Genular: Defining Cellular Identity and Function

Details for: Dsg1a

Gene ID: 13510

Symbol: Dsg1a

Ensembl ID: ENSMUSG00000069441

Description: desmoglein 1 alpha

Associated with

Apoptosis
(R-MMU-109581)
Apoptotic cleavage of cell adhesion proteins
(R-MMU-351906)
Apoptotic cleavage of cellular proteins
(R-MMU-111465)
Apoptotic execution phase
(R-MMU-75153)
Developmental biology
(R-MMU-1266738)
Formation of the cornified envelope
(R-MMU-6809371)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Keratinization
(R-MMU-6805567)
Neutrophil degranulation
(R-MMU-6798695)
Programmed cell death
(R-MMU-5357801)
Rho gtpase cycle
(R-MMU-9012999)
Rnd2 gtpase cycle
(R-MMU-9696270)
Rnd3 gtpase cycle
(R-MMU-9696264)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Anchoring junction
(GO:0070161)
Apical plasma membrane
(GO:0016324)
Calcium ion binding
(GO:0005509)
Cell-cell adhesion
(GO:0098609)
Cell-cell junction
(GO:0005911)
Cell adhesion
(GO:0007155)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Desmosome
(GO:0030057)
Gamma-catenin binding
(GO:0045295)
Homophilic cell adhesion via plasma membrane adhesion molecules
(GO:0007156)
Lateral plasma membrane
(GO:0016328)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein stabilization
(GO:0050821)

Other Information

Proteins

Desmoglein-1-alpha

Genular Protein ID: 2548441677

Symbol: DSG1A_MOUSE

Name: Desmoglein-1-alpha

UniProtKB Accession Codes:

Q61495 A8WFQ4 Q8CE03

Database IDs:

Citations:

PubMed ID: 11994138

Title: Interspecies conservation and differential expression of mouse desmoglein gene family.

PubMed ID: 11994138

DOI: 10.1034/j.1600-0625.2002.110203.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7959727

Title: Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18.

PubMed ID: 7959727

DOI: 10.1006/geno.1994.1309

PubMed ID: 12631242

Title: Novel member of the mouse desmoglein gene family: Dsg1-beta.

PubMed ID: 12631242

DOI: 10.1034/j.1600-0625.2003.120102.x

Sequence Information:

Length: 1057
Mass: 114597
Checksum: EEF6AF26E57051A0
Sequence:

MDWHSFRIAA LLLTSLVVLE VNSEFQIQVR DHNAKNGTIK WHSIRRQKRE WIKFAAACRE 
GEDNSKRNPI AKIHSDCAAN QPVTYRISGV GIDQPPYGIF IINQKTGEIN ITSIVDREVT 
PFFIIYCRAL NAQGQDLENP LELRVRVMDI NDNPPVFSMT TFLGQIEENS NANTLVMKLN 
ATDADEPNNL NSMIAFKIIR QEPSDSPMFI INRKTGEIRT MNNFLDREQY SQYSLVVRGS 
DRDGGADGMS AESECSITIL DVNDNIPYLE QSSYDITIEE NALHSQLVQI RVIDLDEEFS 
DNWKAIIFFI SGNEGNWFEI EMNERTNVGT LKVVKPLDYE AMKNLQLSIG VRNVAEFHQS 
IISQYRLTAT MVTVTVLNVI EGSVFRPGSK TFVVDSRMEA NHRVGEFVAT DLDTGRASTN 
VRYEMGNNPE NLLVVDSRTG IITLRNRVTM EQYQRLNGEY KGTVLSIDDS LQRTCTGTIV 
IELSGTGWVT GSESGGSSSG SGDDRDRVTN GYQGTSSTEN PQRVTGSWGG SGIDGTRPNT 
NPFQGDPDET LETPLYGDNV HFGPAGIGLL IMGFLVLGLV PFLLICCDCG GAPGGGAGFE 
PVPECSDGAI HTWAVEGPQP EPHEGITTIC VPQMPPGNAN VIEYIDNSGV YTNEYCGREM 
QDLGGGERTT GFELMDGVKT SAAPEICQEY SGTLRRNSMR ECRDGGLNMN FMESYFCQKA 
YAYADEDEGR PSNDCLLIYD IEGVGSPAGS VGCCSFIGED LDESFLDTLG PKFKKLADIS 
LGKEIDSYPD SDPSWPPQST EPMCPQHTEP LGSGHPPISP HFGTTTVISE NAYHSGPGVQ 
HPVPIPDPLG YGNVTVRESY TTSGTLKPSV HFHDNQQASN VVVTERVVGP ISGADLHGML 
EIPDLRGGAN VIVTERVIAP GSSLPTSLTI PNPQETSNVV VTERVIQPTS GMIGNLSMTP 
ELSSAHNVIV TERVVSGAGM SEIAGTAGLG GVGGIGSSGL VSTTMGASGT GLNMGGTATI 
GHMRSSSDHH FSQTVGSASP SMARSRITKY NTVQYSK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dsg1a

Associated with

Other Information

Interspecies conservation and differential expression of mouse desmoglein gene family. PubMed ID: 11994138

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072