Genular: Defining Cellular Identity and Function

Details for: Defa6

Gene ID: 13240

Symbol: Defa6

Description: defensin, alpha, 6

Associated with

Antibacterial humoral response
(GO:0019731)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Cellular response to lipopolysaccharide
(GO:0071222)
Defense response
(GO:0006952)
Defense response to bacterium
(GO:0042742)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Disruption of plasma membrane integrity in another organism
(GO:0051673)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Innate immune response in mucosa
(GO:0002227)
Intracellular membrane-bounded organelle
(GO:0043231)
Midbody
(GO:0030496)
Pore-forming activity
(GO:0140911)
Protein homodimerization activity
(GO:0042803)
Response to xenobiotic stimulus
(GO:0009410)
Secretory granule
(GO:0030141)

Other Information

Proteins

Alpha-defensin 6/12

Genular Protein ID: 3549920417

Symbol: DEFA6_MOUSE

Name: Alpha-defensin 6/12

UniProtKB Accession Codes:

P50704 P50710 P82294

Database IDs:

Citations:

PubMed ID: 8188287

Title: Structure and diversity of the murine cryptdin gene family.

PubMed ID: 8188287

DOI: 10.1006/geno.1994.1093

PubMed ID: 7927786

Title: Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.

PubMed ID: 7927786

DOI: 10.1128/iai.62.11.5040-5047.1994

PubMed ID: 1500163

Title: Cryptdins: antimicrobial defensins of the murine small intestine.

PubMed ID: 1500163

DOI: 10.1128/iai.60.9.3556-3565.1992

Sequence Information:

Length: 93
Mass: 10426
Checksum: 84CE684E476FB885
Sequence:

MKTLILLSAL VLLAFQVQAD PIQNTDEETK TEEQPGEEDQ AVSVSFGDPE GTSLQEESLR 
DLVCYCRARG CKGRERMNGT CRKGHLLYML CCR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.