Details for: COX4I1

Gene ID: 1327

Symbol: COX4I1

Ensembl ID: ENSG00000131143

Description: cytochrome c oxidase subunit 4I1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 950.5274
    Cell Significance Index: -147.8500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 526.6844
    Cell Significance Index: -133.5900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 463.6026
    Cell Significance Index: -190.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 441.1246
    Cell Significance Index: -179.2100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 391.0425
    Cell Significance Index: -184.6200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 375.9828
    Cell Significance Index: -193.4000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 277.1406
    Cell Significance Index: -185.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 191.2243
    Cell Significance Index: -182.5700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 138.6424
    Cell Significance Index: -170.9400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 47.0884
    Cell Significance Index: -144.6300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 46.8722
    Cell Significance Index: -184.9600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 29.9605
    Cell Significance Index: -80.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 26.5559
    Cell Significance Index: -58.1200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 8.5318
    Cell Significance Index: 228.2200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 7.9427
    Cell Significance Index: 417.0200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 7.2608
    Cell Significance Index: 341.2500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 7.0345
    Cell Significance Index: 162.5200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 6.6089
    Cell Significance Index: 308.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 5.9562
    Cell Significance Index: 769.5000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 5.5589
    Cell Significance Index: 1002.1000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 5.5243
    Cell Significance Index: 390.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 5.3907
    Cell Significance Index: 662.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 5.3645
    Cell Significance Index: 141.0600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 5.2222
    Cell Significance Index: 96.5200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 5.0223
    Cell Significance Index: 689.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.9775
    Cell Significance Index: 2718.3500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 4.9243
    Cell Significance Index: 2177.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 4.8219
    Cell Significance Index: 359.3700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.7035
    Cell Significance Index: 128.0300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.6485
    Cell Significance Index: 136.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 4.4830
    Cell Significance Index: 528.6800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 4.1486
    Cell Significance Index: 47.1300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.1206
    Cell Significance Index: 37.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.8984
    Cell Significance Index: 251.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 3.3577
    Cell Significance Index: 332.1500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 3.2423
    Cell Significance Index: 57.3000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 3.0268
    Cell Significance Index: 137.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.9431
    Cell Significance Index: 102.2700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 2.9362
    Cell Significance Index: 18.0700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.2948
    Cell Significance Index: 119.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.1840
    Cell Significance Index: 279.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.0122
    Cell Significance Index: 343.5900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.9229
    Cell Significance Index: 40.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.6769
    Cell Significance Index: 48.0700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.5924
    Cell Significance Index: 42.5200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4162
    Cell Significance Index: 73.7700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2070
    Cell Significance Index: 196.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.8958
    Cell Significance Index: 656.8000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7149
    Cell Significance Index: 141.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6993
    Cell Significance Index: 140.2800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6498
    Cell Significance Index: 123.6600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.6079
    Cell Significance Index: 460.1200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5208
    Cell Significance Index: 470.2300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.3291
    Cell Significance Index: 4.2200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1879
    Cell Significance Index: 2.2400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0779
    Cell Significance Index: 27.9300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0185
    Cell Significance Index: 0.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.0044
    Cell Significance Index: 0.3500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0328
    Cell Significance Index: -61.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0384
    Cell Significance Index: -3.9300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0591
    Cell Significance Index: -43.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0948
    Cell Significance Index: -174.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1167
    Cell Significance Index: -179.6300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1451
    Cell Significance Index: -197.2600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1607
    Cell Significance Index: -100.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.2253
    Cell Significance Index: -143.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2305
    Cell Significance Index: -130.0100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3219
    Cell Significance Index: -9.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.3298
    Cell Significance Index: -149.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3302
    Cell Significance Index: -20.8100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3857
    Cell Significance Index: -5.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3948
    Cell Significance Index: -83.1600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4819
    Cell Significance Index: -28.9300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.5482
    Cell Significance Index: -157.7500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.8091
    Cell Significance Index: -20.6700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.8187
    Cell Significance Index: -8.9000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8308
    Cell Significance Index: -95.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8876
    Cell Significance Index: -28.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.0986
    Cell Significance Index: -128.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -1.1015
    Cell Significance Index: -160.1200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.1344
    Cell Significance Index: -129.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.1387
    Cell Significance Index: -24.6700
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.4038
    Cell Significance Index: -24.2000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.4193
    Cell Significance Index: -108.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.4769
    Cell Significance Index: -90.7800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.5718
    Cell Significance Index: -12.5500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.7420
    Cell Significance Index: -181.3800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.8546
    Cell Significance Index: -104.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.9440
    Cell Significance Index: -68.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -2.1743
    Cell Significance Index: -146.2000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -2.2212
    Cell Significance Index: -13.4200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -2.3645
    Cell Significance Index: -32.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.6799
    Cell Significance Index: -164.3000
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -3.1445
    Cell Significance Index: -65.5800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -3.2112
    Cell Significance Index: -80.2700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -3.2263
    Cell Significance Index: -55.2900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -3.2976
    Cell Significance Index: -95.0100
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -3.6157
    Cell Significance Index: -31.0700
  • Cell Name: theca cell (CL0000503)
    Fold Change: -3.6885
    Cell Significance Index: -21.6700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -3.7000
    Cell Significance Index: -108.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** COX4I1 is a mitochondrial protein that plays a pivotal role in the electron transport chain, specifically in the transfer of electrons from cytochrome c to oxygen. This process is essential for the production of ATP, the primary energy currency of the cell. COX4I1 is also involved in the regulation of cellular responses to stress, including hypoxia, oxidative stress, and chemical stress. Its expression is tightly regulated by various transcription factors, including TP53, which is a tumor suppressor protein. **Pathways and Functions:** COX4I1 is integrated into multiple signaling pathways, including: 1. **Cellular respiration:** COX4I1 is a key component of the mitochondrial respiratory chain complex IV, responsible for the transfer of electrons from cytochrome c to oxygen, generating ATP. 2. **Stress response:** COX4I1 is involved in the regulation of cellular responses to stress, including hypoxia, oxidative stress, and chemical stress. 3. **Gene expression:** COX4I1 is regulated by various transcription factors, including TP53, which is a critical regulator of metabolic genes. 4. **Protein degradation:** COX4I1 is involved in the regulation of mitochondrial protein degradation, which is essential for maintaining mitochondrial function and preventing cellular stress. **Clinical Significance:** Dysregulation of COX4I1 has been implicated in various disease states, including: 1. **Cancer:** Overexpression of COX4I1 has been observed in various types of cancer, including leukemia, lymphoma, and breast cancer. 2. **Neurodegenerative diseases:** Alterations in COX4I1 expression have been linked to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Cardiovascular disease:** COX4I1 has been implicated in the regulation of cardiovascular function, and its dysregulation has been linked to cardiovascular disease. 4. **Immune dysregulation:** COX4I1 is expressed in immune cells, and its dysregulation has been linked to immune dysregulation and autoimmune diseases. In conclusion, COX4I1 is a critical component of the mitochondrial respiratory chain complex IV, involved in the regulation of cellular responses to stress and the production of ATP. Its dysregulation has been implicated in various disease states, highlighting the importance of COX4I1 in maintaining cellular homeostasis and preventing disease. Further research is needed to fully elucidate the role of COX4I1 in human disease.

