ADM | ENSG00000148926 | NCBI 133

Details for: ADM

Gene ID: 133

Symbol: ADM

Ensembl ID: ENSG00000148926

Description: adrenomedullin

Associated with

Calcitonin-like ligand receptors
(R-HSA-419812)
Class b/2 (secretin family receptors)
(R-HSA-373080)
G alpha (s) signalling events
(R-HSA-418555)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Signaling by gpcr
(R-HSA-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adrenomedullin receptor binding
(GO:0031700)
Adrenomedullin receptor signaling pathway
(GO:1990410)
Androgen metabolic process
(GO:0008209)
Animal organ regeneration
(GO:0031100)
Branching involved in labyrinthine layer morphogenesis
(GO:0060670)
Camp-mediated signaling
(GO:0019933)
Cell population proliferation
(GO:0008283)
Cytoplasm
(GO:0005737)
Developmental growth
(GO:0048589)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Female pregnancy
(GO:0007565)
G protein-coupled receptor internalization
(GO:0002031)
Heart development
(GO:0007507)
Hormone activity
(GO:0005179)
Inflammatory response
(GO:0006954)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of vascular permeability
(GO:0043116)
Negative regulation of vasoconstriction
(GO:0045906)
Neural tube closure
(GO:0001843)
Neuron projection regeneration
(GO:0031102)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of heart rate
(GO:0010460)
Positive regulation of progesterone biosynthetic process
(GO:2000184)
Positive regulation of vasculogenesis
(GO:2001214)
Receptor internalization
(GO:0031623)
Regulation of systemic arterial blood pressure
(GO:0003073)
Regulation of the force of heart contraction
(GO:0002026)
Regulation of urine volume
(GO:0035809)
Response to glucocorticoid
(GO:0051384)
Response to hypoxia
(GO:0001666)
Response to insulin
(GO:0032868)
Response to lipopolysaccharide
(GO:0032496)
Response to starvation
(GO:0042594)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Vascular associated smooth muscle cell development
(GO:0097084)
Vasculogenesis
(GO:0001570)

Other Information

Proteins

Pro-adrenomedullin

Genular Protein ID: 1017360539

Symbol: ADML_HUMAN

Name: Pro-adrenomedullin

UniProtKB Accession Codes:

P35318 B2R793 D3DQV3 Q6FGW2

Database IDs:

Citations:

PubMed ID: 7688224

Title: Cloning and characterization of cDNA encoding a precursor for human adrenomedullin.

PubMed ID: 7688224

DOI: 10.1006/bbrc.1993.1881

PubMed ID: 8074714

Title: Genomic structure of human adrenomedullin gene.

PubMed ID: 8074714

DOI: 10.1006/bbrc.1994.2229

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8387282

Title: Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma.

PubMed ID: 8387282

DOI: 10.1006/bbrc.1993.1451

PubMed ID: 9578982

Title: Proadrenomedullin-derived peptides.

PubMed ID: 9578982

DOI: 10.1006/frne.1998.0164

PubMed ID: 10588445

Title: Structure-activity relationships of adrenomedullin in the circulation and adrenal gland.

PubMed ID: 10588445

DOI: 10.1016/s0167-0115(99)00025-7

PubMed ID: 16315141

Title: NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth.

PubMed ID: 16315141

DOI: 10.1002/bip.20418

Sequence Information:

Length: 185
Mass: 20420
Checksum: 64C7D2A0B4654DFE
Sequence:

MKLVSVALMY LGSLAFLGAD TARLDVASEF RKKWNKWALS RGKRELRMSS SYPTGLADVK 
AGPAQTLIRP QDMKGASRSP EDSSPDAARI RVKRYRQSMN NFQGLRSFGC RFGTCTVQKL 
AHQIYQFTDK DKDNVAPRSK ISPQGYGRRR RRSLPEAGPG RTLVSSKPQA HGAPAPPSGS 
APHFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ADM

Associated with

Other Information

Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. PubMed ID: 7688224

Genomic structure of human adrenomedullin gene. PubMed ID: 8074714

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. PubMed ID: 8387282

Proadrenomedullin-derived peptides. PubMed ID: 9578982

Structure-activity relationships of adrenomedullin in the circulation and adrenal gland. PubMed ID: 10588445

NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth. PubMed ID: 16315141