Details for: Diaph1
Associated with
Other Information
Genular Protein ID: 2323463486
Symbol: DIAP1_MOUSE
Name: Protein diaphanous homolog 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9214622
Title: p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.
PubMed ID: 9214622
PubMed ID: 10814512
Title: Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2.
PubMed ID: 10814512
PubMed ID: 10678165
Title: Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling.
PubMed ID: 10678165
PubMed ID: 15311282
Title: EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.
PubMed ID: 15311282
DOI: 10.1038/ncb1160
PubMed ID: 15044801
Title: Actin polymerization-driven molecular movement of mDia1 in living cells.
PubMed ID: 15044801
PubMed ID: 16452087
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
PubMed ID: 16452087
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 18572016
Title: Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1.
PubMed ID: 18572016
PubMed ID: 19350017
Title: SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
PubMed ID: 19350017
DOI: 10.1038/ncb1862
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23558171
Title: Nuclear actin network assembly by formins regulates the SRF coactivator MAL.
PubMed ID: 23558171
PubMed ID: 24781755
Title: Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans.
PubMed ID: 24781755
DOI: 10.1038/ejhg.2014.82
PubMed ID: 27808407
Title: Extension of the clinical and molecular phenotype of DIAPH1-associated autosomal dominant hearing loss (DFNA1).
PubMed ID: 27808407
DOI: 10.1111/cge.12915
PubMed ID: 14992721
Title: The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization.
PubMed ID: 14992721
PubMed ID: 16292343
Title: The regulation of mDia1 by autoinhibition and its release by Rho*GTP.
PubMed ID: 16292343
PubMed ID: 15864301
Title: Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
PubMed ID: 15864301
DOI: 10.1038/nature03604
Sequence Information:
- Length: 1255
- Mass: 139343
- Checksum: 09404164873CA7C1
- Sequence:
MEPSGGGLGP GRGTRDKKKG RSPDELPATG GDGGKHKKFL ERFTSMRIKK EKEKPNSAHR NSSASYGDDP TAQSLQDISD EQVLVLFEQM LVDMNLNEEK QQPLREKDIV IKREMVSQYL HTSKAGMNQK ESSRSAMMYI QELRSGLRDM HLLSCLESLR VSLNNNPVSW VQTFGAEGLA SLLDILKRLH DEKEETSGNY DSRNQHEIIR CLKAFMNNKF GIKTMLETEE GILLLVRAMD PAVPNMMIDA AKLLSALCIL PQPEDMNERV LEAMTERAEM DEVERFQPLL DGLKSGTSIA LKVGCLQLIN ALITPAEELD FRVHIRSELM RLGLHQVLQE LREIENEDMK VQLCVFDEQG DEDFFDLKGR LDDIRMEMDD FGEVFQIILN TVKDSKAEPH FLSILQHLLL VRNDYEARPQ YYKLIEECVS QIVLHKNGTD PDFKCRHLQI DIERLVDQMI DKTKVEKSEA KATELEKKLD SELTARHELQ VEMKKMENDF EQKLQDLQGE KDALDSEKQQ ITAQKQDLEA EVSKLTGEVA KLSKELEDAK NEMASLSAVV VAPSVSSSAA VPPAPPLPGD SGTVIPPPPP PPPLPGGVVP PSPPLPPGTC IPPPPPLPGG ACIPPPPQLP GSAAIPPPPP LPGVASIPPP PPLPGATAIP PPPPLPGATA IPPPPPLPGG TGIPPPPPPL PGSVGVPPPP PLPGGPGLPP PPPPFPGAPG IPPPPPGMGV PPPPPFGFGV PAAPVLPFGL TPKKVYKPEV QLRRPNWSKF VAEDLSQDCF WTKVKEDRFE NNELFAKLTL AFSAQTKTSK AKKDQEGGEE KKSVQKKKVK ELKVLDSKTA QNLSIFLGSF RMPYQEIKNV ILEVNEAVLT ESMIQNLIKQ MPEPEQLKML SELKEEYDDL AESEQFGVVM GTVPRLRPRL NAILFKLQFS EQVENIKPEI VSVTAACEEL RKSENFSSLL ELTLLVGNYM NAGSRNAGAF GFNISFLCKL RDTKSADQKM TLLHFLAELC ENDHPEVLKF PDELAHVEKA SRVSAENLQK SLDQMKKQIA DVERDVQNFP AATDEKDKFV EKMTSFVKDA QEQYNKLRMM HSNMETLYKE LGDYFVFDPK KLSVEEFFMD LHNFRNMFLQ AVKENQKRRE TEEKMRRAKL AKEKAEKERL EKQQKREQLI DMNAEGDETG VMDSLLEALQ SGAAFRRKRG PRQVNRKAGC AVTSLLASEL TKDDAMAPGP VKVPKKSEGV PTILEEAKEL VGRAS
