COX8A | ENSG00000176340 | NCBI 1351

Details for: COX8A

Gene ID: 1351

Symbol: COX8A

Ensembl ID: ENSG00000176340

Description: cytochrome c oxidase subunit 8A

Associated with

Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to chemical stress
(R-HSA-9711123)
Cytoprotection by hmox1
(R-HSA-9707564)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Metabolism
(R-HSA-1430728)
Respiratory electron transport
(R-HSA-611105)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-HSA-163200)
Rna polymerase ii transcription
(R-HSA-73857)
The citric acid (tca) cycle and respiratory electron transport
(R-HSA-1428517)
Tp53 regulates metabolic genes
(R-HSA-5628897)
Transcriptional regulation by tp53
(R-HSA-3700989)
Cellular respiration
(GO:0045333)
Cytochrome-c oxidase activity
(GO:0004129)
Generation of precursor metabolites and energy
(GO:0006091)
Mitochondrial electron transport, cytochrome c to oxygen
(GO:0006123)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial membrane
(GO:0031966)
Mitochondrial respiratory chain complex iv
(GO:0005751)
Mitochondrion
(GO:0005739)
Protein binding
(GO:0005515)
Proton transmembrane transport
(GO:1902600)
Respiratory chain complex iv
(GO:0045277)

Other Information

Proteins

Cytochrome c oxidase subunit 8A, mitochondrial

Genular Protein ID: 828621175

Symbol: COX8A_HUMAN

Name: Cytochrome c oxidase subunit 8A, mitochondrial

UniProtKB Accession Codes:

P10176 P15955

Database IDs:

Citations:

PubMed ID: 2543673

Title: A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non-muscle tissues.

PubMed ID: 2543673

DOI: 10.1016/s0021-9258(18)81662-3

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2847943

Title: Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence.

PubMed ID: 2847943

DOI: 10.1016/0014-5793(88)80353-3

PubMed ID: 26685157

Title: Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy.

PubMed ID: 26685157

DOI: 10.1093/brain/awv357

PubMed ID: 28844695

Title: Architecture of human mitochondrial respiratory megacomplex I2III2IV2.

PubMed ID: 28844695

DOI: 10.1016/j.cell.2017.07.050

PubMed ID: 30030519

Title: Structure of the intact 14-subunit human cytochrome c oxidase.

PubMed ID: 30030519

DOI: 10.1038/s41422-018-0071-1

Sequence Information:

Length: 69
Mass: 7579
Checksum: E1736E52AD0F76E2
Sequence:

MSVLTPLLLR GLTGSARRLP VPRAKIHSLP PEGKLGIMEL AVGLTSCFVT FLLPAGWILS 
HLETYRRPE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: COX8A

Associated with

Other Information

A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non-muscle tissues. PubMed ID: 2543673

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence. PubMed ID: 2847943

Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy. PubMed ID: 26685157

Architecture of human mitochondrial respiratory megacomplex I2III2IV2. PubMed ID: 28844695