Details for: Dnmt1
Associated with
Other Information
Genular Protein ID: 3146007068
Symbol: DNMT1_MOUSE
Name: DNA (cytosine-5)-methyltransferase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3210246
Title: Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases.
PubMed ID: 3210246
PubMed ID: 8940105
Title: New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase.
PubMed ID: 8940105
PubMed ID: 11063128
Title: Expression of an alternative Dnmt1 isoform during muscle differentiation.
PubMed ID: 11063128
PubMed ID: 10715201
Title: Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure.
PubMed ID: 10715201
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9449671
Title: Sex-specific exons control DNA methyltransferase in mammalian germ cells.
PubMed ID: 9449671
PubMed ID: 9830015
Title: A short DNA methyltransferase isoform restores methylation in vivo.
PubMed ID: 9830015
PubMed ID: 8917520
Title: Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene.
PubMed ID: 8917520
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 1628623
Title: Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain.
PubMed ID: 1628623
PubMed ID: 9211941
Title: Peptide mapping of the murine DNA methyltransferase reveals a major phosphorylation site and the start of translation.
PubMed ID: 9211941
PubMed ID: 10615135
Title: DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
PubMed ID: 10615135
DOI: 10.1038/71750
PubMed ID: 10888872
Title: DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
PubMed ID: 10888872
DOI: 10.1038/77023
PubMed ID: 11290321
Title: Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene.
PubMed ID: 11290321
PubMed ID: 11399088
Title: The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.
PubMed ID: 11399088
PubMed ID: 15550930
Title: Replication-independent chromatin loading of Dnmt1 during G2 and M phases.
PubMed ID: 15550930
PubMed ID: 16085498
Title: The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.
PubMed ID: 16085498
PubMed ID: 16357870
Title: The Polycomb group protein EZH2 directly controls DNA methylation.
PubMed ID: 16357870
DOI: 10.1038/nature04431
PubMed ID: 17965600
Title: Phosphorylation of serine-515 activates the mammalian maintenance methyltransferase Dnmt1.
