Genular: Defining Cellular Identity and Function

Details for: Drd1

Gene ID: 13488

Symbol: Drd1

Ensembl ID: ENSMUSG00000021478

Description: dopamine receptor D1

Associated with

Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Dopamine receptors
(R-MMU-390651)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Signaling by gpcr
(R-MMU-372790)
Activation of adenylate cyclase activity
(GO:0007190)
Adenylate cyclase-activating dopamine receptor signaling pathway
(GO:0007191)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adult walking behavior
(GO:0007628)
Angiotensin receptor binding
(GO:0031701)
Arrestin family protein binding
(GO:1990763)
Associative learning
(GO:0008306)
Astrocyte development
(GO:0014002)
Atpase binding
(GO:0051117)
Behavioral fear response
(GO:0001662)
Calcium-mediated signaling
(GO:0019722)
Cell migration
(GO:0016477)
Cerebral cortex gabaergic interneuron migration
(GO:0021853)
Conditioned taste aversion
(GO:0001661)
D3 dopamine receptor binding
(GO:0031750)
Dentate gyrus development
(GO:0021542)
Dopamine binding
(GO:0035240)
Dopamine neurotransmitter receptor activity
(GO:0004952)
Dopamine neurotransmitter receptor activity, coupled via gs
(GO:0001588)
Dopamine receptor signaling pathway
(GO:0007212)
Dopamine transport
(GO:0015872)
Eating behavior
(GO:0042755)
Feeding behavior
(GO:0007631)
G-protein alpha-subunit binding
(GO:0001965)
Glucose import
(GO:0046323)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
Grooming behavior
(GO:0007625)
Habituation
(GO:0046959)
Heterocyclic compound binding
(GO:1901363)
Heterotrimeric g-protein binding
(GO:0032795)
Hippocampus development
(GO:0021766)
Intracellular protein transport
(GO:0006886)
Learning
(GO:0007612)
Locomotory behavior
(GO:0007626)
Maternal behavior
(GO:0042711)
Mating behavior
(GO:0007617)
Memory
(GO:0007613)
Muscle contraction
(GO:0006936)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of circadian sleep/wake cycle, sleep
(GO:0042321)
Neuronal action potential
(GO:0019228)
Neuron migration
(GO:0001764)
Operant conditioning
(GO:0035106)
Peristalsis
(GO:0030432)
Positive regulation of membrane potential
(GO:0045838)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Protein phosphatase binding
(GO:0019903)
Protein phosphorylation
(GO:0006468)
Regulation of dopamine metabolic process
(GO:0042053)
Regulation of monoatomic ion transport
(GO:0043269)
Regulation of protein phosphorylation
(GO:0001932)
Regulation of vasoconstriction
(GO:0019229)
Response to amphetamine
(GO:0001975)
Response to cocaine
(GO:0042220)
Response to xenobiotic stimulus
(GO:0009410)
Sensitization
(GO:0046960)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Social behavior
(GO:0035176)
Startle response
(GO:0001964)
Striatum development
(GO:0021756)
Synaptic transmission, dopaminergic
(GO:0001963)
Synaptic transmission, glutamatergic
(GO:0035249)
Temperature homeostasis
(GO:0001659)
Transmission of nerve impulse
(GO:0019226)
Vasodilation
(GO:0042311)
Visual learning
(GO:0008542)

Other Information

Proteins

D(1A) dopamine receptor

Genular Protein ID: 21959525

Symbol: DRD1_MOUSE

Name: D(1A) dopamine receptor

UniProtKB Accession Codes:

Q61616 B2RPW8 Q8C8P8

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8288218

Title: Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors.

PubMed ID: 8288218

DOI: 10.1006/geno.1993.1452

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25865831

Title: Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus.

PubMed ID: 25865831

DOI: 10.1111/jnc.13119

Sequence Information:

Length: 446
Mass: 49612
Checksum: 509BA66F9DF82A74
Sequence:

MAPNTSTMDE TGLPVERDFS FRILTACFLS LLILSTLLGN TLVCAAVIRF RHLRSKVTNF 
FVISLAVSDL LVAVLVMPWK AVAEIAGFWP FGSFCNIWVA FDIMCSTASI LNLCVISVDR 
YWAISSPFQY ERKMTPKAAF ILISVAWTLS VLISFIPVQL SWHKAKPTWP LDGNFTSLED 
AEDDNCDTRL SRTYAISSSL ISFYIPVAIM IVTYTSIYRI AQKQIRRISA LERAAVHAKN 
CQTTTGNGNP VECSQSESSF KMSFKRETKV LKTLSVIMGV FVCCWLPFFI SNCMVPFCGS 
EETQPFCIDS ITFDVFVWFG WANSSLNPII YAFNADFQKA FSTLLGCYRL CPTTNNAIET 
VSINNNGAVM FSSHHEPRGS ISKDCNLVYL IPHAVGSSED LKREEAGGIP KPLEKLSPAL 
SVILDYDTDV SLEKIQPVTH SGQHST

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Drd1

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. PubMed ID: 8288218