CP | ENSG00000047457 | NCBI 1356

Details for: CP

Gene ID: 1356

Symbol: CP

Ensembl ID: ENSG00000047457

Description: ceruloplasmin

Associated with

Defective cp causes aceruloplasminemia (acerulop)
(R-HSA-5619060)
Defective slc40a1 causes hemochromatosis 4 (hfe4) (macrophages)
(R-HSA-5619049)
Disease
(R-HSA-1643685)
Disorders of transmembrane transporters
(R-HSA-5619115)
Iron uptake and transport
(R-HSA-917937)
Metabolism of proteins
(R-HSA-392499)
Metal ion slc transporters
(R-HSA-425410)
Post-translational protein modification
(R-HSA-597592)
Post-translational protein phosphorylation
(R-HSA-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-HSA-381426)
Slc-mediated transmembrane transport
(R-HSA-425407)
Slc transporter disorders
(R-HSA-5619102)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-HSA-425366)
Transport of small molecules
(R-HSA-382551)
Blood microparticle
(GO:0072562)
Cellular oxidant detoxification
(GO:0098869)
Copper ion binding
(GO:0005507)
Copper ion transport
(GO:0006825)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Ferroxidase activity
(GO:0004322)
Glutathione peroxidase activity
(GO:0004602)
Intracellular copper ion homeostasis
(GO:0006878)
Intracellular iron ion homeostasis
(GO:0006879)
Iron ion transport
(GO:0006826)
Lysosomal membrane
(GO:0005765)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on metal ions, oxygen as acceptor
(GO:0016724)
Phospholipid-hydroperoxide glutathione peroxidase activity
(GO:0047066)
Plasma membrane
(GO:0005886)
Protein-folding chaperone binding
(GO:0051087)
Side of membrane
(GO:0098552)

Other Information

Proteins

Ceruloplasmin
A5PL27_HUMAN

Genular Protein ID: 1840105270

Symbol: CERU_HUMAN

Name: Ceruloplasmin

UniProtKB Accession Codes:

P00450 Q14063 Q2PP18 Q9UKS4

Database IDs:

Citations:

PubMed ID: 2873574

Title: Complete cDNA sequence of human preceruloplasmin.

PubMed ID: 2873574

DOI: 10.1073/pnas.83.14.5086

PubMed ID: 7702601

Title: Fine structure of the human ceruloplasmin gene.

PubMed ID: 7702601

DOI: 10.1006/bbrc.1995.1437

PubMed ID: 3755405

Title: Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence.

PubMed ID: 3755405

DOI: 10.1016/0014-5793(86)80739-6

PubMed ID: 3486416

Title: Characterization, mapping, and expression of the human ceruloplasmin gene.

PubMed ID: 3486416

DOI: 10.1073/pnas.83.10.3257

PubMed ID: 6582496

Title: Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule.

PubMed ID: 6582496

DOI: 10.1073/pnas.81.2.390

PubMed ID: 6571985

Title: Internal triplication in the structure of human ceruloplasmin.

PubMed ID: 6571985

DOI: 10.1073/pnas.80.1.115

PubMed ID: 6940148

Title: Complete amino acid sequence of a 50,000-dalton fragment of human ceruloplasmin.

PubMed ID: 6940148

DOI: 10.1073/pnas.78.2.790

PubMed ID: 6987229

Title: Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. I. Amino acid sequence of the cyanogen bromide peptides.

PubMed ID: 6987229

DOI: 10.1016/s0021-9258(19)85822-2

PubMed ID: 6987230

Title: Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. II. Amino acid sequence of the tryptic peptides.

PubMed ID: 6987230

DOI: 10.1016/s0021-9258(19)85823-4

PubMed ID: 2355023

Title: Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing.

PubMed ID: 2355023

DOI: 10.1016/s0021-9258(18)87015-6

PubMed ID: 12055353

Title: Ceruloplasmin metabolism and function.

PubMed ID: 12055353

DOI: 10.1146/annurev.nutr.22.012502.114457

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 17242517

Title: Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites.

PubMed ID: 17242517

DOI: 10.1107/s090744490604947x

PubMed ID: 15557511

Title: Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease.

PubMed ID: 15557511

DOI: 10.1212/01.wnl.0000144276.29988.c3

PubMed ID: 16150804

Title: Functional relevance of ceruloplasmin mutations in Parkinson's disease.

PubMed ID: 16150804

DOI: 10.1096/fj.04-3486fje

Sequence Information:

Length: 1065
Mass: 122219
Checksum: 2F2F76BB47D30F58
Sequence:

