Details for: Dach1

Gene ID: 13134

Symbol: Dach1

Ensembl ID: ENSMUSG00000055639

Description: dachshund family transcription factor 1

Associated with

  • Cytoplasm
    (GO:0005737)
  • Cytosol
    (GO:0005829)
  • Development of primary female sexual characteristics
    (GO:0046545)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Epithelial cell proliferation
    (GO:0050673)
  • Golgi apparatus
    (GO:0005794)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of cell proliferation involved in contact inhibition
    (GO:0060244)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of dna biosynthetic process
    (GO:2000279)
  • Negative regulation of fibroblast proliferation
    (GO:0048147)
  • Negative regulation of transcription by competitive promoter binding
    (GO:0010944)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nuclear speck
    (GO:0016607)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of nuclear cell cycle dna replication
    (GO:0033262)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Respiratory gaseous exchange by respiratory system
    (GO:0007585)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Suckling behavior
    (GO:0001967)
  • Transcription regulator complex
    (GO:0005667)
  • Type b pancreatic cell proliferation
    (GO:0044342)

Other Information

Genular Protein ID: 1878391297

Symbol: DACH1_MOUSE

Name: Dachshund homolog 1

UniProtKB Accession Codes:

Q9QYB2 B2RUG1 O88716 Q8BPQ0 Q8C8D7 Q9QY47 Q9R218 Q9Z0Y5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 Ensembl 2 GO 27 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10502110

Title: Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene.

PubMed ID: 10502110

DOI: 10.1007/s004270050286

PubMed ID: 9915577

Title: Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud.

PubMed ID: 9915577

DOI: 10.1002/(sici)1097-0177(199901)214:1<66::aid-dvdy7>3.0.co;2-7

PubMed ID: 10502109

Title: Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs.

PubMed ID: 10502109

DOI: 10.1007/s004270050285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 9651501

Title: Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb.

PubMed ID: 9651501

DOI: 10.1016/s0925-4773(98)00071-9

PubMed ID: 12215533

Title: Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein.

PubMed ID: 12215533

DOI: 10.1128/mcb.22.19.6759-6766.2002

PubMed ID: 12130660

Title: Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

PubMed ID: 12130660

DOI: 10.1126/science.1073263

PubMed ID: 14628042

Title: Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

PubMed ID: 14628042

DOI: 10.1038/nature02083

PubMed ID: 11543628

Title: Dach: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homolog.

PubMed ID: 11543628

DOI: 10.1006/geno.2001.6618

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 751
  • Mass: 77972
  • Checksum: 0679337DBA742EC9
  • Sequence:
    • MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS GPTLFRPEPI 
ASSASSSAAA TVTSPGGGGG GSGGGGGSGG NGGGGGSNCN PSLAAGSSGG GVSAGGGGAS 
STPITASTGS SSSSSSSSSS SSSSSSSSSS SSSSSSCGPL PGKPVYSTPS PVENTPQNNE 
CKMVDLRGAK VASFTVEGCE LICLPQAFDL FLKHLVGGLH TVYTKLKRLE ITPVVCNVEQ 
VRILRGLGAI QPGVNRCKLI SRKDFETLYN DCTNASSRPG RPPKRTQSVT SPENSHIMPH 
SVPGLMSPGI IPPTGLTAAA AAAAAATNAA IAEAMKVKKI KLEAMSNYHA SNNQHGADSE 
NGDMNSSVGS SGGSWDKETL HSPPSQGSQA PVAHARMPAA FSLPVSHPLN HLQHSHLPPN 
GLELPFMMMP HPLIPVSLPP ASVTMAMSQM NHLSTIANMA AAAQVQSPPS RVETSVIKER 
VPDSPSPAPS LEEGRRPGSH PSSHRSSSVS SSPARTESSS DRIPVHQNGL SMNQMLMGLS 
PNVLPGPKEG DLAGHDMGHE SKRIHIEKDE TPLSTPTARD SIDKLSLTGH GQPLPPGFPS 
PFLFPDGLSS IETLLTNIQG LLKVAIDNAR AQEKQVQLEK TELKMDFLRE RELRETLEKQ 
LAMEQKNRAI VQKRLKKEKK AKRKLQEALE FETKRREQAE QTLKQAASAD SLRVLNDSLT 
PEIEADRSGG RADAERTIQD GRLYLKTTVM Y

Genular Protein ID: 1017349966

Symbol: Q80WU5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q80WU5

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 RefSeq 2 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 155
  • Mass: 13663
  • Checksum: CD1B054DBC769450
  • Sequence:
    • MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS GPTLFRPEPI 
ASSASSSAAA TVTSPGGGGG GSGGGGGSGG NGGGGGSNCN PSLAAGSSGG GVSAGGGGAS 
STPITASTGS SSSSSSSSSS SSSCSCCSCY QCSYC

Genular Protein ID: 3188758775

Symbol: Q3UTV2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UTV2

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Gene3D 1 InterPro 3 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 673
  • Mass: 69554
  • Checksum: 9B74AF59CC22D226
  • Sequence:
    • MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS GPTLFRPEPI 
ASSASSSAAA TVTSPGGGGG GSGGGGGSGG NGGGGGSNCN PSLAAGSSGG GVSAGGGGAS 
STPITASTGS SSSSSSSSSS SSSSSSSSSS SSSSSSCGPL PGKPVYSTPS PVENTPQNNE 
CKMVDLRGAK VASFTVEGCE LICLPQAFDL FLKHLVGGLH TVYTKLKRLE ITPVVCNVEQ 
VRILRGLGAI QPGVNRCKLI SRKDFETLYN DCTNASSRPG RPPKRTQSVT SPENSHIMSH 
SVPGLMSPGI IPPTGLTAAA AAAAAATNAA IAEAMKVKKI KLEAMSNYHA SNNQHGADSE 
NGDMNSSVGL ELPFMMMPHP LIPVSLPPAS VTMAMSQMNH LSTIANMAAA AQVQSPPSRV 
ETSVIKERVP DSPSPAPSLE EGRRPGSHPS SHRSSSVSSS PARTESSSDR IPVHQNGLSM 
NQMLMGLSPN VLPGPKEGDL AGHDMGHESK RIHIEKDETP LSTPTARDSI DKLSLTGHGQ 
PLPPGFPSPF LFPDGLSSIE TLLTNIQGLL KVAIDNARAQ EKQVQLEKTE LKMDFLRERE 
LRETLEKQLA MEQKNRAIVQ KRLKKEKKAK RKLQEALEFE TKRREQAEQT LKQAASADSL 
RVLNDSLTPE IEG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.