Genular: Defining Cellular Identity and Function

Details for: Degs1

Gene ID: 13244

Symbol: Degs1

Ensembl ID: ENSMUSG00000038633

Description: delta 4-desaturase, sphingolipid 1

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Neutrophil degranulation
(R-MMU-6798695)
Sphingolipid de novo biosynthesis
(R-MMU-1660661)
Sphingolipid metabolism
(R-MMU-428157)
Ceramide biosynthetic process
(GO:0046513)
Endoplasmic reticulum
(GO:0005783)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Isomerase activity
(GO:0016853)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Myelin maintenance
(GO:0043217)
Oxidoreductase activity
(GO:0016491)
Positive regulation of apoptotic process
(GO:0043065)
Retinol isomerase activity
(GO:0050251)
Sphingolipid biosynthetic process
(GO:0030148)
Sphingolipid delta-4 desaturase activity
(GO:0042284)

Other Information

Proteins

Degenerative spermatocyte homolog 1

Genular Protein ID: 4089821777

Symbol: DEGS1_MOUSE

Name: Degenerative spermatocyte homolog 1

UniProtKB Accession Codes:

O09005 Q8R4H3

Database IDs:

Citations:

PubMed ID: 9227906

Title: Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis.

PubMed ID: 9227906

DOI: 10.1046/j.1440-169x.1997.00015.x

PubMed ID: 11937514

Title: Identification and characterization of a sphingolipid delta 4-desaturase family.

PubMed ID: 11937514

DOI: 10.1074/jbc.m202947200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23143414

Title: Identification of DES1 as a vitamin A isomerase in Mueller glial cells of the retina.

PubMed ID: 23143414

DOI: 10.1038/nchembio.1114

Sequence Information:

Length: 323
Mass: 38241
Checksum: C1840C24E6FF29E0
Sequence:

MGSRVSREEF EWVYTDQPHA ARRKEILAKY PEIKSLMKPD HNLIWIVAMM LLVQLASFYL 
VKDLDWKWVI FWSYVFGSCL NHSMTLAIHE ISHNFPFGHH KALWNRWFGM FANLSLGVPY 
SISFKRYHMD HHRYLGADKI DVDIPTDFEG WFFCTTFRKF VWVILQPLFY AFRPLFINPK 
PITYLEIINT VIQITFDIII YYVFGVKSLV YMLAATLLGL GLHPISGHFI AEHYMFLKGH 
ETYSYYGPLN LLTFNVGYHN EHHDFPNVPG KNLPMVRKIA SEYYDDLPHY NSWIKVLYDF 
VTDDTISPYS RMKRPPKGNE ILE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Degs1

Associated with

Other Information

Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis. PubMed ID: 9227906

Identification and characterization of a sphingolipid delta 4-desaturase family. PubMed ID: 11937514

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079