Details for: Dmc1

Gene ID: 13404

Symbol: Dmc1

Ensembl ID: ENSMUSG00000022429

Description: DNA meiotic recombinase 1

Associated with

Other Information

Genular Protein ID: 1903276037

Symbol: DMC1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q61880

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 9 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 30 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 MGI 2 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8581742

Title: Characterization of a mouse recA-like gene specifically expressed in testis.

PubMed ID: 8581742

DOI: 10.1093/dnares/2.3.147

PubMed ID: 8602360

Title: The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.

PubMed ID: 8602360

DOI: 10.1093/nar/24.3.470

PubMed ID: 15834424

Title: The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.

PubMed ID: 15834424

DOI: 10.1038/nsmb923

PubMed ID: 17639081

Title: Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing.

PubMed ID: 17639081

DOI: 10.1101/gad.1562907

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21307306

Title: Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1).

PubMed ID: 21307306

DOI: 10.1073/pnas.1016454108

PubMed ID: 22549958

Title: Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.

PubMed ID: 22549958

DOI: 10.1101/gad.187559.112

PubMed ID: 30760716

Title: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.

PubMed ID: 30760716

DOI: 10.1038/s41467-019-08676-2

PubMed ID: 30949703

Title: SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice.

PubMed ID: 30949703

DOI: 10.1093/nar/gkz226

PubMed ID: 30746471

Title: SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I.

PubMed ID: 30746471

DOI: 10.1126/sciadv.aau9780

PubMed ID: 32463460

Title: MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis.

PubMed ID: 32463460

DOI: 10.1093/nar/gkaa406

Sequence Information:

  • Length: 340
  • Mass: 37821
  • Checksum: 23EAB08D6E668637
  • Sequence:
    • MKEDQVVQEE SGFQDDEESL FQDIDLLQKH GINMADIKKL KSVGICTIKG IQMTTRRALC 
NVKGLSEAKV EKIKEAANKL IEPGFLTAFQ YSERRKMVFH ITTGSQEFDK LLGGGIESMA 
ITEAFGEFRT GKTQLSHTLC VTAQLPGTGG YSGGKIIFID TENTFRPDRL RDIADRFNVD 
HEAVLDNVLY ARAYTSEHQM ELLDYVAAKF HEEAGIFKLL IIDSIMALFR VDFSGRGELA 
ERQQKLAQML SRLQKISEEY NVAVFVTNQM TADPGATMTF QADPKKPIGG HILAHASTTR 
ISLRKGRGEL RIAKIYDSPE MPENEATFAI TAGGIGDAKE

Genular Protein ID: 2973735156

Symbol: Q8C610_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C610

Database IDs:

AGR 1 ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 2 GeneTree 1 InterPro 6 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 4 Pfam 2 Proteomes 2 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 285
  • Mass: 31665
  • Checksum: 98A2CA3C33F6947D
  • Sequence:
    • MKEDQVVQEE SGFQDDEESL FQDIDLLQKH GINMADIKKL KSVGICTIKG IQMTTRRALC 
NVKGLSEAKV EKIKEAANKL IEPGFLTAFQ YSERRKMVFH ITTGSQEFDK LLGGGIESMA 
ITEAFGEFRT GKTQLSHTLC GEHQMELLDY VAAKFHEEAG IFKLLIIDSI MALFRVDFSG 
RGELAERQQK LAQMLSRLQK ISEEYNVAVF VTNQMTADPG ATMTFQADPK KPIGGHILAH 
ASTTRISLRK GRGELRIAKI YDSPEMPENE ATFAITAGGI GDAKE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.