Genular: Defining Cellular Identity and Function

Details for: Defa3

Gene ID: 13237

Symbol: Defa3

Ensembl ID: ENSMUSG00000074440

Description: defensin, alpha, 3

Associated with

Alpha-defensins
(R-MMU-1462054)
Antimicrobial peptides
(R-MMU-6803157)
Defensins
(R-MMU-1461973)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Antibacterial humoral response
(GO:0019731)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Cellular response to lipopolysaccharide
(GO:0071222)
Defense response to bacterium
(GO:0042742)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Disruption of plasma membrane integrity in another organism
(GO:0051673)
Extracellular space
(GO:0005615)
Innate immune response in mucosa
(GO:0002227)
Intracellular membrane-bounded organelle
(GO:0043231)
Midbody
(GO:0030496)
Pore-forming activity
(GO:0140911)
Protein homodimerization activity
(GO:0042803)
Response to xenobiotic stimulus
(GO:0009410)
Secretory granule
(GO:0030141)

Other Information

Proteins

Alpha-defensin 3

Genular Protein ID: 3621359584

Symbol: DEFA3_MOUSE

Name: Alpha-defensin 3

UniProtKB Accession Codes:

P28310 Q499K7

Database IDs:

Citations:

PubMed ID: 8188287

Title: Structure and diversity of the murine cryptdin gene family.

PubMed ID: 8188287

DOI: 10.1006/geno.1994.1093

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1500431

Title: Enteric defensins: antibiotic peptide components of intestinal host defense.

PubMed ID: 1500431

DOI: 10.1083/jcb.118.4.929

Sequence Information:

Length: 93
Mass: 10528
Checksum: 2B2D61CFCF40E634
Sequence:

MKTLVLLSAL VLLAFQVQAD PIQNTDEETK TEEQPGEDDQ AVSVSFGDPE GSSLQEESLR 
DLVCYCRKRG CKRRERMNGT CRKGHLMYTL CCR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.