Genular: Defining Cellular Identity and Function

Details for: E4f1

Gene ID: 13560

Symbol: E4f1

Ensembl ID: ENSMUSG00000024137

Description: E4F transcription factor 1

Associated with

Camp response element binding
(GO:0035497)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Dna replication
(GO:0006260)
Embryo development
(GO:0009790)
Metal ion binding
(GO:0046872)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of cell cycle process
(GO:0010564)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of mitotic cell cycle, embryonic
(GO:0009794)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Spindle
(GO:0005819)
Transferase activity
(GO:0016740)

Other Information

Proteins

Transcription factor E4F1

Genular Protein ID: 2557796384

Symbol: E4F1_MOUSE

Name: Transcription factor E4F1

UniProtKB Accession Codes:

Q8CCE9 Q05BH7 Q3UNJ9 Q62065 Q6IR08 Q6PGI1 Q9QY56

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8262041

Title: Repression of adenovirus E1A enhancer activity by a novel zinc finger-containing DNA-binding protein related to the GLI-Kruppel protein.

PubMed ID: 8262041

DOI: 10.1002/j.1460-2075.1993.tb06192.x

PubMed ID: 9530632

Title: Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice.

PubMed ID: 9530632

DOI: 10.1007/s003359900758

PubMed ID: 10644996

Title: p53 is involved in the p120E4F-mediated growth arrest.

PubMed ID: 10644996

DOI: 10.1038/sj.onc.1203250

PubMed ID: 10869426

Title: pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F.

PubMed ID: 10869426

DOI: 10.1073/pnas.130198397

PubMed ID: 15226446

Title: The E4F protein is required for mitotic progression during embryonic cell cycles.

PubMed ID: 15226446

DOI: 10.1128/mcb.24.14.6467-6475.2004

PubMed ID: 17557114

Title: The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.

PubMed ID: 17557114

DOI: 10.1038/sj.embor.7400983

Sequence Information:

Length: 783
Mass: 84296
Checksum: 59E47F7A64A224A4
Sequence:

MEGAMAVRVT AAHTAEARAE AGREAGEGGV AAAAALSSGG FLGLPAPFSE EDEDDVHRCG 
RCQVEFTALE DFVQHKIQKT CHRAPQEALP TTPAATALLD QEVVPTAAEG GPDEPITVAH 
IVVEATSLAE DISHAPDLVG SGHIKEVIVA AEAEPGDVEM AEAPGSPNHQ ELGLLGEGEQ 
AHVKLLVNKE GRYVCMLCHK TFKTGSILKA HMVTHSSRKD HECKLCGASF RTKGSLIRHH 
RRHTDERPYK CAKCGKSFRE SGALTRHLKS LTPCTEKIRF SISKDTAVGK EEVPAGSSAS 
TVGTVTSSVA GDPMETSPVI HLVTDAKGTV IHEVHVQMQE LPLGMKALTP ESPDSEELPC 
SSENSRENLL HQAMQNSGIV LERVAGEESA LEPAPPSGSS PQCLGDGSPE LPLLKVEQIE 
TQVASEAATV PRTHPCPQCS ETFPTAATLE AHKRGHIAPR PFTCTQCGKA FPKAYLLKKH 
QEVHVHERRF RCGDCGKLYK TIAHVRGHRR VHSDERPFPC PQCGKRYKTK NAQQVHFRTH 
LEEKPHVCQF CSRGFREKGS LVRHVRHHTG EKPFKCYKCG RGFAEHGTLN RHLRTKGGCL 
LEVEELLVSE ESPSAAATVL AEDPHTVLVE FSSVVADTQE YIIEATADDT ETSEATEIIE 
GTQTEVDSHI MKVVQQIVHQ AGAGHQIIVQ NVTMDQETAL GSEATAADTI TIATPESLTE 
QVAMTLASAI SEGTVLTARA GPNSTEQATV TMVSSEDIEI LEHGGELVIA SPEGQLEVQT 
VIV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: E4f1

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Repression of adenovirus E1A enhancer activity by a novel zinc finger-containing DNA-binding protein related to the GLI-Kruppel protein. PubMed ID: 8262041

Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice. PubMed ID: 9530632

p53 is involved in the p120E4F-mediated growth arrest. PubMed ID: 10644996

pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F. PubMed ID: 10869426

The E4F protein is required for mitotic progression during embryonic cell cycles. PubMed ID: 15226446

The role of LANP and ataxin 1 in E4F-mediated transcriptional repression. PubMed ID: 17557114