Details for: COPB1

Gene ID: 1315

Symbol: COPB1

Ensembl ID: ENSG00000129083

Description: COPI coat complex subunit beta 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 368.1244
    Cell Significance Index: -57.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 221.0190
    Cell Significance Index: -56.0600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 145.6253
    Cell Significance Index: -59.9900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 134.3083
    Cell Significance Index: -63.4100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 125.6593
    Cell Significance Index: -51.0500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 115.3124
    Cell Significance Index: -59.3200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 53.8051
    Cell Significance Index: -51.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 49.6611
    Cell Significance Index: -61.2300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.2161
    Cell Significance Index: -56.8400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 15.7778
    Cell Significance Index: -62.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.4236
    Cell Significance Index: -41.2300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.4098
    Cell Significance Index: -27.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.3187
    Cell Significance Index: 31.6400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6643
    Cell Significance Index: 44.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5861
    Cell Significance Index: 285.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.5856
    Cell Significance Index: 194.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1989
    Cell Significance Index: 240.4900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1861
    Cell Significance Index: 32.2900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.1515
    Cell Significance Index: 53.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1482
    Cell Significance Index: 627.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1177
    Cell Significance Index: 221.8200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0603
    Cell Significance Index: 145.6100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6957
    Cell Significance Index: 307.5700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6378
    Cell Significance Index: 228.7800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6352
    Cell Significance Index: 29.8600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.6268
    Cell Significance Index: 13.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6186
    Cell Significance Index: 79.3000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5750
    Cell Significance Index: 29.9500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5431
    Cell Significance Index: 375.6400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5283
    Cell Significance Index: 29.6500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5092
    Cell Significance Index: 14.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4426
    Cell Significance Index: 22.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3933
    Cell Significance Index: 8.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3181
    Cell Significance Index: 20.5300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3142
    Cell Significance Index: 22.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3044
    Cell Significance Index: 51.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2725
    Cell Significance Index: 32.1400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2676
    Cell Significance Index: 12.1300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2226
    Cell Significance Index: 2.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2217
    Cell Significance Index: 21.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1927
    Cell Significance Index: 174.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1784
    Cell Significance Index: 33.9500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1690
    Cell Significance Index: 12.9700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1185
    Cell Significance Index: 15.3200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1091
    Cell Significance Index: 8.1300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0672
    Cell Significance Index: 126.5400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0517
    Cell Significance Index: 8.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0376
    Cell Significance Index: 23.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0143
    Cell Significance Index: 0.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0041
    Cell Significance Index: 3.0100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0033
    Cell Significance Index: -0.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0064
    Cell Significance Index: -11.7900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0104
    Cell Significance Index: -0.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0113
    Cell Significance Index: -17.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0148
    Cell Significance Index: -11.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0242
    Cell Significance Index: -10.9800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0299
    Cell Significance Index: -22.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0384
    Cell Significance Index: -23.9800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0396
    Cell Significance Index: -53.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0596
    Cell Significance Index: -33.6000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1172
    Cell Significance Index: -11.9700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1176
    Cell Significance Index: -3.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1408
    Cell Significance Index: -29.6600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1664
