Details for: Doc2b

Gene ID: 13447

Symbol: Doc2b

Ensembl ID: ENSMUSG00000020848

Description: double C2, beta

Associated with

Other Information

Genular Protein ID: 2747968926

Symbol: DOC2B_MOUSE

Name: Double C2-like domain-containing protein beta

UniProtKB Accession Codes:

P70169 Q5SS41 Q6NXK3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChEBI 13 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8902635

Title: Calcium-dependent phospholipid binding to the C2A domain of a ubiquitous form of double C2 protein (Doc2 beta).

PubMed ID: 8902635

DOI: 10.1093/oxfordjournals.jbchem.a021464

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17548353

Title: Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

PubMed ID: 17548353

DOI: 10.1074/jbc.m701661200

PubMed ID: 18596155

Title: DOC2B acts as a calcium switch and enhances vesicle fusion.

PubMed ID: 18596155

DOI: 10.1523/jneurosci.0538-08.2008

PubMed ID: 19410553

Title: DOC2b is a SNARE regulator of glucose-stimulated delayed insulin secretion.

PubMed ID: 19410553

DOI: 10.1016/j.bbrc.2009.04.133

PubMed ID: 19033398

Title: DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.

PubMed ID: 19033398

DOI: 10.2337/db08-0303

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20150444

Title: Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.

PubMed ID: 20150444

DOI: 10.1126/science.1183765

Sequence Information:

  • Length: 412
  • Mass: 45853
  • Checksum: 4E94480BEDE91722
  • Sequence:
    • MTLRRRGEKA TISIQEHMAI DVCPGPIRPI KQISDYFPRF PRGLPPTAAP RAPAPPDAPA 
RSPAASASPR SPSDGARDDD EDVDQLFGAY GASPGPSPGP SPARPPAKPP EDEPDVDGYE 
SDDCTALGTL DFSLLYDQEN NALHCTISKA KGLKPMDHNG LADPYVKLHL LPGASKANKL 
RTKTLRNTLN PSWNETLTYY GITDEDMVRK TLRISVCDED KFRHNEFIGE TRVPLKKLKP 
NHTKTFSICL EKQLPVDKAE DKSLEERGRI LISLKYSSQK QGLLVGIVRC AHLAAMDANG 
YSDPYVKTYL KPDVDKKSKH KTAVKKKTLN PEFNEEFCYE IKHGDLAKKT LEVTVWDYDI 
GKSNDFIGGV VLGINAKGER LKHWFDCLKN KDKRIERWHT LTNELPGAVL SD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.