Genular: Defining Cellular Identity and Function

Details for: Defb1

Gene ID: 13214

Symbol: Defb1

Ensembl ID: ENSMUSG00000044748

Description: defensin beta 1

Associated with

Antimicrobial peptides
(R-MMU-6803157)
Beta defensins
(R-MMU-1461957)
Defensins
(R-MMU-1461973)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Antibacterial humoral response
(GO:0019731)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Calcium-mediated signaling using intracellular calcium source
(GO:0035584)
Camp-mediated signaling
(GO:0019933)
Ccr6 chemokine receptor binding
(GO:0031731)
Defense response
(GO:0006952)
Defense response to bacterium
(GO:0042742)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Innate immune response in mucosa
(GO:0002227)
Membrane
(GO:0016020)
Microvesicle
(GO:1990742)
Positive regulation of flagellated sperm motility involved in capacitation
(GO:0060474)
Response to bacterium
(GO:0009617)
Sperm midpiece
(GO:0097225)

Other Information

Proteins

Beta-defensin 1

Genular Protein ID: 1991199530

Symbol: DEFB1_MOUSE

Name: Beta-defensin 1

UniProtKB Accession Codes:

P56386

Database IDs:

Citations:

PubMed ID: 9287114

Title: The mouse genome encodes a single homolog of the antimicrobial peptide human beta-defensin 1.

PubMed ID: 9287114

DOI: 10.1016/s0014-5793(97)00875-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10922379

Title: A novel murine beta-defensin expressed in tongue, esophagus, and trachea.

PubMed ID: 10922379

DOI: 10.1074/jbc.m006603200

Sequence Information:

Length: 69
Mass: 7749
Checksum: 8B12DBD3BBF3ACE4
Sequence:

MKTHYFLLVM ICFLFSQMEP GVGILTSLGR RTDQYKCLQH GGFCLRSSCP SNTKLQGTCK 
PDKPNCCKS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.