Details for: Dnase1l3

Gene ID: 13421

Symbol: Dnase1l3

Ensembl ID: ENSMUSG00000025279

Description: deoxyribonuclease 1-like 3

Associated with

Other Information

Genular Protein ID: 3362539895

Symbol: DNSL3_MOUSE

Name: Deoxyribonuclease gamma

UniProtKB Accession Codes:

O55070 Q91X38

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EC 1 EMBL 4 Ensembl 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9714828

Title: Cloning and characterization of an actin-resistant DNase I-like endonuclease secreted by macrophages.

PubMed ID: 9714828

DOI: 10.1016/s0378-1119(98)00281-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10807908

Title: A role of the Ca2+/Mg2+-dependent endonuclease in apoptosis and its inhibition by poly(ADP-ribose) polymerase.

PubMed ID: 10807908

DOI: 10.1074/jbc.m001087200

PubMed ID: 12050166

Title: Involvement of DNase gamma in apoptosis associated with myogenic differentiation of C2C12 cells.

PubMed ID: 12050166

DOI: 10.1074/jbc.m204038200

PubMed ID: 12095301

Title: Deoxyribonuclease I-like III is an inducible macrophage barrier to liposomal transfection.

PubMed ID: 12095301

DOI: 10.1006/mthe.2002.0625

PubMed ID: 15167901

Title: Differential DNases are selectively used in neuronal apoptosis depending on the differentiation state.

PubMed ID: 15167901

DOI: 10.1038/sj.cdd.4401454

PubMed ID: 15796714

Title: Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3).

PubMed ID: 15796714

DOI: 10.1042/bj20042124

PubMed ID: 17218958

Title: Stage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.

PubMed ID: 17218958

DOI: 10.1038/sj.cdd.4402086

PubMed ID: 19154352

Title: Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).

PubMed ID: 19154352

DOI: 10.1111/j.1742-4658.2008.06849.x

PubMed ID: 24312463

Title: DNase gamma is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.

PubMed ID: 24312463

DOI: 10.1371/journal.pone.0080223

PubMed ID: 27293190

Title: Digestion of chromatin in apoptotic cell microparticles prevents autoimmunity.

PubMed ID: 27293190

DOI: 10.1016/j.cell.2016.05.034

PubMed ID: 29191910

Title: Host DNases prevent vascular occlusion by neutrophil extracellular traps.

PubMed ID: 29191910

DOI: 10.1126/science.aam8897

PubMed ID: 12974753

Title: Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.

PubMed ID: 12974753

DOI: 10.1046/j.1365-2249.2003.02267.x

Sequence Information:

  • Length: 310
  • Mass: 35760
  • Checksum: BE483821E045E374
  • Sequence:
    • MSLHPASPRL ASLLLFILAL HDTLALRLCS FNVRSFGASK KENHEAMDII VKIIKRCDLI 
LLMEIKDSSN NICPMLMEKL NGNSRRSTTY NYVISSRLGR NTYKEQYAFV YKEKLVSVKT 
KYHYHDYQDG DTDVFSREPF VVWFHSPFTA VKDFVIVPLH TTPETSVKEI DELVDVYTDV 
RSQWKTENFI FMGDFNAGCS YVPKKAWQNI RLRTDPKFVW LIGDQEDTTV KKSTSCAYDR 
IVLCGQEIVN SVVPRSSGVF DFQKAYDLSE EEALDVSDHF PVEFKLQSSR AFTNNRKSVS 
LKKRKKGNRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.