Genular: Defining Cellular Identity and Function

Details for: Cyp2e1

Gene ID: 13106

Symbol: Cyp2e1

Ensembl ID: ENSMUSG00000025479

Description: cytochrome P450, family 2, subfamily e, polypeptide 1

Associated with

Aspirin adme
(R-MMU-9749641)
Biological oxidations
(R-MMU-211859)
Biosynthesis of dha-derived spms
(R-MMU-9018677)
Biosynthesis of maresin-like spms
(R-MMU-9027307)
Biosynthesis of maresins
(R-MMU-9018682)
Biosynthesis of specialized proresolving mediators (spms)
(R-MMU-9018678)
Cyp2e1 reactions
(R-MMU-211999)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Drug adme
(R-MMU-9748784)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Paracetamol adme
(R-MMU-9753281)
Phase i - functionalization of compounds
(R-MMU-211945)
Xenobiotics
(R-MMU-211981)
4-nitrophenol 2-monooxygenase activity
(GO:0018601)
4-nitrophenol metabolic process
(GO:0018960)
Arachidonic acid epoxygenase activity
(GO:0008392)
Aromatase activity
(GO:0070330)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Enzyme binding
(GO:0019899)
Epoxygenase p450 pathway
(GO:0019373)
Fatty acid metabolic process
(GO:0006631)
Golgi membrane
(GO:0000139)
Heme binding
(GO:0020037)
Heterocycle metabolic process
(GO:0046483)
Hsp70 protein binding
(GO:0030544)
Hsp90 protein binding
(GO:0051879)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Lipid hydroxylation
(GO:0002933)
Lipid metabolic process
(GO:0006629)
Long-chain fatty acid metabolic process
(GO:0001676)
Long-chain fatty acid omega-1 hydroxylase activity
(GO:0120319)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrion
(GO:0005739)
Monooxygenase activity
(GO:0004497)
Monoterpenoid metabolic process
(GO:0016098)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
(GO:0016712)
Response to bacterium
(GO:0009617)
Steroid metabolic process
(GO:0008202)
Triglyceride metabolic process
(GO:0006641)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

Cytochrome P450 2E1

Genular Protein ID: 522492139

Symbol: CP2E1_MOUSE

Name: Cytochrome P450 2E1

UniProtKB Accession Codes:

Q05421 Q9Z198

Database IDs:

Citations:

PubMed ID: 8344939

Title: Mouse ethanol-inducible cytochrome P-450 (P450IIE1). Characterization of cDNA clones and testosterone induction in kidney tissue.

PubMed ID: 8344939

DOI: 10.1016/s0021-9258(19)85459-5

PubMed ID: 1536649

Title: cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1.

PubMed ID: 1536649

DOI: 10.1042/bj2810689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6851839

Title: Primary structure of the repeating element B2 and of the adjoining sequences in cloned mRNA actively transcribing in mouse liver cells.

PubMed ID: 6851839

PubMed ID: 6194512

Title: Mouse ubiquitous B2 repeat in polysomal and cytoplasmic poly(A)+RNAs: unidirectional orientation and 3'-end localization.

PubMed ID: 6194512

DOI: 10.1093/nar/11.18.6541

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 493
Mass: 56805
Checksum: 4031AB016DA56A9C
Sequence:

MAVLGITVAL LVWIATLLLV SIWKQIYRSW NLPPGPFPIP FFGNIFQLDL KDIPKSLTKL 
AKRFGPVFTL HLGQRRIVVL HGYKAVKEVL LNHKNEFSGR GDIPVFQEYK NKGIIFNNGP 
TWKDVRRFSL SILRDWGMGK QGNEARIQRE AHFLVEELKK TKGQPFDPTF LIGCAPCNVI 
ADILFNKRFD YDDKKCLELM SLFNENFYLL STPWIQAYNY FSDYLQYLPG SHRKVMKNVS 
EIRQYTLGKA KEHLKSLDIN CPRDVTDCLL IEMEKEKHSQ EPMYTMENIS VTLADLFFAG 
TETTSTTLRY GLLILMKYPE IEEKLHEEID RVIGPSRAPA VRDRMNMPYM DAVVHEIQRF 
INLVPSNLPH EATRDTVFRG YVIPKGTVVI PTLDSLLFDN YEFPDPETFK PEHFLNENGK 
FKYSDYFKAF SAGKRVCVGE GLARMELFLL LSAILQHFNL KSLVDPKDID LSPVTIGFGS 
IPREFKLCVI PRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyp2e1

Associated with

Other Information

Mouse ethanol-inducible cytochrome P-450 (P450IIE1). Characterization of cDNA clones and testosterone induction in kidney tissue. PubMed ID: 8344939

cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1. PubMed ID: 1536649

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Primary structure of the repeating element B2 and of the adjoining sequences in cloned mRNA actively transcribing in mouse liver cells. PubMed ID: 6851839

Mouse ubiquitous B2 repeat in polysomal and cytoplasmic poly(A)+RNAs: unidirectional orientation and 3'-end localization. PubMed ID: 6194512