PubMed ID: 17965600
DOI: 10.4161/epi.2.3.4768
PubMed ID: 17576694
Title: Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.
PubMed ID: 17576694
DOI: 10.1093/nar/gkm432
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21268065
Title: Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1.
PubMed ID: 21268065
DOI: 10.1002/jcb.22998
PubMed ID: 20192920
Title: The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.
PubMed ID: 20192920
DOI: 10.1042/bj20091856
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
PubMed ID: 28842251
Title: Sirt7 stabilizes rDNA heterochromatin through recruitment of DNMT1 and Sirt1.
PubMed ID: 28842251
PubMed ID: 21163962
Title: Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
PubMed ID: 21163962
Sequence Information:
- Length: 1620
- Mass: 183189
- Checksum: 4F9A98CEAF09F037
- Sequence:
MPARTAPARV PALASPAGSL PDHVRRRLKD LERDGLTEKE CVREKLNLLH EFLQTEIKSQ LCDLETKLHK EELSEEGYLA KVKSLLNKDL SLENGTHTLT QKANGCPANG SRPTWRAEMA DSNRSPRSRP KPRGPRRSKS DSDTLSVETS PSSVATRRTT RQTTITAHFT KGPTKRKPKE ESEEGNSAES AAEERDQDKK RRVVDTESGA AAAVEKLEEV TAGTQLGPEE PCEQEDDNRS LRRHTRELSL RRKSKEDPDR EARPETHLDE DEDGKKDKRS SRPRSQPRDP AAKRRPKEAE PEQVAPETPE DRDEDEREEK RRKTTRKKLE SHTVPVQSRS ERKAAQSKSV IPKINSPKCP ECGQHLDDPN LKYQQHPEDA VDEPQMLTSE KLSIYDSTST WFDTYEDSPM HRFTSFSVYC SRGHLCPVDT GLIEKNVELY FSGCAKAIHD ENPSMEGGIN GKNLGPINQW WLSGFDGGEK VLIGFSTAFA EYILMEPSKE YEPIFGLMQE KIYISKIVVE FLQNNPDAVY EDLINKIETT VPPSTINVNR FTEDSLLRHA QFVVSQVESY DEAKDDDETP IFLSPCMRAL IHLAGVSLGQ RRATRRVMGA TKEKDKAPTK ATTTKLVYQI FDTFFSEQIE KYDKEDKENA MKRRRCGVCE VCQQPECGKC KACKDMVKFG GTGRSKQACL KRRCPNLAVK EADDDEEADD DVSEMPSPKK LHQGKKKKQN KDRISWLGQP MKIEENRTYY QKVSIDEEML EVGDCVSVIP DDSSKPLYLA RVTALWEDKN GQMMFHAHWF CAGTDTVLGA TSDPLELFLV GECENMQLSY IHSKVKVIYK APSENWAMEG GTDPETTLPG AEDGKTYFFQ LWYNQEYARF ESPPKTQPTE DNKHKFCLSC IRLAELRQKE MPKVLEQIEE VDGRVYCSSI TKNGVVYRLG DSVYLPPEAF TFNIKVASPV KRPKKDPVNE TLYPEHYRKY SDYIKGSNLD APEPYRIGRI KEIHCGKKKG KVNEADIKLR LYKFYRPENT HRSYNGSYHT DINMLYWSDE EAVVNFSDVQ GRCTVEYGED LLESIQDYSQ GGPDRFYFLE AYNSKTKNFE DPPNHARSPG NKGKGKGKGK GKGKHQVSEP KEPEAAIKLP KLRTLDVFSG CGGLSEGFHQ AGISETLWAI EMWDPAAQAF RLNNPGTTVF TEDCNVLLKL VMAGEVTNSL GQRLPQKGDV EMLCGGPPCQ GFSGMNRFNS