Genular Protein ID: 2422795391

Symbol: COX41_HUMAN

Name: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2444497

Title: Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase.

PubMed ID: 2444497

DOI: 10.1016/0378-1119(87)90281-2

PubMed ID: 2157630

Title: Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV.

PubMed ID: 2157630

DOI: 10.1016/0378-1119(90)90281-u

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10337626

Title: The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4.

PubMed ID: 10337626

DOI: 10.1007/s003359901031

PubMed ID: 1311608

Title: Subunit IV of human cytochrome c oxidase, polymorphism and a putative isoform.

PubMed ID: 1311608

DOI: 10.1016/0167-4838(92)90395-t

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26759378

Title: The mammalian homologue of yeast Afg1 ATPase (lactation elevated 1) mediates degradation of nuclear-encoded complex IV subunits.

PubMed ID: 26759378

DOI: 10.1042/bj20151029

PubMed ID: 28766551

Title: Mutation in the COX4I1 gene is associated with short stature, poor weight gain and increased chromosomal breaks, simulating Fanconi anemia.

PubMed ID: 28766551

DOI: 10.1038/ejhg.2017.112

PubMed ID: 31290619

Title: Biallelic variants in COX4I1 associated with a novel phenotype resembling Leigh syndrome with developmental regression, intellectual disability, and seizures.

PubMed ID: 31290619

DOI: 10.1002/ajmg.a.61288

PubMed ID: 28844695

Title: Architecture of human mitochondrial respiratory megacomplex I2III2IV2.

PubMed ID: 28844695

DOI: 10.1016/j.cell.2017.07.050

PubMed ID: 30030519

Title: Structure of the intact 14-subunit human cytochrome c oxidase.

PubMed ID: 30030519

DOI: 10.1038/s41422-018-0071-1

Sequence Information:

  • Length: 169
  • Mass: 19577
  • Checksum: F6382FFDCF3BE4ED
  • Sequence:
  • MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK 
    ALKEKEKASW SSLSMDEKVE LYRIKFKESF AEMNRGSNEW KTVVGGAMFF IGFTALVIMW 
    QKHYVYGPLP QSFDKEWVAK QTKRMLDMKV NPIQGLASKW DYEKNEWKK

Genular Protein ID: 2226600151

Symbol: Q86WV2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 83
  • Mass: 9291
  • Checksum: 8DB8AE40FDAE8909
  • Sequence:
  • MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK 
    ALKEKEKASW SSLSMDEKVE CGY

Genular Protein ID: 1621839967

Symbol: H3BNV9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 139
  • Mass: 15725
  • Checksum: 13EBD2AFE2084F8C
  • Sequence:
  • MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK 
    ALKEKEKASW SSLSMDEKVE LYRIKFKESF AEMNRGSNEW KTVVGGAMFF IGFTALVIMW 
    QKHYGHLGLC LSDPVIHSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.