Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 435.6289
Cell Significance Index: -67.7600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 264.3475
Cell Significance Index: -67.0500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 157.9251
Cell Significance Index: -74.5600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 155.4445
Cell Significance Index: -64.0400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 150.0035
Cell Significance Index: -60.9400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 137.2901
Cell Significance Index: -70.6200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 63.8811
Cell Significance Index: -60.9900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 58.4206
Cell Significance Index: -72.0300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 25.1338
Cell Significance Index: -67.3300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 22.5952
Cell Significance Index: -69.4000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.5489
Cell Significance Index: -73.2000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.4046
Cell Significance Index: -40.2800 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 9.1892
Cell Significance Index: 81.5700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 9.0798
Cell Significance Index: 242.4500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 7.0628
Cell Significance Index: 197.3800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 4.2467
Cell Significance Index: 187.8400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.9158
Cell Significance Index: 148.2800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.5060
Cell Significance Index: 695.7800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.4959
Cell Significance Index: 268.2700 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 3.3876
Cell Significance Index: 20.9000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 3.3832
Cell Significance Index: 56.9900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 3.1060
Cell Significance Index: 1114.0500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.9268
Cell Significance Index: 62.5600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.8593
Cell Significance Index: 160.4500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.7855
Cell Significance Index: 558.7700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.5034
Cell Significance Index: 48.8600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.4634
Cell Significance Index: 1703.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.7975
Cell Significance Index: 110.4900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.6138
Cell Significance Index: 108.5100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.5136
Cell Significance Index: 36.3000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.4925
Cell Significance Index: 32.6800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.3402
Cell Significance Index: 34.4500 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.2287
Cell Significance Index: 15.2400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2171
Cell Significance Index: 120.4000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.0291
Cell Significance Index: 48.3700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.9801
Cell Significance Index: 27.9700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8916
Cell Significance Index: 109.6400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8773
Cell Significance Index: 792.1700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.7397
Cell Significance Index: 327.0600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6998
Cell Significance Index: 126.1600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6127
Cell Significance Index: 66.6400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.5340
Cell Significance Index: 1005.4000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.5283
Cell Significance Index: 12.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.5052
Cell Significance Index: 320.8700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5016
Cell Significance Index: 30.1200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3782
Cell Significance Index: 61.5100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.3758
Cell Significance Index: 6.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3365
Cell Significance Index: 183.7500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3039
Cell Significance Index: 467.8600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.2943
Cell Significance Index: 8.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2632
Cell Significance Index: 485.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2228
Cell Significance Index: 302.9400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1870
Cell Significance Index: 35.5900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1817
Cell Significance Index: 82.4700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1490
Cell Significance Index: 10.5400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0713
Cell Significance Index: 2.0600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0576
Cell Significance Index: 2.9900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0197
Cell Significance Index: 1.4700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0068
Cell Significance Index: 5.1800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0022
Cell Significance Index: 0.2600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0397
Cell Significance Index: -5.7600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0433
Cell Significance Index: -5.6000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0496
Cell Significance Index: -36.7700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0531
Cell Significance Index: -38.9100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0749
Cell Significance Index: -46.7800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0763
Cell Significance Index: -43.0200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0988
Cell Significance Index: -2.1400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1078
Cell Significance Index: -18.4000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1093
Cell Significance Index: -3.8400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1213
Cell Significance Index: -16.6600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1288
Cell Significance Index: -16.5100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1377
Cell Significance Index: -8.8800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1659
Cell Significance Index: -2.4500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1877
Cell Significance Index: -2.3400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2176
Cell Significance Index: -22.6600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2220
Cell Significance Index: -63.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2360
Cell Significance Index: -24.1100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2450
Cell Significance Index: -51.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3465
Cell Significance Index: -40.3800 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.3482
Cell Significance Index: -4.3900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.3495
Cell Significance Index: -15.8400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.3564
Cell Significance Index: -5.2600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3710
Cell Significance Index: -42.5100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.4382
Cell Significance Index: -30.3100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5276
Cell Significance Index: -24.6000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5367
Cell Significance Index: -61.2600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.6164
Cell Significance Index: -8.4100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.6193
Cell Significance Index: -39.0300 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.6323
Cell Significance Index: -7.9800 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.7190
Cell Significance Index: -3.1300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7615
Cell Significance Index: -60.3100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.7671
Cell Significance Index: -11.0200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.8142
Cell Significance Index: -17.2800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.8479
Cell Significance Index: -44.5200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8668
Cell Significance Index: -53.1400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.9086
Cell Significance Index: -12.1200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.9392
Cell Significance Index: -30.7500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.9430
Cell Significance Index: -13.5100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.9431
Cell Significance Index: -8.6900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.9533
Cell Significance Index: -18.8500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3820169466
Symbol: ADK_HUMAN
Name: Adenosine kinase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8577746
Title: Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases.