RTYSKFKNSL VVSFLSYCDY YRPRFFLLEN VRNFVSYRRS MVLKLTLRCL VRMGYQCTFG VLQAGQYGVA QTRRRAIILA AAPGEKLPLF PEPLHVFAPR ACQLSVVVDD KKFVSNITRL SSGPFRTITV RDTMSDLPEI QNGASNSEIP YNGEPLSWFQ RQLRGSHYQP ILRDHICKDM SPLVAARMRH IPLFPGSDWR DLPNIQVRLG DGVIAHKLQY TFHDVKNGYS STGALRGVCS CAEGKACDPE SRQFSTLIPW CLPHTGNRHN HWAGLYGRLE WDGFFSTTVT NPEPMGKQGR VLHPEQHRVV SVRECARSQG FPDSYRFFGN ILDRHRQVGN AVPPPLAKAI GLEIKLCLLS SARESASAAV KAKEEAATKD
Genular Protein ID: 2059966421
Symbol: J3QNW0_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
Sequence Information:
- Length: 1501
- Mass: 169957
- Checksum: 3325C8F8EC45A767
- Sequence:
MADSNRSPRS RPKPRGPRRS KSDSDTLFET SPSSVATRRT TRQTTITAHF TKGPTKRKPK EESEEGNSAE SAAEERDQDK KRRVVDTESG AAAAVEKLEE VTAGTQLGPE EPCEQEDDNR SLRRHTRELS LRRKSKEDPD REARPETHLD EDEDGKKDKR SSRPRSQPRD PAAKRRPKEA EPEQVAPETP EDRDEDEREE KRRKTTRKKL ESHTVPVQSR SERKAAQSKS VIPKINSPKC PECGQHLDDP NLKYQQHPED AVDEPQMLTS EKLSIYDSTS TWFDTYEDSP MHRFTSFSVY CSRGHLCPVD TGLIEKNVEL YFSGCAKAIH DENPSMEGGI NGKNLGPINQ WWLSGFDGGE KVLIGFSTAF AEYILMEPSK EYEPIFGLMQ EKIYISKIVV EFLQNNPDAV YEDLINKIET TVPPSTINVN RFTEDSLLRH AQFVVSQVES YDEAKDDDET PIFLSPCMRA LIHLAGVSLG QRRATRRVMG ATKEKDKAPT KATTTKLVYQ IFDTFFSEQI EKYDKEDKEN AMKRRRCGVC EVCQQPECGK CKACKDMVKF GGTGRSKQAC LKRRCPNLAV KEADDDEEAD DDVSEMPSPK KLHQGKKKKQ NKDRISWLGQ PMKIEENRTY YQKVSIDEEM LEVGDCVSVI PDDSSKPLYL ARVTALWEDK NGQMMFHAHW FCAGTDTVLG ATSDPLELFL VGECENMQLS YIHSKVKVIY KAPSENWAME GGTDPETTLP GAEDGKTYFF QLWYNQEYAR FESPPKTQPT EDNKHKFCLS CIRLAELRQK EMPKVLEQIE EVDGRVYCSS ITKNGVVYRL GDSVYLPPEA FTFNIKVASP VKRPKKDPVN ETLYPEHYRK YSDYIKGSNL DAPEPYRIGR IKEIHCGKKK GKVNEADIKL RLYKFYRPEN THRSYNGSYH TDINMLYWSD EEAVVNFSDV QGRCTVEYGE DLLESIQDYS QGGPDRFYFL EAYNSKTKNF EDPPNHARSP GNKGKGKGKG KGKGKHQVSE PKEPEAAIKL PKLRTLDVFS GCGGLSEGFH QAGISETLWA IEMWDPAAQA FRLNNPGTTV FTEDCNVLLK LVMAGEVTNS LGQRLPQKGD VEMLCGGPPC QGFSGMNRFN SRTYSKFKNS LVVSFLSYCD YYRPRFFLLE NVRNFVSYRR SMVLKLTLRC LVRMGYQCTF GVLQAGQYGV AQTRRRAIIL AAAPGEKLPL FPEPLHVFAP RACQLSVVVD DKKFVSNITR LSSGPFRTIT VRDTMSDLPE IQNGASNSEI PYNGEPLSWF QRQLRGSHYQ PILRDHICKD MSPLVAARMR HIPLFPGSDW RDLPNIQVRL GDGVIAHKLQ YTFHDVKNGY SSTGALRGVC SCAEGKACDP ESRQFSTLIP WCLPHTGNRH NHWAGLYGRL EWDGFFSTTV TNPEPMGKQG RVLHPEQHRV VSVRECARSQ GFPDSYRFFG NILDRHRQVG NAVPPPLAKA IGLEIKLCLL SSARESASAA VKAKEEAATK D