    Cell Significance Index: -2.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1733
    Cell Significance Index: -20.2000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1811
    Cell Significance Index: -52.1100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2137
    Cell Significance Index: -31.0700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2307
    Cell Significance Index: -5.3300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2901
    Cell Significance Index: -8.5200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2904
    Cell Significance Index: -33.2700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3095
    Cell Significance Index: -1.8700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3719
    Cell Significance Index: -9.7800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3846
    Cell Significance Index: -10.3100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3985
    Cell Significance Index: -45.4900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4190
    Cell Significance Index: -7.1800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4299
    Cell Significance Index: -28.9100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4376
    Cell Significance Index: -8.5400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.5226
    Cell Significance Index: -4.3900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5240
    Cell Significance Index: -18.2100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5532
    Cell Significance Index: -57.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5539
    Cell Significance Index: -43.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5880
    Cell Significance Index: -26.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6725
    Cell Significance Index: -35.3100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6891
    Cell Significance Index: -22.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7019
    Cell Significance Index: -26.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7238
    Cell Significance Index: -44.3800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.7923
    Cell Significance Index: -16.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8722
    Cell Significance Index: -22.4200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.9950
    Cell Significance Index: -25.4200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.0049
    Cell Significance Index: -26.8800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.0134
    Cell Significance Index: -51.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.0317
    Cell Significance Index: -25.7900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -1.1112
    Cell Significance Index: -12.0800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1116
    Cell Significance Index: -32.7400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.1146
    Cell Significance Index: -20.6000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2779
    Cell Significance Index: -41.8400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.2851
    Cell Significance Index: -30.8200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2877
    Cell Significance Index: -47.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.3002
    Cell Significance Index: -41.4100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.3212
    Cell Significance Index: -28.9300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** COPB1 is a subunit of the COPI complex, which is composed of multiple subunits. The COPI complex is characterized by its ability to bind to target proteins and facilitate their transport between the ER and Golgi apparatus. COPB1 is specifically involved in retrograde transport, where it helps to return proteins from the Golgi apparatus back to the ER for modification or degradation. COPB1 is also involved in anterograde transport, where it facilitates the transport of proteins from the ER to the Golgi apparatus for modification and packaging. **Pathways and Functions** COPB1 is involved in several key pathways, including: 1. **Asparagine N-linked Glycosylation**: COPB1 helps to regulate the transport of proteins that undergo asparagine N-linked glycosylation, a post-translational modification that is essential for protein function. 2. **Copii-dependent Golgi-to-ER retrograde traffic**: COPB1 is involved in the retrograde transport of proteins from the Golgi apparatus back to the ER. 3. **Copii-mediated anterograde transport**: COPB1 facilitates the transport of proteins from the ER to the Golgi apparatus for modification and packaging. 4. **Intra-golgi and retrograde Golgi-to-ER traffic**: COPB1 is involved in the regulation of protein transport within the Golgi apparatus and its interaction with the ER. **Clinical Significance** Alterations in the COPB1 gene have been implicated in several diseases, including: 1. **Neutrophil degranulation disorders**: Mutations in COPB1 have been associated with neutrophil degranulation disorders, such as chronic granulomatous disease. 2. **Immune system disorders**: COPB1 is also involved in the regulation of immune responses, and alterations in the gene have been implicated in immune system disorders, such as autoimmune diseases. 3. **Cancer**: COPB1 has been implicated in the regulation of protein transport and modification, and alterations in the gene have been associated with cancer. 4. **Neurological disorders**: COPB1 has also been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, COPB1 is a critical component of the COPI complex, involved in regulating protein transport and modification within the Golgi apparatus and endoplasmic reticulum. Alterations in the COPB1 gene have been implicated in various diseases, highlighting its importance in maintaining cellular integrity and proper protein function. Further research is needed to fully understand the role of COPB1 in disease and to develop therapeutic strategies to target this gene in disease treatment.

