Associated with
Other Information
Genular Protein ID: 1513998423
Symbol: DESM_MOUSE
Name: Desmin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8120103
Title: Inhibition of desmin expression blocks myoblast fusion and interferes with the myogenic regulators MyoD and myogenin.
PubMed ID: 8120103
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8382796
Title: Regulation of the mouse desmin gene: transactivated by MyoD, myogenin, MRF4 and Myf5.
PubMed ID: 8382796
DOI: 10.1093/nar/21.2.335
PubMed ID: 10357897
Title: Dystonin-deficient mice exhibit an intrinsic muscle weakness and an instability of skeletal muscle cytoarchitecture.
PubMed ID: 10357897
PubMed ID: 10852826
Title: Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.
PubMed ID: 10852826
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 24940650
Title: Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.
PubMed ID: 24940650
DOI: 10.1038/jid.2014.255
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25394388
Title: The toxic effect of R350P mutant desmin in striated muscle of man and mouse.
PubMed ID: 25394388
PubMed ID: 26343497
Title: The E3 ubiquitin ligase Asb2beta is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
PubMed ID: 26343497
PubMed ID: 27565725
Title: Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.
PubMed ID: 27565725
PubMed ID: 26787680
Title: Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene.
PubMed ID: 26787680
DOI: 10.1242/bio.014993
PubMed ID: 27733623
Title: Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts.
PubMed ID: 27733623
PubMed ID: 27102488
Title: Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes.
PubMed ID: 27102488
PubMed ID: 28469177
Title: Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice.
PubMed ID: 28469177
Sequence Information:
- Length: 469
- Mass: 53498
- Checksum: 58A8A13C7CC11EEF
- Sequence:
MSQAYSSSQR VSSYRRTFGG APGFSLGSPL SSPVFPRAGF GTKGSSSSMT SRVYQVSRTS GGAGGLGSLR SSRLGTTRAP SYGAGELLDF SLADAVNQEF LATRTNEKVE LQELNDRFAN YIEKVRFLEQ QNAALAAEVN RLKGREPTRV AELYEEEMRE LRRQVEVLTN QRARVDVERD NLIDDLQRLK AKLQEEIQLR EEAENNLAAF RADVDAATLA RIDLERRIES LNEEIAFLKK VHEEEIRELQ AQLQEQQVQV EMDMSKPDLT AALRDIRAQY ETIAAKNISE AEEWYKSKVS DLTQAANKNN DALRQAKQEM MEYRHQIQSY TCEIDALKGT NDSLMRQMRE LEDRFASEAN GYQDNIARLE EEIRHLKDEM ARHLREYQDL LNVKMALDVE IATYRKLLEG EESRINLPIQ TFSALNFRET SPEQRGSEVH TKKTVMIKTI ETRDGEVVSE ATQQQHEVL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.