Details for: Dlx1

Gene ID: 13390

Symbol: Dlx1

Ensembl ID: ENSMUSG00000041911

Description: distal-less homeobox 1

Associated with

  • Cell differentiation
    (GO:0030154)
  • Cellular response to bmp stimulus
    (GO:0071773)
  • Cellular response to transforming growth factor beta stimulus
    (GO:0071560)
  • Cerebral cortex gabaergic interneuron differentiation
    (GO:0021892)
  • Cerebral cortex gabaergic interneuron fate commitment
    (GO:0021893)
  • Chromatin binding
    (GO:0003682)
  • Cytosol
    (GO:0005829)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Embryo development
    (GO:0009790)
  • Embryonic skeletal system development
    (GO:0048706)
  • Forebrain neuron differentiation
    (GO:0021879)
  • Gabaergic neuron differentiation
    (GO:0097154)
  • Hippocampus development
    (GO:0021766)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of bmp signaling pathway
    (GO:0030514)
  • Negative regulation of cellular response to transforming growth factor beta stimulus
    (GO:1903845)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Negative regulation of notch signaling pathway
    (GO:0045746)
  • Negative regulation of oligodendrocyte differentiation
    (GO:0048715)
  • Negative regulation of photoreceptor cell differentiation
    (GO:0046533)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuroblast differentiation
    (GO:0014016)
  • Neuron apoptotic process
    (GO:0051402)
  • Notch signaling pathway
    (GO:0007219)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Odontogenesis of dentin-containing tooth
    (GO:0042475)
  • Oligodendrocyte differentiation
    (GO:0048709)
  • Positive regulation of amacrine cell differentiation
    (GO:1902871)
  • Positive regulation of cell differentiation
    (GO:0045597)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Proximal/distal pattern formation
    (GO:0009954)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Subpallium development
    (GO:0021544)

Other Information

Genular Protein ID: 2234760920

Symbol: DLX1_MOUSE

Name: Homeobox protein DLX-1

UniProtKB Accession Codes:

Q64317

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 37 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 7 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 8812481

Title: Sequence, organization, and transcription of the Dlx-1 and Dlx-2 locus.

PubMed ID: 8812481

DOI: 10.1006/geno.1996.0387

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1676488

Title: A mouse gene related to Distal-less shows a restricted expression in the developing forebrain.

PubMed ID: 1676488

DOI: 10.1038/351748a0

PubMed ID: 21875655

Title: Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina.

PubMed ID: 21875655

DOI: 10.1016/j.neuroscience.2011.08.015

Sequence Information:

  • Length: 255
  • Mass: 27309
  • Checksum: 99B474F5D3FD8B6D
  • Sequence:
    • MTMTTMPESL NSPVSGKAVF MEFGPPNQQM SPSPMSHGHY SMHCLHSAGH SQPDGAYSSA 
SSFSRPLGYP YVNSVSSHAS SPYISSVQSY PGSASLAQSR LEDPGADSEK STVVEGGEVR 
FNGKGKKIRK PRTIYSSLQL QALNRRFQQT QYLALPERAE LAASLGLTQT QVKIWFQNKR 
SKFKKLMKQG GAALEGSALA NGRALSAGSP PVPPGWNPNS SSGKGSGSSA GSYVPSYTSW 
YPSAHQEAMQ QPQLM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.