Genular: Defining Cellular Identity and Function

Details for: Cyp4a10

Gene ID: 13117

Symbol: Cyp4a10

Ensembl ID: ENSMUSG00000066072

Description: cytochrome P450, family 4, subfamily a, polypeptide 10

Associated with

Arachidonic acid metabolism
(R-MMU-2142753)
Biological oxidations
(R-MMU-211859)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Eicosanoids
(R-MMU-211979)
Fatty acid metabolism
(R-MMU-8978868)
Fatty acids
(R-MMU-211935)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Miscellaneous substrates
(R-MMU-211958)
Phase i - functionalization of compounds
(R-MMU-211945)
Synthesis of leukotrienes (lt) and eoxins (ex)
(R-MMU-2142691)
Alkane 1-monooxygenase activity
(GO:0018685)
Apical plasma membrane
(GO:0016324)
Arachidonic acid epoxygenase activity
(GO:0008392)
Arachidonic acid metabolic process
(GO:0019369)
Arachidonic acid monooxygenase activity
(GO:0008391)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Fatty acid metabolic process
(GO:0006631)
Heme binding
(GO:0020037)
Icosanoid biosynthetic process
(GO:0046456)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Kidney development
(GO:0001822)
Lauric acid metabolic process
(GO:0048252)
Leukotriene-b4 20-monooxygenase activity
(GO:0050051)
Linoleic acid metabolic process
(GO:0043651)
Lipid metabolic process
(GO:0006629)
Long-chain fatty acid omega-hydroxylase activity
(GO:0102033)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)

Other Information

Proteins

Cytochrome P450 4A10

Genular Protein ID: 4123192408

Symbol: CP4AA_MOUSE

Name: Cytochrome P450 4A10

UniProtKB Accession Codes:

O88833 A2A976 Q9DCS5

Database IDs:

Citations:

PubMed ID: 8031839

Title: Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

PubMed ID: 8031839

DOI: 10.1016/0304-4165(94)90134-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16691295

Title: Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

PubMed ID: 16691295

DOI: 10.1172/jci27546

PubMed ID: 17112342

Title: Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

PubMed ID: 17112342

DOI: 10.1042/bj20061328

Sequence Information:

Length: 509
Mass: 58330
Checksum: 94F22CE77BD3EDC0
Sequence:

MSVSALSPTR FADSLSGFLQ VASVLGLLLL LVKAVQFYLH RQWLLKAFQQ FPSPPFHWFF 
GHEKFKGDQE LQEIVSCIEN FPSAFPRWFW GSKAYLTVYD PDYMKVILGR SDPKANGAYR 
LLAPWIGYGL LLLNGQPWFQ HRRMLTPAFH YDILKPYVKN MADSIRLMLD KWERLADQDS 
SIEIFQHISL MTLDTVMKCA FSHKGSVQVD GNYRTYLQAI GDLNNLFHSR VRNIFHQNDT 
IYKLSSNGRL AKQACQLAHD HTDGVIKLRK DQLQDEGELE KIKKKRRLDF LDILLFARME 
NGDSMSDKDL RAEVDTFMFE GHDTTASGVS WIFYALATHP DHQQRCREEV QSLLGDGSSI 
TWDHLDQIPY TTMCIKEALR LYPPVPGIVR ELSTSVTFPD GRSLPKGVQV TLSIYGLHHN 
PKVWPNPEVF DPSRFAPDSP RHSHSFLPFS GGARNCIGKQ FAMSELKVIV ALTLLRFELL 
PDPTRVPMPL ARLVLKSKNG IYLHLKKLH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyp4a10

Associated with

Other Information

Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney. PubMed ID: 8031839

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. PubMed ID: 16691295