Genular: Defining Cellular Identity and Function

Details for: Cyp2a12

Gene ID: 13085

Symbol: Cyp2a12

Ensembl ID: ENSMUSG00000060407

Description: cytochrome P450, family 2, subfamily a, polypeptide 12

Associated with

Biological oxidations
(R-MMU-211859)
Cyp2e1 reactions
(R-MMU-211999)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Fatty acids
(R-MMU-211935)
Metabolism
(R-MMU-1430728)
Phase i - functionalization of compounds
(R-MMU-211945)
Xenobiotics
(R-MMU-211981)
Arachidonic acid epoxygenase activity
(GO:0008392)
Aromatase activity
(GO:0070330)
Coumarin metabolic process
(GO:0009804)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Epoxygenase p450 pathway
(GO:0019373)
Heme binding
(GO:0020037)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
(GO:0016712)
Steroid hydroxylase activity
(GO:0008395)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

Cytochrome P450 2A12

Genular Protein ID: 2095623841

Symbol: CP2AC_MOUSE

Name: Cytochrome P450 2A12

UniProtKB Accession Codes:

P56593 Q8VCW9

Database IDs:

Citations:

PubMed ID: 8484736

Title: Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

PubMed ID: 8484736

DOI: 10.1042/bj2910569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 492
Mass: 56179
Checksum: 38FD449996825F44
Sequence:

MLGSGLLLLA ILAFLSVMVL VSVWQQKIRG KLPPGPIPLP FIGNYLQLNR KDVYSSITQL 
QEHYGPVFTI HLGPRRVVVL YGYDAVKEAL VDHAEEFSGR GEQATFNTLF KGYGVAFSNG 
ERAKQLRRFS IATLRDFGMG KRGVEERIQE EAGCLIKMLQ GTCGAPIDPT IYLSKTASNV 
ISSIVFGDRF NYEDKEFLSL LQMMGQVNKF AASPTGQLYD MFHSVMKYLP GPQQQIIKDS 
HKLEDFMIQK VKQNQSTLDP NSPRDFIDSF LIHMQKEKYV NSEFHMKNLV MTSLNLFFAG 
SETVSSTLRY GFLLLMKHPD VEAKVHEEID RVIGRNRQPQ YEDHMKMPYT QAVINEIQRF 
SNFAPLGIPR RITKDTSFRG FFLPKGTEVF PILGSLMTDP KFFSSPKDFN PQHFLDDKGQ 
LKKIPAFLPF STGKRFCLGD SLAKMELFLF FTTILQNFRF KFPRKLEDIN ESPTPEGFTR 
IIPKYTMSFV PI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.