Details for: Tmc1
Associated with
Other Information
Genular Protein ID: 833102566
Symbol: TMC1_MOUSE
Name: Transmembrane channel-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11850618
Title: Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function.
PubMed ID: 11850618
DOI: 10.1038/ng842
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 12812529
Title: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
PubMed ID: 12812529
PubMed ID: 11850623
Title: Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.
PubMed ID: 11850623
DOI: 10.1038/ng848
PubMed ID: 25114259
Title: Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2.
PubMed ID: 25114259
PubMed ID: 28504928
Title: The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.
PubMed ID: 28504928
DOI: 10.7554/elife.24318
PubMed ID: 28534737
Title: Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).
PubMed ID: 28534737
DOI: 10.7554/elife.28474
PubMed ID: 28663585
Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
PubMed ID: 28663585
PubMed ID: 34089643
Title: CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
PubMed ID: 34089643
Sequence Information:
- Length: 757
- Mass: 87264
- Checksum: 9FB6CB73A7DD367D
- Sequence:
MLQIQVEEKE EDTEESSSEE EEDKLPRRES LRPKRKRTRD VINEDDPEPE PEDEETRKAR EKERRRRLRR GAEEEEEIDE EELERLKALL DENRQMIATV KCKPWKMEKK IEVLKEAKKF VSENEGALGK GKGKKWFAFK MMMAKKWAKF LRDFENFKAA CVPWENKIKA IESQFGSSVA SYFLFLRWMY GVNMVLFVLT FSLIMLPEYL WGLPYGSLPR KTVPRAEEAS AANFGVLYDF NGLAQYSVLF YGYYDNKRTI GWLNFRLPLS YFLVGIMCIG YSFLVVLKAM TKNIGDDGGG DDNTFNFSWK VFCSWDYLIG NPETADNKFN SITMNFKEAI IEERAAQVEE NIHLIRFLRF LANFFVFLTL GASGYLIFWA VKRSQEFAQQ DPDTLGWWEK NEMNMVMSLL GMFCPTLFDL FAELEDYHPL IALKWLLGRI FALLLGNLYV FILALMDEIN NKIEEEKLVK ANITLWEANM IKAYNESLSG LSGNTTGAPF FVHPADVPRG PCWETMVGQE FVRLTVSDVL TTYVTILIGD FLRACFVRFC NYCWCWDLEY GYPSYTEFDI SGNVLALIFN QGMIWMGSFF APSLPGINIL RLHTSMYFQC WAVMCCNVPE ARVFKASRSN NFYLGMLLLI LFLSTMPVLY MIVSLPPSFD CGPFSGKNRM FEVIGETLEH DFPSWMAKIL RQLSNPGLVI AVILVMVLTI YYLNATAKGQ KAANLDLKKK MKQQALENKM RNKKMAAARA AAAAGGQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.