Genular Protein ID: 1542964929
Symbol: E9PV41_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16452087
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
PubMed ID: 16452087
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1264
- Mass: 140402
- Checksum: 57194133AAE494A1
- Sequence:
MEPSGGGLGP GRGTRDKKKG RSPDELPATG GDGGKHKKFT LKRLMADELE RFTSMRIKKE KEKPNSAHRN SSASYGDDPT AQSLQDISDE QVLVLFEQML VDMNLNEEKQ QPLREKDIVI KREMVSQYLH TSKAGMNQKE SSRSAMMYIQ ELRSGLRDMH LLSCLESLRV SLNNNPVSWV QTFGAEGLAS LLDILKRLHD EKEETSGNYD SRNQHEIIRC LKAFMNNKFG IKTMLETEEG ILLLVRAMDP AVPNMMIDAA KLLSALCILP QPEDMNERVL EAMTERAEMD EVERFQPLLD GLKSGTSIAL KVGCLQLINA LITPAEELDF RVHIRSELMR LGLHQVLQEL REIENEDMKV QLCVFDEQGD EDFFDLKGRL DDIRMEMDDF GEVFQIILNT VKDSKAEPHF LSILQHLLLV RNDYEARPQY YKLIEECVSQ IVLHKNGTDP DFKCRHLQID IERLVDQMID KTKVEKSEAK ATELEKKLDS ELTARHELQV EMKKMENDFE QKLQDLQGEK DALDSEKQQI TAQKQDLEAE VSKLTGEVAK LSKELEDAKN EMASLSAVVV APSVSSSAAV PPAPPLPGDS GTVIPPPPPP PPLPGGVVPP SPPLPPGTCI PPPPPLPGGA CIPPPPQLPG SAAIPPPPPL PGVASIPPPP PLPGATAIPP PPPLPGATAI PPPPPLPGGT GIPPPPPPLP GSVGVPPPPP LPGGPGLPPP PPPFPGAPGI PPPPPGMGVP PPPPFGFGVP AAPVLPFGLT PKKVYKPEVQ LRRPNWSKFV AEDLSQDCFW TKVKEDRFEN NELFAKLTLA FSAQTKTSKA KKDQEGGEEK KSVQKKKVKE LKVLDSKTAQ NLSIFLGSFR MPYQEIKNVI LEVNEAVLTE SMIQNLIKQM PEPEQLKMLS ELKEEYDDLA ESEQFGVVMG TVPRLRPRLN AILFKLQFSE QVENIKPEIV SVTAACEELR KSENFSSLLE LTLLVGNYMN AGSRNAGAFG FNISFLCKLR DTKSADQKMT LLHFLAELCE NDHPEVLKFP DELAHVEKAS RVSAENLQKS LDQMKKQIAD VERDVQNFPA ATDEKDKFVE KMTSFVKDAQ EQYNKLRMMH SNMETLYKEL GDYFVFDPKK LSVEEFFMDL HNFRNMFLQA VKENQKRRET EEKMRRAKLA KEKAEKERLE KQQKREQLID MNAEGDETGV MDSLLEALQS GAAFRRKRGP RQVNRKAGCA VTSLLASELT KDDAMAPGPV KVPKKSEGVP TILEEAKELV GRAS
Genular Protein ID: 2720077653
Symbol: F6XC54_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16452087
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
PubMed ID: 16452087
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1220
- Mass: 135843
- Checksum: E7D0FFBE8252BDA2
- Sequence:
MADELERFTS MRIKKEKEKP NSAHRNSSAS YGDDPTAQSL QDISDEQVLV LFEQMLVDMN LNEEKQQPLR EKDIVIKREM VSQYLHTSKA GMNQKESSRS AMMYIQELRS GLRDMHLLSC LESLRVSLNN NPVSWVQTFG AEGLASLLDI LKRLHDEKEE TSGNYDSRNQ HEIIRCLKAF MNNKFGIKTM LETEEGILLL VRAMDPAVPN MMIDAAKLLS ALCILPQPED MNERVLEAMT ERAEMDEVER FQPLLDGLKS GTSIALKVGC LQLINALITP AEELDFRVHI RSELMRLGLH QVLQELREIE NEDMKVQLCV FDEQGDEDFF DLKGRLDDIR MEMDDFGEVF QIILNTVKDS KAEPHFLSIL QHLLLVRNDY EARPQYYKLI EECVSQIVLH KNGTDPDFKC RHLQIDIERL VDQMIDKTKV EKSEAKATEL EKKLDSELTA RHELQVEMKK MENDFEQKLQ DLQGEKDALD SEKQQITAQK QDLEAEVSKL TGEVAKLSKE LEDAKNEMAS LSAVVVAPSV SSSAAVPPAP PLPGDSGTVI PPPPPPPPLP GGVVPPSPPL PPGTCIPPPP PLPGGACIPP PPQLPGSAAI PPPPPLPGVA SIPPPPPLPG ATAIPPPPPL PGATAIPPPP PLPGGTGIPP PPPPLPGSVG VPPPPPLPGG PGLPPPPPPF PGAPGIPPPP PGMGVPPPPP FGFGVPAAPV LPFGLTPKKV YKPEVQLRRP NWSKFVAEDL SQDCFWTKVK EDRFENNELF AKLTLAFSAQ TKTSKAKKDQ EGGEEKKSVQ KKKVKELKVL DSKTAQNLSI FLGSFRMPYQ EIKNVILEVN EAVLTESMIQ NLIKQMPEPE QLKMLSELKE EYDDLAESEQ FGVVMGTVPR LRPRLNAILF KLQFSEQVEN IKPEIVSVTA ACEELRKSEN FSSLLELTLL VGNYMNAGSR NAGAFGFNIS FLCKLRDTKS ADQKMTLLHF LAELCENDHP EVLKFPDELA HVEKASRVSA ENLQKSLDQM KKQIADVERD VQNFPAATDE KDKFVEKMTS FVKDAQEQYN KLRMMHSNME TLYKELGDYF VFDPKKLSVE EFFMDLHNFR NMFLQAVKEN QKRRETEEKM RRAKLAKEKA EKERLEKQQK REQLIDMNAE GDETGVMDSL LEALQSGAAF RRKRGPRQVN RKAGCAVTSL LASELTKDDA MAPGPVKVPK KSEGVPTILE EAKELVGRAS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.