Genular: Defining Cellular Identity and Function

Details for: Dmp1

Gene ID: 13406

Symbol: Dmp1

Ensembl ID: ENSMUSG00000029307

Description: dentin matrix protein 1

Associated with

Ecm proteoglycans
(R-MMU-3000178)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Biomineral tissue development
(GO:0031214)
Cytoplasm
(GO:0005737)
Extracellular matrix
(GO:0031012)
Extracellular matrix binding
(GO:0050840)
Extracellular matrix organization
(GO:0030198)
Extracellular region
(GO:0005576)
Hsp70 protein binding
(GO:0030544)
Ion binding
(GO:0043167)
Nucleus
(GO:0005634)
Ossification
(GO:0001503)
Positive regulation of cell-substrate adhesion
(GO:0010811)
Regulation of enamel mineralization
(GO:0070173)

Other Information

Proteins

DMP1_MOUSE

Genular Protein ID: 3128530345

Symbol: DMP1_MOUSE

Name: N/A

UniProtKB Accession Codes:

O55188 Q3TZB6

Database IDs:

Citations:

PubMed ID: 9525343

Title: Identification of a novel isoform of mouse dentin matrix protein 1: spatial expression in mineralized tissues.

PubMed ID: 9525343

DOI: 10.1359/jbmr.1998.13.3.422

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 17033621

Title: Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

PubMed ID: 17033621

DOI: 10.1038/ng1905

PubMed ID: 24028588

Title: Msx1 regulates proliferation and differentiation of mouse dental mesenchymal cells in culture.

PubMed ID: 24028588

DOI: 10.1111/eos.12078

PubMed ID: 29148101

Title: Homeobox protein MSX-1 inhibits expression of bone morphogenetic protein 2, bone morphogenetic protein 4, and lymphoid enhancer-binding factor 1 via Wnt/beta-catenin signaling to prevent differentiation of dental mesenchymal cells during the late bell stage.

PubMed ID: 29148101

DOI: 10.1111/eos.12390

Sequence Information:

Length: 503
Mass: 53965
Checksum: A8FA932A126F8541
Sequence:

MKTVILLVFL WGLSCALPVA RYHNTESESS EERTGDLAGS PPPPTNSESS EESQASPEGQ 
ANSDHTDSSE SGEELGYDRG QYRPAGGLSK STGTGADKED DEDDSGDDTF GDEDNDLGPE 
EGQWGGPSKL DSDEDSTDTT QSSEDSTSQE NSAQDTPSDS KDHDSEDEAD SRPEAGDSTQ 
DSESEEQRVG GGSEGESSHG DGSEFDDEGM QSDDPESTRS DRGHARMSSA GIRSEESKGD 
HEPTSTQDSD DSQSVEFSSR KSFRRSHVSE EDYRGELTDS NSRETQSDST EDTASKEESR 
SESQEDTAES QSQEDSPEGQ DPSSESSEEA GEPSQESSSE SQEGVTSESR GDNPDNTSQA 
GDQEDSESSE EDSLNTFSSS ESQSTEEQAD SESNESLSLS EESQESAQDG DSSSQEGLQS 
QSASTESRSQ ESQSEQDSRS EEDSDSQDSS RSKEESNSTG SASSSEEDIR PKNMEADSRK 
LIVDAYHNKP IGDQDDNDCQ DGY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dmp1

Associated with

Other Information

Identification of a novel isoform of mouse dentin matrix protein 1: spatial expression in mineralized tissues. PubMed ID: 9525343

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. PubMed ID: 17033621