Genular: Defining Cellular Identity and Function

Details for: E2f1

Gene ID: 13555

Symbol: E2f1

Ensembl ID: ENSMUSG00000027490

Description: E2F transcription factor 1

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cyclin d associated events in g1
(R-MMU-69231)
G1 phase
(R-MMU-69236)
G2 phase
(R-MMU-68911)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Mitotic g2-g2/m phases
(R-MMU-453274)
Anoikis
(GO:0043276)
Apoptotic process
(GO:0006915)
Cell cycle
(GO:0007049)
Cellular response to nerve growth factor stimulus
(GO:1990090)
Cellular response to xenobiotic stimulus
(GO:0071466)
Centrosome
(GO:0005813)
Chromatin
(GO:0000785)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity
(GO:0001216)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna-templated transcription
(GO:0006351)
Dna binding
(GO:0003677)
Dna damage checkpoint signaling
(GO:0000077)
Forebrain development
(GO:0030900)
Intrinsic apoptotic signaling pathway by p53 class mediator
(GO:0072332)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Lens fiber cell apoptotic process
(GO:1990086)
Molecular adaptor activity
(GO:0060090)
Mrna stabilization
(GO:0048255)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of dna binding
(GO:0043392)
Negative regulation of fat cell differentiation
(GO:0045599)
Negative regulation of fat cell proliferation
(GO:0070345)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear chromosome
(GO:0000228)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of fibroblast proliferation
(GO:0048146)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glial cell proliferation
(GO:0060252)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein kinase binding
(GO:0019901)
Rb-e2f complex
(GO:0035189)
Regulation of cell cycle
(GO:0051726)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

E2F1_MOUSE
Q9CYB4_MOUSE

Genular Protein ID: 16137683

Symbol: E2F1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q61501 Q80VZ3

Database IDs:

Citations:

PubMed ID: 8114719

Title: Cloning, chromosomal location, and characterization of mouse E2F1.

PubMed ID: 8114719

DOI: 10.1128/mcb.14.3.1861-1869.1994

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8336704

Title: A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity.

PubMed ID: 8336704

DOI: 10.1128/mcb.13.8.4588-4599.1993

PubMed ID: 9376316

Title: Expression patterns of the E2F family of transcription factors during mouse nervous system development.

PubMed ID: 9376316

DOI: 10.1016/s0925-4773(97)00083-x

PubMed ID: 9674698

Title: E2F-1-induced p53-independent apoptosis in transgenic mice.

PubMed ID: 9674698

DOI: 10.1038/sj.onc.1201915

PubMed ID: 11672531

Title: E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

PubMed ID: 11672531

DOI: 10.1016/s0092-8674(01)00516-5

PubMed ID: 15716352

Title: EAPP, a novel E2F binding protein that modulates E2F-dependent transcription.

PubMed ID: 15716352

DOI: 10.1091/mbc.e04-11-0975

PubMed ID: 20940255

Title: Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.

PubMed ID: 20940255

DOI: 10.1242/jcs.068924

PubMed ID: 20176812

Title: Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.

PubMed ID: 20176812

DOI: 10.1128/mcb.01619-09

Sequence Information:

Length: 430
Mass: 46323
Checksum: C5DF18AD3B4DFEFA
Sequence:

MAVAPAGGQH APALEALLGA GALRLLDSSQ IVIISTAPDV GAPQLPAAPP TGPRDSDVLL 
FATPQAPRPA PSAPRPALGR PPVKRRLDLE TDHQYLAGSS GPFRGRGRHP GKGVKSPGEK 
SRYETSLNLT TKRFLELLSR SADGVVDLNW AAEVLKVQKR RIYDITNVLE GIQLIAKKSK 
NHIQWLGSHT MVGIGKRLEG LTQDLQQLQE SEQQLDHLMH ICTTQLQLLS EDSDTQRLAY 
VTCQDLRSIA DPAEQMVIVI KAPPETQLQA VDSSETFQIS LKSKQGPIDV FLCPEESADG 
ISPGKTSCQE TSSGEDRTAD SGPAGPPPSP PSTSPALDPS QSLLGLEQEA VLPRMGHLRV 
PMEEDQLSPL VAADSLLEHV KEDFSGLLPG EFISLSPPHE ALDYHFGLEE GEGIRDLFDC 
DFGDLTPLDF

Genular Protein ID: 1069893159

Symbol: Q9CYB4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CYB4

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 385
Mass: 42323
Checksum: EE01605F07E24578
Sequence:

MGKCFTQLQM VGLIFELMSA GLLQNLWLGS AHSCLLEVKR RLDLETDHQY LAGSSGPFRG 
RGRHPGKGVK SPGEKSRYET SLNLTTKRFL ELLSRSADGV VDLNWAAEVL KVQKRRIYDI 
TNVLEGIQLI AKKSKNHIQW LGSHTMVGIG KRLEGLTQDL QQLQESEQQL DHLMHICTTQ 
LQLLSEDSDT QRLAYVTCQD LRSIADPAEQ MVIVIKAPPE TQLQAVDSSE TFQISLKSKQ 
GPIDVFLCPE ESADGISPGK TSCQETSSGE DRTADSGPAG PPPSPPSTSP ALDPSQSLLG 
LEQEAVLPRM GHLRVPMEED QLSPLVAADS LLEHVKEDFS GLLPGEFISL SPPHEALDYH 
FGLEEGEGIR DLFDCDFGDL TPLDF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: E2f1

Associated with

Other Information

Cloning, chromosomal location, and characterization of mouse E2F1. PubMed ID: 8114719

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity. PubMed ID: 8336704

Expression patterns of the E2F family of transcription factors during mouse nervous system development. PubMed ID: 9376316

E2F-1-induced p53-independent apoptosis in transgenic mice. PubMed ID: 9674698

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. PubMed ID: 11672531

EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. PubMed ID: 15716352

Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation. PubMed ID: 20940255

Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes. PubMed ID: 20176812

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303