MKILILGIFL FLCSTPAWAK EKHYYIGIIE TTWDYASDHG EKKLISVDTE HSNIYLQNGP 
DRIGRLYKKA LYLQYTDETF RTTIEKPVWL GFLGPIIKAE TGDKVYVHLK NLASRPYTFH 
SHGITYYKEH EGAIYPDNTT DFQRADDKVY PGEQYTYMLL ATEEQSPGEG DGNCVTRIYH 
SHIDAPKDIA SGLIGPLIIC KKDSLDKEKE KHIDREFVVM FSVVDENFSW YLEDNIKTYC 
SEPEKVDKDN EDFQESNRMY SVNGYTFGSL PGLSMCAEDR VKWYLFGMGN EVDVHAAFFH 
GQALTNKNYR IDTINLFPAT LFDAYMVAQN PGEWMLSCQN LNHLKAGLQA FFQVQECNKS 
SSKDNIRGKH VRHYYIAAEE IIWNYAPSGI DIFTKENLTA PGSDSAVFFE QGTTRIGGSY 
KKLVYREYTD ASFTNRKERG PEEEHLGILG PVIWAEVGDT IRVTFHNKGA YPLSIEPIGV 
RFNKNNEGTY YSPNYNPQSR SVPPSASHVA PTETFTYEWT VPKEVGPTNA DPVCLAKMYY 
SAVEPTKDIF TGLIGPMKIC KKGSLHANGR QKDVDKEFYL FPTVFDENES LLLEDNIRMF 
TTAPDQVDKE DEDFQESNKM HSMNGFMYGN QPGLTMCKGD SVVWYLFSAG NEADVHGIYF 
SGNTYLWRGE RRDTANLFPQ TSLTLHMWPD TEGTFNVECL TTDHYTGGMK QKYTVNQCRR 
QSEDSTFYLG ERTYYIAAVE VEWDYSPQRE WEKELHHLQE QNVSNAFLDK GEFYIGSKYK 
KVVYRQYTDS TFRVPVERKA EEEHLGILGP QLHADVGDKV KIIFKNMATR PYSIHAHGVQ 
TESSTVTPTL PGETLTYVWK IPERSGAGTE DSACIPWAYY STVDQVKDLY SGLIGPLIVC 
RRPYLKVFNP RRKLEFALLF LVFDENESWY LDDNIKTYSD HPEKVNKDDE EFIESNKMHA 
INGRMFGNLQ GLTMHVGDEV NWYLMGMGNE IDLHTVHFHG HSFQYKHRGV YSSDVFDIFP 
GTYQTLEMFP RTPGIWLLHC HVTDHIHAGM ETTYTVLQNE DTKSG

Genular Protein ID: 786062727

Symbol: A5PL27_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5PL27

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 1065
Mass: 122205
Checksum: 2F2F1294E2D30F58
Sequence:

MKILILGIFL FLCSTPAWAK EKHYYIGIIE TTWDYASDHG EKKLISVDTE HSNIYLQNGP 
DRIGRLYKKA LYLQYTDETF RTTIEKPVWL GFLGPIIKAE TGDKVYVHLK NLASRPYTFH 
SHGITYYKEH EGAIYPDNTT DFQRADDKVY PGEQYTYMLL ATEEQSPGEG DGNCVTRIYH 
SHIDAPKDIA SGLIGPLIIC KKDSLDKEKE KHIDREFVVM FSVVDENFSW YLEDNIKTYC 
SEPEKVDKDN EDFQESNRMY SVNGYTFGSL PGLSMCAEDR VKWYLFGMGN EVDVHAAFFH 
GQALTNKNYR IDTINLFPAT LFDAYMVAQN PGEWMLSCQN LNHLKAGLQA FFQVQECNKS 
SSKDNIRGKH VRHYYIAAEE IIWNYAPSGI DIFTKENLTA PGSDSAVFFE QGTTRIGGSY 
KKLVYREYTD ASFTNRKERG PEEEHLGILG PVIWAEVGDT IRVTFHNKGA YPLSIEPIGV 
RFNKNNEGTY YSPNYNPQSR SVPPSASHVA PTETFTYEWT VPKEVGPTNA DPVCLAKMYY 
SAVDPTKDIF TGLIGPMKIC KKGSLHANGR QKDVDKEFYL FPTVFDENES LLLEDNIRMF 
TTAPDQVDKE DEDFQESNKM HSMNGFMYGN QPGLTMCKGD SVVWYLFSAG NEADVHGIYF 
SGNTYLWRGE RRDTANLFPQ TSLTLHMWPD TEGTFNVECL TTDHYTGGMK QKYTVNQCRR 
QSEDSTFYLG ERTYYIAAVE VEWDYSPQRE WEKELHHLQE QNVSNAFLDK GEFYIGSKYK 
KVVYRQYTDS TFRVPVERKA EEEHLGILGP QLHADVGDKV KIIFKNMATR PYSIHAHGVQ 
TESSTVTPTL PGETLTYVWK IPERSGAGTE DSACIPWAYY STVDQVKDLY SGLIGPLIVC 
RRPYLKVFNP RRKLEFALLF LVFDENESWY LDDNIKTYSD HPEKVNKDDE EFIESNKMHA 
INGRMFGNLQ GLTMHVGDEV NWYLMGMGNE IDLHTVHFHG HSFQYKHRGV YSSDVFDIFP 
GTYQTLEMFP RTPGIWLLHC HVTDHIHAGM ETTYTVLQNE DTKSG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CP

Associated with

Other Information

Complete cDNA sequence of human preceruloplasmin. PubMed ID: 2873574

Fine structure of the human ceruloplasmin gene. PubMed ID: 7702601

Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence. PubMed ID: 3755405

Characterization, mapping, and expression of the human ceruloplasmin gene. PubMed ID: 3486416

Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule. PubMed ID: 6582496

Internal triplication in the structure of human ceruloplasmin. PubMed ID: 6571985

Complete amino acid sequence of a 50,000-dalton fragment of human ceruloplasmin. PubMed ID: 6940148

Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. I. Amino acid sequence of the cyanogen bromide peptides. PubMed ID: 6987229

Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. II. Amino acid sequence of the tryptic peptides. PubMed ID: 6987230

Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing. PubMed ID: 2355023

Ceruloplasmin metabolism and function. PubMed ID: 12055353

A proteomic analysis of human bile. PubMed ID: 15084671

Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. PubMed ID: 14760718

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

A strategy for precise and large scale identification of core fucosylated glycoproteins. PubMed ID: 19139490

Enrichment of glycopeptides for glycan structure and attachment site identification. PubMed ID: 19838169

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

A single kinase generates the majority of the secreted phosphoproteome. PubMed ID: 26091039

Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites. PubMed ID: 17242517

Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease. PubMed ID: 15557511

Functional relevance of ceruloplasmin mutations in Parkinson's disease. PubMed ID: 16150804

The sequence of the human genome. PubMed ID: 11181995

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334