PubMed ID: 8577746
PubMed ID: 8917457
Title: Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species. High frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene.
PubMed ID: 8917457
PubMed ID: 9070863
Title: Cloning and expression of the adenosine kinase gene from rat and human tissues.
PubMed ID: 9070863
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19635462
Title: Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus.
PubMed ID: 19635462
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 9843365
Title: Structure of human adenosine kinase at 1.5-A resolution.
PubMed ID: 9843365
DOI: 10.1021/bi9815445
PubMed ID: 12112843
Title: Identification of the phosphotyrosine proteome from thrombin activated platelets.
PubMed ID: 12112843
DOI: 10.1002/1615-9861(200206)2:6<642::aid-prot642>3.0.co;2-i
PubMed ID: 21963049
Title: Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
PubMed ID: 21963049
Sequence Information:
- Length: 362
- Mass: 40545
- Checksum: 48AA4925865BFE70
- Sequence:
MAAAEEEPKP KKLKVEAPQA LRENILFGMG NPLLDISAVV DKDFLDKYSL KPNDQILAED KHKELFDELV KKFKVEYHAG GSTQNSIKVA QWMIQQPHKA ATFFGCIGID KFGEILKRKA AEAHVDAHYY EQNEQPTGTC AACITGDNRS LIANLAAANC YKKEKHLDLE KNWMLVEKAR VCYIAGFFLT VSPESVLKVA HHASENNRIF TLNLSAPFIS QFYKESLMKV MPYVDILFGN ETEAATFARE QGFETKDIKE IAKKTQALPK MNSKRQRIVI FTQGRDDTIM ATESEVTAFA VLDQDQKEII DTNGAGDAFV GGFLSQLVSD KPLTECIRAG HYAASIIIRR TGCTFPEKPD FH
Genular Protein ID: 913775614
Symbol: A0A5F9ZH72_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 229
- Mass: 25942
- Checksum: 4F72B2BE7E9DC2FE
- Sequence:
MTSVRENILF GMGNPLLDIS AVVDKDFLDK YSLKPNDQIL AEDKHKELFD ELVKKFKVEY HAGGSTQNSI KVAQWMIQQP HKAATFFGCI GIDKFGEILK RKAAEAHVDA HYYEQNEQPT GTCAACITGD NRSLIANLAA ANCYKKEKHL DLEKNWMLVE KARVCYIAGF FLTVSPESVL KVAHHASENN RIFTLNLSAP FISQFYKESL MKVMPYVDIL FGNETTYHI
Genular Protein ID: 3645166431
Symbol: A0A5F9ZHJ1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 270
- Mass: 30167
- Checksum: 50BEFE2973A11254
- Sequence:
MIQQPHKAAT FFGCIGIDKF GEILKRKAAE AHVDAHYYEQ NEQPTGTCAA CITGDNRSLI ANLAAANCYK KEKHLDLEKN WMLVEKARVC YIAGFFLTVS PESVLKVAHH ASENNRIFTL NLSAPFISQF YKESLMKVMP YVDILFGNET EAATFAREQG FETKDIKEIA KKTQALPKMN SKRQRIVIFT QGRDDTIMAT ESEVTAFAVL DQDQKEIIDT NGAGDAFVGG FLSQLVSDKP LTECIRAGHY AASIIIRRTG CTFPEKPDFH
Genular Protein ID: 2346542517
Symbol: A0A140VJE0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 345
- Mass: 38703
- Checksum: 7DC20F364E63D944
- Sequence:
MTSVRENILF GMGNPLLDIS AVVDKDFLDK YSLKPNDQIL AEDKHKELFD ELVKKFKVEY HAGGSTQNSI KVAQWMIQQP HKAATFFGCI GIDKFGEILK RKAAEAHVDA HYYEQNEQPT GTCAACITGD NRSLIANLAA ANCYKKEKHL DLEKNWMLVE KARVCYIAGF FLTVSPESVL KVAHHASENN RIFTLNLSAP FISQFYKESL MKVMPYVDIL FGNETEAATF AREQGFETKD IKEIAKKTQA LPKMNSKRQR IVIFTQGRDD TIMATESEVT AFAVLDQDQK EIIDTNGAGD AFVGGFLSQL VSDKPLTECI RAGHYAASII IRRTGCTFPE KPDFH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.