Genular: Defining Cellular Identity and Function

Details for: Ddx6

Gene ID: 13209

Symbol: Ddx6

Ensembl ID: ENSMUSG00000032097

Description: DEAD-box helicase 6

Associated with

Deadenylation-dependent mrna decay
(R-MMU-429914)
Metabolism of rna
(R-MMU-8953854)
Mrna decay by 5' to 3' exoribonuclease
(R-MMU-430039)
Adherens junction
(GO:0005912)
Atp binding
(GO:0005524)
Chromatoid body
(GO:0033391)
Concave side of sperm head
(GO:0061830)
Cytoplasm
(GO:0005737)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytoplasmic stress granule
(GO:0010494)
Cytosol
(GO:0005829)
Helicase activity
(GO:0004386)
Heterochromatin
(GO:0000792)
Hydrolase activity
(GO:0016787)
Mirna-mediated gene silencing by inhibition of translation
(GO:0035278)
Mrna binding
(GO:0003729)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of translation
(GO:0017148)
Neuron differentiation
(GO:0030182)
Nucleic acid binding
(GO:0003676)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Outer dense fiber
(GO:0001520)
P-body
(GO:0000932)
P-body assembly
(GO:0033962)
Perinuclear region of cytoplasm
(GO:0048471)
Protein domain specific binding
(GO:0019904)
Risc complex
(GO:0016442)
Rna binding
(GO:0003723)
Rna helicase activity
(GO:0003724)
Sperm annulus
(GO:0097227)
Stem cell population maintenance
(GO:0019827)
Stress granule assembly
(GO:0034063)
Viral rna genome packaging
(GO:0019074)

Other Information

Proteins

ATP-dependent RNA helicase p54

Genular Protein ID: 340138080

Symbol: DDX6_MOUSE

Name: ATP-dependent RNA helicase p54

UniProtKB Accession Codes:

P54823 O54979 Q3UFI3 Q8BW68

Database IDs:

Citations:

PubMed ID: 8543178

Title: Cloning and expression of a murine cDNA homologous to the human RCK/P54, a lymphoma-linked chromosomal translocation junction gene on 11q23.

PubMed ID: 8543178

DOI: 10.1016/0378-1119(95)00559-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9883581

Title: RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.

PubMed ID: 9883581

DOI: 10.1002/(sici)1520-6408(1998)23:4<285::aid-dvg4>3.0.co;2-w

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20639877

Title: Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.

PubMed ID: 20639877

DOI: 10.1038/ni.1902

PubMed ID: 26098573

Title: A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy.

PubMed ID: 26098573

DOI: 10.1038/ncb3189

Sequence Information:

Length: 483
Mass: 54192
Checksum: 9AD22D171F8BC14D
Sequence:

MSTARTENPV IMGLSSQNGQ LRGPVKASAG PGGGGTQPQP QLNQLKNTST INNGTPQQAQ 
SMAATIKPGD DWKKTLKLPP KDLRIKTSDV TSTKGNEFED YCLKRELLMG IFEMGWEKPS 
PIQEESIPIA LSGRDILARA KNGTGKSGAY LIPLLERLDL KKDNIQAMVI VPTRELALQV 
SQICIQVSKH MGGAKVMATT GGTNLRDDIM RLDDTVHVVI ATPGRILDLI KKGVAKVDHV 
QMIVLDEADK LLSQDFVQIM EDIILTLPKN RQILLYSATF PLSVQKFMNS HLQKPYEINL 
MEELTLKGVT QYYAYVTERQ KVHCLNTLFS RLQINQSIIF CNSSQRVELL AKKISQLGYS 
CFYIHAKMRQ EHRNRVFHDF RNGLCRNLVC TDLFTRGIDI QAVNVVINFD FPKLAETYLH 
RIGRSGRFGH LGLAINLITY DDRFNLKSIE EQLGTEIKPI PSNIDKSLYV AEYHSEPAED 
EKP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ddx6

Associated with

Other Information

Cloning and expression of a murine cDNA homologous to the human RCK/P54, a lymphoma-linked chromosomal translocation junction gene on 11q23. PubMed ID: 8543178

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins. PubMed ID: 9883581

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. PubMed ID: 20639877

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy. PubMed ID: 26098573