Details for: ADORA2A

Gene ID: 135

Symbol: ADORA2A

Ensembl ID: ENSG00000128271

Description: adenosine A2a receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 12.1036
    Cell Significance Index: -3.0700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 2.4818
    Cell Significance Index: -3.0600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 2.2559
    Cell Significance Index: 13.6300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.7451
    Cell Significance Index: 77.1900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.5985
    Cell Significance Index: 13.0400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.8023
    Cell Significance Index: 25.7000
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.7853
    Cell Significance Index: 5.6400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3491
    Cell Significance Index: 15.8300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3067
    Cell Significance Index: 58.3700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2169
    Cell Significance Index: 6.3700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1999
    Cell Significance Index: 23.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1660
    Cell Significance Index: 3.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1636
    Cell Significance Index: 16.1900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.1414
    Cell Significance Index: 2.3300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1408
    Cell Significance Index: 127.1300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1367
    Cell Significance Index: 27.4300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1216
    Cell Significance Index: 7.3000
  • Cell Name: centroblast (CL0009112)
    Fold Change: 0.1072
    Cell Significance Index: 0.2500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1066
    Cell Significance Index: 11.5900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0894
    Cell Significance Index: 14.5500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0800
    Cell Significance Index: 2.0000
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0715
    Cell Significance Index: 0.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0513
    Cell Significance Index: 3.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0495
    Cell Significance Index: 17.7700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0412
    Cell Significance Index: 1.1800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0206
    Cell Significance Index: 0.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0160
    Cell Significance Index: 0.4600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0130
    Cell Significance Index: 0.2700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0103
    Cell Significance Index: 0.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0099
    Cell Significance Index: 0.7600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0094
    Cell Significance Index: 1.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0051
    Cell Significance Index: 0.1800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0030
    Cell Significance Index: -2.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0037
    Cell Significance Index: -2.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0041
    Cell Significance Index: -3.1300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0055
    Cell Significance Index: -3.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0064
    Cell Significance Index: -3.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0065
    Cell Significance Index: -1.1700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0073
    Cell Significance Index: -0.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0075
    Cell Significance Index: -3.4100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0087
    Cell Significance Index: -2.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0111
    Cell Significance Index: -0.2400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0130
    Cell Significance Index: -2.7300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0137
    Cell Significance Index: -0.7700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0167
    Cell Significance Index: -2.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0189
    Cell Significance Index: -2.3200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0197
    Cell Significance Index: -1.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0218
    Cell Significance Index: -2.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0228
    Cell Significance Index: -3.8900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0268
    Cell Significance Index: -0.4500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0278
    Cell Significance Index: -0.3900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0289
    Cell Significance Index: -1.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0300
    Cell Significance Index: -3.4400
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.0316
    Cell Significance Index: -0.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0318
    Cell Significance Index: -1.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0321
    Cell Significance Index: -4.1500
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0356
    Cell Significance Index: -0.5000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0417
    Cell Significance Index: -4.2600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0449
    Cell Significance Index: -1.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0528
    Cell Significance Index: -2.4800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0556
    Cell Significance Index: -1.4900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0577
    Cell Significance Index: -2.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0585
    Cell Significance Index: -4.3600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0608
    Cell Significance Index: -0.8700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0626
    Cell Significance Index: -1.3700
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0628
    Cell Significance Index: -0.2900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0632
