Genular: Defining Cellular Identity and Function

Details for: Cyp4a14

Gene ID: 13119

Symbol: Cyp4a14

Ensembl ID: ENSMUSG00000028715

Description: cytochrome P450, family 4, subfamily a, polypeptide 14

Associated with

Arachidonic acid metabolism
(R-MMU-2142753)
Biological oxidations
(R-MMU-211859)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Eicosanoids
(R-MMU-211979)
Fatty acid metabolism
(R-MMU-8978868)
Fatty acids
(R-MMU-211935)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Miscellaneous substrates
(R-MMU-211958)
Phase i - functionalization of compounds
(R-MMU-211945)
Synthesis of leukotrienes (lt) and eoxins (ex)
(R-MMU-2142691)
16-hydroxypalmitate dehydrogenase activity
(GO:0103002)
Alkane 1-monooxygenase activity
(GO:0018685)
Apical plasma membrane
(GO:0016324)
Arachidonic acid binding
(GO:0050544)
Arachidonic acid epoxygenase activity
(GO:0008392)
Arachidonic acid metabolic process
(GO:0019369)
Arachidonic acid monooxygenase activity
(GO:0008391)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Extracellular space
(GO:0005615)
Fatty acid binding
(GO:0005504)
Heme binding
(GO:0020037)
Icosanoid biosynthetic process
(GO:0046456)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Kidney development
(GO:0001822)
Lauric acid metabolic process
(GO:0048252)
Leukotriene-b4 20-monooxygenase activity
(GO:0050051)
Linoleic acid metabolic process
(GO:0043651)
Long-chain fatty acid omega-hydroxylase activity
(GO:0102033)
Medium-chain fatty acid omega-hydroxylase activity
(GO:0140981)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)

Other Information

Proteins

CYPIVA14

Genular Protein ID: 977301110

Symbol: CP4AE_MOUSE

Name: CYPIVA14

UniProtKB Accession Codes:

O35728 A2A975 Q3UER2 Q5EBH0

Database IDs:

Citations:

PubMed ID: 9271096

Title: A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.

PubMed ID: 9271096

DOI: 10.1042/bj3250741

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17112342

Title: Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

PubMed ID: 17112342

DOI: 10.1042/bj20061328

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 507
Mass: 58720
Checksum: EB46205838D4549C
Sequence:

MGFFLFSPTR YLDGISGFFQ WAFLLSLFLV LFKAVQFYLR RQWLLKTLQH FPCMPSHWLW 
GHHLKDKELQ QILIWVEKFP SACLQCLSGS NIRVLLYDPD YVKVVLGRSD PKASGIYQFF 
APWIGYGLLL LNGKKWFQHR RMLTPAFHYD ILKPYVKIMA DSVNIMLDKW EKLDGQDHPL 
EIFHCVSLMT LDTVMKCAFS YQGSVQLDEN SKLYTKAVED LNNLTFFRLR NAFYKYNIIY 
NMSSDGRLSH HACQIAHEHT DGVIKMRKSQ LQNEEELQKA RKKRHLDFLD ILLFARMEDR 
NSLSDEDLRA EVDTFMFEGH DTTASGISWI FYALATHPEH QQRCREEVQS ILGDGTSVTW 
DHLGQMPYTT MCIKEALRLY PPVISVSREL SSPVTFPDGR SIPKGITATI SIYGLHHNPR 
FWPNPKVFDP SRFAPDSSHH SHAYLPFSGG SRNCIGKQFA MNELKVAVAL TLLRFELLPD 
PTRIPVPIAR LVLKSKNGIH LCLKKLR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cyp4a14

Associated with

Other Information

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans. PubMed ID: 9271096

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation. PubMed ID: 17112342