acid 4-hydroxylase activity
(GO:0008401)
Retinoic acid binding
(GO:0001972)
Retinoic acid catabolic process
(GO:0034653)
Retinoic acid metabolic process
(GO:0042573)
Retinoic acid receptor signaling pathway
(GO:0048384)
Sterol metabolic process
(GO:0016125)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

Cytochrome P450 26A1
A0A0R4J061_MOUSE

Genular Protein ID: 4094183846

Symbol: CP26A_MOUSE

Name: Cytochrome P450 26A1

UniProtKB Accession Codes:

O55127 Q9R1F4

Database IDs:

Citations:

PubMed ID: 9250660

Title: Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos.

PubMed ID: 9250660

DOI: 10.1093/emboj/16.14.4163

PubMed ID: 9442090

Title: Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha.

PubMed ID: 9442090

DOI: 10.1074/jbc.273.4.2409

PubMed ID: 11063033

Title: Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system.

PubMed ID: 11063033

DOI: 10.3109/03008209809017046

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15911617

Title: Metabolism and transactivation activity of 13,14-dihydroretinoic acid.

PubMed ID: 15911617

DOI: 10.1074/jbc.m503520200

Sequence Information:

Length: 497
Mass: 56178
Checksum: 33B07D7C29134471
Sequence:

MGLPALLASA LCTFVLPLLL FLAALKLWDL YCVSSRDRSC ALPLPPGTMG FPFFGETLQM 
VLQRRKFLQM KRRKYGFIYK THLFGRPTVR VMGADNVRRI LLGEHRLVSV HWPASVRTIL 
GAGCLSNLHD SSHKQRKKVI MQAFSREALQ CYVLVIAEEV SSCLEQWLSC GERGLLVYPE 
VKRLMFRIAM RILLGCEPGP AGGGEDEQQL VEAFEEMTRN LFSLPIDVPF SGLYRGVKAR 
NLIHARIEEN IRAKIRRLQA TEPDGGCKDA LQLLIEHSWE RGERLDMQAL KQSSTELLFG 
GHETTASAAT SLITYLGLYP HVLQKVREEI KSKGLLCKSN QDNKLDMETL EQLKYIGCVI 
KETLRLNPPV PGGFRVALKT FELNGYQIPK GWNVIYSICD THDVADIFTN KEEFNPDRFI 
VPHPEDASRF SFIPFGGGLR SCVGKEFAKI LLKIFTVELA RHCDWQLLNG PPTMKTSPTV 
YPVDNLPARF TYFQGDI

Genular Protein ID: 3485655008

Symbol: A0A0R4J061_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J061

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 497
Mass: 56123
Checksum: 03BE8BD4D0672F96
Sequence:

MGLPALLASA LCTFVLPLLL FLAALKLWDL YCVSSRDRSC ALPLPPGTMG FPFFGETLQM 
VLQRRKFLQM KRRKYGFIYK THLFGRPTVR VMGADNVRRI LLGEHRLVSV HWPASVRTIL 
GAGCLSNLHD SSHKQRKKVI MQAFSREALQ CYVPVIAEEV SSCLEQWLSC GERGLLVYPE 
VKRLMFRIAM RILLGCEPGP AGGGEDEQQL VEAFEEMTRN LFSLPIDVPF SGLYRGVKAR 
NLIHARIEEN IRAKIRRLQA TEPDGGCKDA LQLLIEHSWE RGERLDMQAL KQSSTELLFG 
GHETTASAAT SLITYLGLYP HVLQKVREEI KSKGLLCKSN QDNKLDMETL EQLKYTGCVI 
KETLRLNPPV PGGFRVALKT FELNGYQIPK GWNVIYSICD THDVADIFTN KEEFNPDRFI 
VPHPEDASRF SFIPFGGGLR SCVGKEFAKI LLKIFTVELA RHCDWQLLNG PPTMKTSPTV 
YPVDNLPARF THFQGDI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyp26a1

Associated with

Other Information

Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. PubMed ID: 9250660

Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha. PubMed ID: 9442090

Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system. PubMed ID: 11063033

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Metabolism and transactivation activity of 13,14-dihydroretinoic acid. PubMed ID: 15911617