Genular Protein ID: 1896419353
Symbol: Q3UWN4_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
Sequence Information:
- Length: 221
- Mass: 25286
- Checksum: E7C52786EB59E3C1
- Sequence:
MADSNRSPRS RPKPRGPRRS KSDSDTLFET SPSSVATRRT TRQTTITAHF TKGPTKRKPK EESEEGNSAE SAAEERDQDK KRRVVDTESG AAAAVEKLEE VTAGTQLGPE EPCEQEDDNR SLRRHTRELS LRRKSKEDPD REARPETHLD EDEDGKKDKR SSRPRSQPRD PAAKRRPKEA EPEQVAPETP EDRDEDEREE KRRKTTRKKL ESHTVPVQSR S
Genular Protein ID: 3925200289
Symbol: Q7TSJ0_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1627
- Mass: 184015
- Checksum: F23DC80D5FA9C5AE
- Sequence:
MPARTAPARV PALASPAGSL PDHVRRRLKD LERDGLTEKE CVREKLNLLH EFLQTEIKSQ LCDLETKLHK EELSEEGYLA KVKSLLNKDL SLENGTHTLT QKANGCPANG SRPTWRAEMA DSNRSPRSRP KPRGPRRSKS DSDTLCKDTR HTAVETSPSS VATRRTTRQT TITAHFTKGP TKRKPKEESE EGNSAESAAE ERDQDKKRRV VDTESGAAAA VEKLEEVTAG TQLGPEEPCE QEDDNRSLRR HTRELSLRRK SKEDPDREAR PETHLDEDED GKKDKRSSRP RSQPRDPAAK RRPKEAEPEQ VAPETPEDRD EDEREEKRRK TTRKKLESHT VPVQSRSERK AAQSKSVIPK INSPKCPECG QHLDDPNLKY QQHPEDAVDE PQMLTSEKLS IYDSTSTWFD TYEDSPMHRF TSFSVYCSRG HLCPVDTGLI EKNVELYFSG CAKAIHDENP SMEGGINGKN LGPINQWWLS GFDGGEKVLI GFSTAFAEYI LMEPSKEYEP IFGLMQEKIY ISKIVVEFLQ NNPDAVYEDL INKIETTVPP STINVNRFTE DSLLRHAQFV VSQVESYDEA KDDDETPIFL SPCMRALIHL AGVSLGQRRA TRRVMGATKE KDKAPTKATT TKLVYQIFDT FFSEQIEKYD KEDKENAMKR RRCGVCEVCQ QPECGKCKAC KDMVKFGGTG RSKQACLKRR CPNLAVKEAD DDEEADDDVS EMPSPKKLHQ GKKKKQNKDR ISWLGQPMKI EENRTYYQKV SIDEEMLEVG DCVSVIPDDS SKPLYLARVT ALWEDKNGQM MFHAHWFCAG TDTVLGATSD PLELFLVGEC ENMQLSYIHS KVKVIYKAPS ENWAMEGGTD PETTLPGAED GKTYFFQLWY NQEYARFESP PKTQPTEDNK HKFCLSCIRL AELRQKEMPK VLEQIEEVDG RVYCSSITKN GVVYRLGDSV YLPPEAFTFN IKVASPVKRP KKDPVNETLY PEHYRKYSDY IKGSNLDAPE PYRIGRIKEI HCGKKKGKVN EADIKLRLYK FYRPENTHRS YNGSYHTDIN MLYWSDEEAV VNFSDVQGRC TVEYGEDLLE SIQDYSQGGP DRFYFLEAYN SKTKNFEDPP NHARSPGNKG KGKGKGKGKG KHQVSEPKEP EAAIKLPKLR TLDVFSGCGG LSEGFHQAGI SETLWAIEMW DPAAQAFRLN NPGTTVFTED CNVLLKLVMA GEVTNSLGQR LPQKGDVEML CGGPPCQGFS GMNRFNSRTY SKFKNSLVVS FLSYCDYYRP RFFLLENVRN FVSYRRSMVL KLTLRCLVRM GYQCTFGVLQ AGQYGVAQTR RRAIILAAAP GEKLPLFPEP LHVFAPRACQ LSVVVDDKKF VSNITRLSSG PFRTITVRDT MSDLPEIQNG ASNSEIPYNG EPLSWFQRQL RGSHYQPILR DHICKDMSPL VAARMRHIPL FPGSDWRDLP NIQVRLGDGV IAHKLQYTFH DVKNGYSSTG ALRGVCSCAE GKACDPESRQ FSTLIPWCLP HTGNRHNHWA GLYGRLEWDG FFSTTVTNPE PMGKQGRVLH PEQHRVVSVR ECARSQGFPD SYRFFGNILD RHRQVGNAVP PPLAKAIGLE IKLCLLSSAR ESASAAVKAK EEAATKD
