Genular: Defining Cellular Identity and Function

Details for: Drd2

Gene ID: 13489

Symbol: Drd2

Ensembl ID: ENSMUSG00000032259

Description: dopamine receptor D2

Associated with

Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Dopamine receptors
(R-MMU-390651)
Gpcr ligand binding
(R-MMU-500792)
Signaling by gpcr
(R-MMU-372790)
Adenohypophysis development
(GO:0021984)
Adenylate cyclase-inhibiting dopamine receptor signaling pathway
(GO:0007195)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Adult behavior
(GO:0030534)
Adult walking behavior
(GO:0007628)
Associative learning
(GO:0008306)
Auditory behavior
(GO:0031223)
Autophagy
(GO:0006914)
Axonogenesis
(GO:0007409)
Cell migration
(GO:0016477)
Cell population proliferation
(GO:0008283)
Cerebral cortex gabaergic interneuron migration
(GO:0021853)
Circadian regulation of gene expression
(GO:0032922)
Dopamine binding
(GO:0035240)
Dopamine metabolic process
(GO:0042417)
Dopamine neurotransmitter receptor activity
(GO:0004952)
Dopamine neurotransmitter receptor activity, coupled via gi/go
(GO:0001591)
Dopamine receptor signaling pathway
(GO:0007212)
Drinking behavior
(GO:0042756)
Feeding behavior
(GO:0007631)
Forebrain development
(GO:0030900)
G-protein alpha-subunit binding
(GO:0001965)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor internalization
(GO:0002031)
G protein-coupled receptor signaling pathway
(GO:0007186)
Grooming behavior
(GO:0007625)
Heterocyclic compound binding
(GO:1901363)
Heterotrimeric g-protein binding
(GO:0032795)
Identical protein binding
(GO:0042802)
Intracellular signal transduction
(GO:0035556)
Ionotropic glutamate receptor binding
(GO:0035255)
Locomotory behavior
(GO:0007626)
Long-term memory
(GO:0007616)
Negative regulation of adenylate cyclase activity
(GO:0007194)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of circadian sleep/wake cycle, sleep
(GO:0042321)
Negative regulation of dopamine secretion
(GO:0033602)
Negative regulation of protein phosphorylation
(GO:0001933)
Nervous system process involved in regulation of systemic arterial blood pressure
(GO:0001976)
Neuroblast proliferation
(GO:0007405)
Neuron-neuron synaptic transmission
(GO:0007270)
Neuron migration
(GO:0001764)
Organic cyclic compound binding
(GO:0097159)
Peristalsis
(GO:0030432)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Pigmentation
(GO:0043473)
Positive regulation of cytokinesis
(GO:0032467)
Positive regulation of multicellular organism growth
(GO:0040018)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of receptor internalization
(GO:0002092)
Positive regulation of renal sodium excretion
(GO:0035815)
Positive regulation of urine volume
(GO:0035810)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization
(GO:0008104)
Regulation of dopamine secretion
(GO:0014059)
Regulation of heart rate
(GO:0002027)
Regulation of mapk cascade
(GO:0043408)
Regulation of potassium ion transport
(GO:0043266)
Regulation of sodium ion transport
(GO:0002028)
Regulation of synaptic transmission, gabaergic
(GO:0032228)
Response to amphetamine
(GO:0001975)
Response to cocaine
(GO:0042220)
Response to histamine
(GO:0034776)
Response to hypoxia
(GO:0001666)
Response to light stimulus
(GO:0009416)
Response to morphine
(GO:0043278)
Response to xenobiotic stimulus
(GO:0009410)
Sensory perception of smell
(GO:0007608)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Startle response
(GO:0001964)
Temperature homeostasis
(GO:0001659)
Visual learning
(GO:0008542)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

D(2) dopamine receptor

Genular Protein ID: 2706221568

Symbol: DRD2_MOUSE

Name: D(2) dopamine receptor

UniProtKB Accession Codes:

P61168 P13953 Q0VGH9

Database IDs:

Citations:

PubMed ID: 1991517

Title: Differential expression of the mouse D2 dopamine receptor isoforms.

PubMed ID: 1991517

DOI: 10.1016/0014-5793(91)80125-m

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21233214

Title: Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.

PubMed ID: 21233214

DOI: 10.1074/jbc.m110.153262

PubMed ID: 25865831

Title: Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus.

PubMed ID: 25865831

DOI: 10.1111/jnc.13119

PubMed ID: 30936473

Title: An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.

PubMed ID: 30936473

DOI: 10.1038/s41556-019-0301-x

Sequence Information:

Length: 444
Mass: 50930
Checksum: 2EC8460CA11FC7F0
Sequence:

MDPLNLSWYD DDLERQNWSR PFNGSEGKPD RPHYNYYAML LTLLIFIIVF GNVLVCMAVS 
REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF VTLDVMMCTA 
SILNLCAISI DRYTAVAMPM LYNTRYSSKR RVTVMIAIVW VLSFTISCPL LFGLNNTDQN 
ECIIANPAFV VYSSIVSFYV PFIVTLLVYI KIYIVLRKRR KRVNTKRSSR AFRANLKTPL 
KGNCTHPEDM KLCTVIMKSN GSFPVNRRRM DAARRAQELE MEMLSSTSPP ERTRYSPIPP 
SHHQLTLPDP SHHGLHSNPD SPAKPEKNGH AKIVNPRIAK FFEIQTMPNG KTRTSLKTMS 
RRKLSQQKEK KATQMLAIVL GVFIICWLPF FITHILNIHC DCNIPPVLYS AFTWLGYVNS 
AVNPIIYTTF NIEFRKAFMK ILHC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Drd2

Associated with

Other Information

Differential expression of the mouse D2 dopamine receptor isoforms. PubMed ID: 1991517

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. PubMed ID: 21233214