COX6B1 | ENSG00000126267 | NCBI 1340

Details for: COX6B1

Gene ID: 1340

Symbol: COX6B1

Ensembl ID: ENSG00000126267

Description: cytochrome c oxidase subunit 6B1

Associated with

Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to chemical stress
(R-HSA-9711123)
Cytoprotection by hmox1
(R-HSA-9707564)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Metabolism
(R-HSA-1430728)
Respiratory electron transport
(R-HSA-611105)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-HSA-163200)
Rna polymerase ii transcription
(R-HSA-73857)
The citric acid (tca) cycle and respiratory electron transport
(R-HSA-1428517)
Tp53 regulates metabolic genes
(R-HSA-5628897)
Transcriptional regulation by tp53
(R-HSA-3700989)
Cellular respiration
(GO:0045333)
Cytochrome-c oxidase activity
(GO:0004129)
Mitochondrial electron transport, cytochrome c to oxygen
(GO:0006123)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial membrane
(GO:0031966)
Mitochondrial respiratory chain complex iv
(GO:0005751)
Mitochondrion
(GO:0005739)
Proton transmembrane transport
(GO:1902600)
Respiratory chain complex iv
(GO:0045277)
Substantia nigra development
(GO:0021762)

Other Information

Proteins

Cytochrome c oxidase subunit 6B1

Genular Protein ID: 3802753109

Symbol: CX6B1_HUMAN

Name: Cytochrome c oxidase subunit 6B1

UniProtKB Accession Codes:

P14854 B2R5C9 Q6IBL4

Database IDs:

Citations:

PubMed ID: 2537962

Title: Nucleotide sequence of cDNA encoding subunit VIb of human cytochrome c oxidase.

PubMed ID: 2537962

DOI: 10.1093/nar/17.4.1766

PubMed ID: 2172092

Title: Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues.

PubMed ID: 2172092

DOI: 10.1016/0378-1119(90)90237-l

PubMed ID: 1651883

Title: Human cytochrome c oxidase subunit VIb: characterization and mapping of a multigene family.

PubMed ID: 1651883

DOI: 10.1016/0378-1119(91)90082-m

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1647217

Title: Nucleotide sequence of the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking regions.

PubMed ID: 1647217

DOI: 10.1016/0167-4781(91)90027-j

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28844695

Title: Architecture of human mitochondrial respiratory megacomplex I2III2IV2.

PubMed ID: 28844695

DOI: 10.1016/j.cell.2017.07.050

PubMed ID: 30030519

Title: Structure of the intact 14-subunit human cytochrome c oxidase.

PubMed ID: 30030519

DOI: 10.1038/s41422-018-0071-1

PubMed ID: 18499082

Title: Severe infantile encephalomyopathy caused by a mutation in COX6B1, a nucleus-encoded subunit of cytochrome c oxidase.

PubMed ID: 18499082

DOI: 10.1016/j.ajhg.2008.05.002

PubMed ID: 24781756

Title: Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy.

PubMed ID: 24781756

DOI: 10.1038/ejhg.2014.85

Sequence Information:

Length: 86
Mass: 10192
Checksum: 15C8B056491FB248
Sequence:

MAEDMETKIK NYKTAPFDSR FPNQNQTRNC WQNYLDFHRC QKAMTAKGGD ISVCEWYQRV 
YQSLCPTSWV TDWDEQRAEG TFPGKI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: COX6B1

Associated with

Other Information

Nucleotide sequence of cDNA encoding subunit VIb of human cytochrome c oxidase. PubMed ID: 2537962

Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues. PubMed ID: 2172092

Human cytochrome c oxidase subunit VIb: characterization and mapping of a multigene family. PubMed ID: 1651883

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nucleotide sequence of the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking regions. PubMed ID: 1647217

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Architecture of human mitochondrial respiratory megacomplex I2III2IV2. PubMed ID: 28844695

Structure of the intact 14-subunit human cytochrome c oxidase. PubMed ID: 30030519

Severe infantile encephalomyopathy caused by a mutation in COX6B1, a nucleus-encoded subunit of cytochrome c oxidase. PubMed ID: 18499082

Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy. PubMed ID: 24781756