Genular Protein ID: 1783016596
Symbol: Q3UHZ3_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
Sequence Information:
- Length: 1619
- Mass: 183308
- Checksum: D49850074F76718F
- Sequence:
MPARTAPARV PALASPAGSL PDHVRRRLKD LERDGLTEKE CVREKLNLLH EFLQTEIKSQ LCDLETKLHK EELSEEGYLA KVKSLLNKDL SLENGTHTLT QKANGCPANG SRPTWRAEMA DSNRSPRSRR KPRGPRRSKS DSDTLFETSP SSVATRRTTR QTTITAHFTK GPTKRKPKEE SEEGNSAESA AEERDQDKKR RVVDTESGAA AAVEKLEEVT AGTQLGPEEP CEQEDDNRSL RRHTRELSLR RKSKEDPDRE ARPETHLDED EDGKKDKRSS RPRSQPRDPA AKRRPKEAEP EQVAPETPED RDEDEREEKR RKTTRKKLES HTVPVQSRSE RKAAQSKSVI PKINSPKCPE CGQHLDDPNL KYQQHPEDAV DEPQMLTSEK LSIYDSTSTW FDTYEDSPMH RFTSFSVYCS RGHLCPVDTG LIEKNVELYF SGCAKAIHDE NPSMEGGING KNLGPINQWW LSGFDGGEKV LIGFSTAFAE YILMEPSKEY EPIFGLMQEK IYISKIVVEF LQNNPDAVYE DLINKIETTV PPSTINVNRF TEDSLLRHAQ FVVSQVESYD EAKDDDETPI FLSPCMRALI HLAGVSLGQR RATRRVMGAT KEKDKAPTKA TTTKLVYQIF DTFFSEQIEK YDKEDKENAM KRRRCGVCEV CQQPECGKCK ACKDMVKFGG TGRSKQACLK RRCPNLAVKE ADDDEEADDD VSEMPSPKKL HQGKKKKQNK DRISWLGQPM KIEENRTYYQ KVSIDEEMLE VGDCVSVIPD DSSKPLYLAR VTALWEDKNG QMMFHAHWFC AGTDTVLRAT SDPLELFLVG ECENMQLSYI HSKVKVIYKA PSENWAMEGG TDPETTLPGA EDGKTYFFQL WYNQEYARFE SPPKTQPTED NKHKFCLSCI RLAELRQKEM PKVLEQIEEV DGRVYCSSIT KNGVVYRLGD SVYLPPEAFT FNIKVASPVK RPKKDPVNET LYPEHYRKYS DYIKGSNLDA PEPYRIGRIK EIHCGKKKGK VNEADIKLRL YKFYRPENTH RSYNGSYHTD INMLYWSDEE AVVNFSDVQG RCTVEYGEDL LESIQDYSQG GPDRFYFLEA YNSKTKNFED PPNHARSPGN KGKGKGKGKG KGKHQVSEPK EPEAAIKLPK LRTLDVFSGC GGLSEGFHQA GISETLWAIE MWDPAAQAFR LNNPGTTVFT EDCNVLLKLV MAGEVTNSLG QRLPQKGDVE MLCGGPPCQG FSGMNRFNSR TYSKFKNSLV VSFLSYCDYY RPRFFLLENV RNFVSYRRSM VLKLTLRCLV RMGYQCTFGV LQAGQYGVAQ TRRRAIILAA APGEKLPLFP EPLHVFAPRA CQLSVVVDDK KFVSNITRLS SGPFRTITVR DTMSDLPEIQ NGASNSEIPY NGEPLSWFQR QLRGSHYQPI LRDHICKDMS PLVAARMRHI PLFPGSDWRD LPNIQVRLGD GVIAHKLQYT FHDVKNGYSS TGALRGVCSC AEGKACDPES RQFSTLIPWC LPHTGNRHNH WAGLYGRLEW DGFFSTTVTN PEPMGKQGRV LHPEQHRVVS VRECARSQGF PDSYRFFGNI LDRHRQVGNA VPPPLAKAIG LEIKLCLLSS ARESASAAVK AKEEAATKD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.