    Cell Significance Index: -1.6900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0650
    Cell Significance Index: -2.8300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0695
    Cell Significance Index: -4.4900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0719
    Cell Significance Index: -2.5200
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0763
    Cell Significance Index: -1.0300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0812
    Cell Significance Index: -2.2700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0834
    Cell Significance Index: -2.7300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0867
    Cell Significance Index: -2.0800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0909
    Cell Significance Index: -1.9300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0930
    Cell Significance Index: -1.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0930
    Cell Significance Index: -2.3900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0936
    Cell Significance Index: -2.9800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1009
    Cell Significance Index: -2.1800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1022
    Cell Significance Index: -2.0800
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.1023
    Cell Significance Index: -1.1300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1051
    Cell Significance Index: -2.1100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1055
    Cell Significance Index: -1.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1072
    Cell Significance Index: -2.8200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1095
    Cell Significance Index: -2.7300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1122
    Cell Significance Index: -2.8000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1128
    Cell Significance Index: -1.9500
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.1163
    Cell Significance Index: -1.7400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1187
    Cell Significance Index: -1.6200
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: -0.1190
    Cell Significance Index: -0.9700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1194
    Cell Significance Index: -2.3600
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1210
    Cell Significance Index: -1.7200
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.1228
    Cell Significance Index: -1.3400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1236
    Cell Significance Index: -1.5600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1239
    Cell Significance Index: -2.2900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1239
    Cell Significance Index: -1.6200
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: -0.1274
    Cell Significance Index: -1.1800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1285
    Cell Significance Index: -2.6900
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.1302
    Cell Significance Index: -1.2200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1323
    Cell Significance Index: -1.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** The ADORA2A gene encodes for a G-protein coupled receptor with a molecular weight of approximately 40 kDa. The receptor consists of seven transmembrane domains and is activated by adenosine, a purine nucleoside. 2. **Ligand Binding:** The ADORA2A receptor is specifically activated by adenosine, which binds to the extracellular domain of the receptor, leading to the activation of the G-protein coupled signaling pathway. 3. **Signaling Pathways:** The ADORA2A receptor is involved in various signaling pathways, including the activation of adenylate cyclase, regulation of calcium ion transport, and modulation of protein kinase C activity. 4. **Expression:** The ADORA2A gene is significantly expressed in various cell types, including immune cells, endothelial cells, and neurons. **Pathways and Functions:** The ADORA2A receptor is involved in numerous signaling pathways, including: 1. **Adenylate Cyclase-Activating G Protein-Coupled Receptor Signaling Pathway:** The ADORA2A receptor activates adenylate cyclase, leading to the production of cyclic AMP (cAMP), which in turn activates protein kinase A (PKA) and modulates various cellular processes. 2. **Adenylate Cyclase-Modulating G Protein-Coupled Receptor Signaling Pathway:** The ADORA2A receptor modulates adenylate cyclase activity, influencing the production of cAMP and subsequent signaling events. 3. **Alpha-Actinin Binding:** The ADORA2A receptor interacts with alpha-actinin, a cytoskeletal protein, which regulates the stability and organization of actin filaments. 4. **Apoptotic Process:** The ADORA2A receptor modulates the apoptotic process by regulating the activity of pro-apoptotic and anti-apoptotic proteins. 5. **Neurotransmission:** The ADORA2A receptor is involved in the regulation of neurotransmission, particularly in the modulation of glutamatergic and GABAergic neurotransmission. **Clinical Significance:** The ADORA2A gene has been implicated in various diseases and disorders, including: 1. **Neurodegenerative Diseases:** The ADORA2A receptor has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where it modulates neurotransmission and synaptic plasticity. 2. **Cancer:** The ADORA2A receptor has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer, where it promotes tumor growth and metastasis. 3. **Inflammatory Disorders:** The ADORA2A receptor is involved in the regulation of inflammatory responses, and its dysregulation has been implicated in various inflammatory disorders, including rheumatoid arthritis and asthma. 4. **Cardiovascular Disease:** The ADORA2A receptor modulates cardiovascular function, and its dysregulation has been implicated in the pathogenesis of cardiovascular disease, including hypertension and atherosclerosis. In conclusion, the ADORA2A gene encodes for a G-protein coupled receptor that plays a crucial role in various physiological and pathological processes. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of further research into the mechanisms of ADORA2A signaling and its potential therapeutic applications.

