Genular: Defining Cellular Identity and Function

Details for: Dsg2

Gene ID: 13511

Symbol: Dsg2

Ensembl ID: ENSMUSG00000044393

Description: desmoglein 2

Associated with

Apoptosis
(R-MMU-109581)
Apoptotic cleavage of cell adhesion proteins
(R-MMU-351906)
Apoptotic cleavage of cellular proteins
(R-MMU-111465)
Apoptotic execution phase
(R-MMU-75153)
Developmental biology
(R-MMU-1266738)
Formation of the cornified envelope
(R-MMU-6809371)
Keratinization
(R-MMU-6805567)
Programmed cell death
(R-MMU-5357801)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Anchoring junction
(GO:0070161)
Apical plasma membrane
(GO:0016324)
Bundle of his cell-purkinje myocyte adhesion involved in cell communication
(GO:0086073)
Calcium ion binding
(GO:0005509)
Cell-cell adhesion
(GO:0098609)
Cell adhesion
(GO:0007155)
Cell adhesion molecule binding
(GO:0050839)
Cell junction
(GO:0030054)
Desmosome
(GO:0030057)
Desmosome organization
(GO:0002934)
Homophilic cell adhesion via plasma membrane adhesion molecules
(GO:0007156)
Intercalated disc
(GO:0014704)
Intracellular membrane-bounded organelle
(GO:0043231)
Lateral plasma membrane
(GO:0016328)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Plasma membrane
(GO:0005886)
Purkinje myocyte development
(GO:0003165)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of ventricular cardiac muscle cell action potential
(GO:0098911)

Other Information

Proteins

Desmoglein-2

Genular Protein ID: 383540176

Symbol: DSG2_MOUSE

Name: Desmoglein-2

UniProtKB Accession Codes:

O55111 A2RRJ0 Q8K069 Q8R517

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9404003

Title: Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse.

PubMed ID: 9404003

DOI: 10.1046/j.1432-0436.1997.6220083.x

PubMed ID: 12787123

Title: Genomic sequence analysis of the mouse desmoglein cluster reveals evidence for six distinct genes: characterization of mouse DSG4, DSG5, and DSG6.

PubMed ID: 12787123

DOI: 10.1046/j.1523-1747.2003.12257.x

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1122
Mass: 122385
Checksum: 9EB9CD402632437A
Sequence:

MARSPGDRCA LLLLVQLLAV VCLDFGNGLH LEVFSPRNEG KPFPKHTHLV RQKRAWITAP 
VALREGEDLS RKNPIAKIHS DLAEEKGIKI TYKYTGKGIT EPPFGIFVFD RNTGELNITS 
ILDREETPYF LLTGYALDSR GNNLEKPLEL RIKVLDINDN EPVFTQEVFV GSIEELSAAH 
TLVMKITATD ADDPETLNAK VSYRIVSQEP ANSHMFYLNK DTGEIYTTSF TLDREEHSSY 
SLTVEARDGN GQITDKPVQQ AQVQIRILDV NDNIPVVENK MYEGTVEENQ VNVEVMRIKV 
TDADEVGSDN WLANFTFASG NEGGYFHIET DTQTNEGIVT LVKEVDYEEM KKLDLSIIVT 
NKAAFHKSIL SKYKATPIPI TVKVKNVVEG IHFKSSVVSF RASEAMDRSS LSRSIGNFQV 
FDEDTGQAAK VTYVKVQDTD NWVSVDSVTS EIKLVKIPDF ESRYVQNGTY TAKVVAISKE 
HPQKTITGTI VITVEDVNDN CPVLVDSVRS VCEDEPYVNV TAEDLDGAQN SAPFSFSIID 
QPPGTAQKWK ITHQESTSVL LQQSERKRGR SEIPFLISDS QGFSCPERQV LQLTVCECLK 
GGGCVAAQYD NYVGLGPAAI ALMILALLLL LLVPLLLLIC HCGGGAKGFT PIPGTIEMLH 
PWNNEGAPPE DKVVPSLLVA DHAESSAVRG GVGGAMLKEG MMKGSSSASV TKGQHELSEV 
DGRWEEHRSL LTAGATHHVR TAGTIAANEA VRTRATGSSR DMSGARGAVA VNEEFLRSYF 
TEKAASYNGE DDLHMAKDCL LVYSQEDTAS LRGSVGCCSF IEGELDDLFL DDLGLKFKTL 
AEVCLGRKID LDVDIEQRQK PVREASVSAA SGSHYEQAVT SSESAYSSNT GFPAPKPLHE 
VHTEKVTQEI VTESSVSSRQ SQKVVPPPDP VASGNIIVTE TSYAKGSAVP PSTVLLAPRQ 
PQSLIVTERV YAPTSTLVDQ HYANEEKVLV TERVIQPNGG IPKPLEVTQH LKDAQYVMVR 
ERESILAPSS GVQPTLAMPS VAAGGQNVTV TERILTPAST LQSSYQIPSE TSITARNTVL 
SSVGSIGPLP NLDLEESDRP NSTITTSSTR VTKHSTMQHS YS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dsg2

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. PubMed ID: 9404003

Genomic sequence analysis of the mouse desmoglein cluster reveals evidence for six distinct genes: characterization of mouse DSG4, DSG5, and DSG6. PubMed ID: 12787123