Genular Protein ID: 3512341529

Symbol: COPB_HUMAN

Name: Coatomer subunit beta

UniProtKB Accession Codes:

P53618 D3DQX0 Q6GTT7 Q9NTK2 Q9UNW7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 2 PIRSF 1 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7982906

Title: Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.

PubMed ID: 7982906

DOI: 10.1016/s0021-9258(18)43773-8

PubMed ID: 7573041

Title: The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complex.

PubMed ID: 7573041

PubMed ID: 11056392

Title: Identification and characterization of novel isoforms of COP I subunits.

PubMed ID: 11056392

DOI: 10.1093/oxfordjournals.jbchem.a022817

PubMed ID: 11520457

Title: The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments.

PubMed ID: 11520457

DOI: 10.1016/s1074-7613(01)00179-0

PubMed ID: 12582157

Title: An essential function of tapasin in quality control of HLA-G molecules.

PubMed ID: 12582157

DOI: 10.1074/jbc.m212882200

PubMed ID: 17451557

Title: Multiple and stepwise interactions between coatomer and ADP-ribosylation factor-1 (Arf1)-GTP.

PubMed ID: 17451557

DOI: 10.1111/j.1600-0854.2007.00554.x

PubMed ID: 18385291

Title: Depletion of beta-COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1.

PubMed ID: 18385291

DOI: 10.1152/ajpcell.00010.2008

PubMed ID: 18556652

Title: Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

PubMed ID: 18556652

DOI: 10.1074/jbc.m801869200

PubMed ID: 18725938

Title: HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.

PubMed ID: 18725938

DOI: 10.1371/journal.ppat.1000131

PubMed ID: 18356299

Title: COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.

PubMed ID: 18356299

DOI: 10.1073/pnas.0710100105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19364919

Title: Early endosomes and endosomal coatomer are required for autophagy.

PubMed ID: 19364919

DOI: 10.1083/jcb.200810098

PubMed ID: 20362547

Title: Enhancement of TREK1 channel surface expression by protein-protein interaction with beta-COP.

PubMed ID: 20362547

DOI: 10.1016/j.bbrc.2010.03.171

PubMed ID: 20056612

Title: Quantitative proteomics analysis of cell cycle-regulated Golgi disassembly and reassembly.

PubMed ID: 20056612

DOI: 10.1074/jbc.m109.047084

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 24806965

Title: TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport.

PubMed ID: 24806965

DOI: 10.1242/jcs.136754

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30352685

Title: Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

PubMed ID: 30352685

DOI: 10.1016/j.bbrc.2018.10.073

PubMed ID: 33632302

Title: Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly.

PubMed ID: 33632302

DOI: 10.1186/s13073-021-00850-w

Sequence Information:

  • Length: 953
  • Mass: 107142
  • Checksum: BE916C1C5A599D79
  • Sequence:
    • MTAAENVCYT LINVPMDSEP PSEISLKNDL EKGDVKSKTE ALKKVIIMIL NGEKLPGLLM 
TIIRFVLPLQ DHTIKKLLLV FWEIVPKTTP DGRLLHEMIL VCDAYRKDLQ HPNEFIRGST 
LRFLCKLKEA ELLEPLMPAI RACLEHRHSY VRRNAVLAIY TIYRNFEHLI PDAPELIHDF 
LVNEKDASCK RNAFMMLIHA DQDRALDYLS TCIDQVQTFG DILQLVIVEL IYKVCHANPS 
ERARFIRCIY NLLQSSSPAV KYEAAGTLVT LSSAPTAIKA AAQCYIDLII KESDNNVKLI 
VLDRLIELKE HPAHERVLQD LVMDILRVLS TPDLEVRKKT LQLALDLVSS RNVEELVIVL 
KKEVIKTNNV SEHEDTDKYR QLLVRTLHSC SVRFPDMAAN VIPVLMEFLS DNNEAAAADV 
LEFVREAIQR FDNLRMLIVE KMLEVFHAIK SVKIYRGALW ILGEYCSTKE DIQSVMTEIR 
RSLGEIPIVE SEIKKEAGEL KPEEEITVGP VQKLVTEMGT YATQSALSSS RPTKKEEDRP 
PLRGFLLDGD FFVAASLATT LTKIALRYVA LVQEKKKQNS FVAEAMLLMA TILHLGKSSL 
PKKPITDDDV DRISLCLKVL SECSPLMNDI FNKECRQSLS HMLSAKLEEE KLSQKKESEK 
RNVTVQPDDP ISFMQLTAKN EMNCKEDQFQ LSLLAAMGNT QRKEAADPLA SKLNKVTQLT 
GFSDPVYAEA YVHVNQYDIV LDVLVVNQTS DTLQNCTLEL ATLGDLKLVE KPSPLTLAPH 
DFANIKANVK VASTENGIIF GNIVYDVSGA ASDRNCVVLS DIHIDIMDYI QPATCTDAEF 
RQMWAEFEWE NKVTVNTNMV DLNDYLQHIL KSTNMKCLTP EKALSGYCGF MAANLYARSI 
FGEDALANVS IEKPIHQGPD AAVTGHIRIR AKSQGMALSL GDKINLSQKK TSI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.