Genular Protein ID: 4080930424

Symbol: AA2AR_HUMAN

Name: Adenosine receptor A2a

UniProtKB Accession Codes:

P29274 B2R7E0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 21 DrugCentral 1 EMBL 11 EMDB 3 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 68 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 77 PDBsum 77 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 1331670

Title: Molecular characterization of a human brain adenosine A2 receptor.

PubMed ID: 1331670

DOI: 10.1016/0169-328x(92)90152-2

PubMed ID: 8670304

Title: Characterization and chromosomal localization of the human A2a adenosine receptor gene: ADORA2A.

PubMed ID: 8670304

DOI: 10.1006/bbrc.1996.0916

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17689978

Title: The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor.

PubMed ID: 17689978

DOI: 10.1016/j.mcn.2007.05.007

PubMed ID: 20836733

Title: The dopamine D(4) receptor, the ultimate disordered protein.

PubMed ID: 20836733

DOI: 10.3109/10799893.2010.513842

PubMed ID: 7775460

Title: Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.

PubMed ID: 7775460

DOI: 10.1074/jbc.270.23.13987

PubMed ID: 16339847

Title: The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor.

PubMed ID: 16339847

DOI: 10.1124/mol.105.015818

PubMed ID: 18832607

Title: The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

PubMed ID: 18832607

DOI: 10.1126/science.1164772

PubMed ID: 21593763

Title: Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation.

PubMed ID: 21593763

DOI: 10.1038/nature10136

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

Sequence Information:

  • Length: 412
  • Mass: 44707
  • Checksum: 9438E9D64A6BE61B
  • Sequence:
    • MPIMGSSVYI TVELAIAVLA ILGNVLVCWA VWLNSNLQNV TNYFVVSLAA ADIAVGVLAI 
PFAITISTGF CAACHGCLFI ACFVLVLTQS SIFSLLAIAI DRYIAIRIPL RYNGLVTGTR 
AKGIIAICWV LSFAIGLTPM LGWNNCGQPK EGKNHSQGCG EGQVACLFED VVPMNYMVYF 
NFFACVLVPL LLMLGVYLRI FLAARRQLKQ MESQPLPGER ARSTLQKEVH AAKSLAIIVG 
LFALCWLPLH IINCFTFFCP DCSHAPLWLM YLAIVLSHTN SVVNPFIYAY RIREFRQTFR 
KIIRSHVLRQ QEPFKAAGTS ARVLAAHGSD GEQVSLRLNG HPPGVWANGS APHPERRPNG 
YALGLVSGGS AQESQGNTGL PDVELLSHEL KGVCPEPPGL DDPLAQDGAG VS

Genular Protein ID: 2512058737

Symbol: A8K1F6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K1F6

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 RefSeq 2 RuleBase 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 412
  • Mass: 44647
  • Checksum: 94255F04DDE1C75E
  • Sequence:
    • MPIMGSSVYI TVELAIAVLA ILGNVLVCWA VWLNSNLQNV TNYFVVSLAA ADIAVGVLAI 
PFAITISTGF CAACHGCLFI ACFVLVLTQS SIFSLLAIAI DRYIAIRIPL RYNGLVTGTR 
AKGIIAICWV LSFAIGLTPM LGWNNCGQPK EGKNHSQGCG EGQVACLFED VVPMNYMVYF 
NFFACVLVPL LLMLGVYLRI FLAARRQLKQ MESQPLPGER ARSTLQKEVH AAKSLAIIVG 
LFALCWLPLH IINCFTSFCP DCSHAPLWLM YLAIVLSHTN SVVNPFIYAY RIREFRQTFR 
KIIRSHVLRQ QEPFKAAGTS ARVLAAHGSD GEQVSLRLNG HPPGVWANGS APHPERRPNG 
YALGLVSGGS AQESQGNTGL PDVELLSHEL KGVCPEPPGL DDPLAQDGAG VS

Genular Protein ID: 3403555348

Symbol: B3KVQ4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KVQ4

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 412
  • Mass: 44721
  • Checksum: 712F5F0900CEACB2
  • Sequence:
    • MPIMGSSVYI TVELAIAVLA ILGNVLVCWA VWLNSNLQNV TNYFLVSLAA ADIAVGVLAI 
PFAITISTGF CAACHGCLFI ACFVLVLTQS SIFSLLAIAI DRYIAIRIPL RYNGLVTGTR 
AKGIIAICWV LSFAIGLTPM LGWNNCGQPK EGKNHSQGCG EGQVACLFED VVPMNYMVYF 
NFFACVLVPL LLMLGVYLRI FLAARRQLKQ MESQPLPGER ARSTLQKEVH AAKSLAIIVG 
LFALCWLPLH IINCFTFFCP DCSHAPLWLM YLAIVLSHTN SVVNPFIYAY RIREFRQTFR 
KIIRSHVLRQ QEPFKAAGTS ARVLAAHGSD GEQVSLRLNG HPPGVWANGS APHPERRPNG 
YALGLVSGGS AQESQGNTGL PDVELLSHEL KGVCPEPPGL DDPLAQDGAG VS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.