Details for: CPA2

Gene ID: 1358

Symbol: CPA2

Ensembl ID: ENSG00000158516

Description: carboxypeptidase A2

Associated with

Other Information

Genular Protein ID: 2912044296

Symbol: CBPA2_HUMAN

Name: Carboxypeptidase A2

UniProtKB Accession Codes:

P48052 A4D1M4 C9JIK1 Q53XS1 Q96A12 Q96QN3 Q9UCF1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7896805

Title: The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model.

PubMed ID: 7896805

DOI: 10.1074/jbc.270.12.6651

PubMed ID: 8806703

Title: Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.

PubMed ID: 8806703

DOI: 10.1006/abbi.1996.0310

PubMed ID: 2920728

Title: Purification and properties of five different forms of human procarboxypeptidases.

PubMed ID: 2920728

DOI: 10.1111/j.1432-1033.1989.tb14590.x

PubMed ID: 8318831

Title: Separation of human pancreatic carboxypeptidase A isoenzymes by high performance liquid chromatography.

PubMed ID: 8318831

DOI: 10.1002/bmc.1130070308

PubMed ID: 9384570

Title: The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.

PubMed ID: 9384570

DOI: 10.1093/emboj/16.23.6906

PubMed ID: 9450539

Title: Characterisation and preliminary X-ray diffraction analysis of human pancreatic procarboxypeptidase A2.

PubMed ID: 9450539

DOI: 10.1016/s0014-5793(97)01476-2

PubMed ID: 10742178

Title: Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.

PubMed ID: 10742178

DOI: 10.1038/74092

PubMed ID: 12948494

Title: A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins.

PubMed ID: 12948494

DOI: 10.1016/s0022-2836(03)00888-x

PubMed ID: 12538893

Title: NMR solution structure of the activation domain of human procarboxypeptidase A2.

PubMed ID: 12538893

DOI: 10.1110/ps.0227303

Sequence Information:

  • Length: 419
  • Mass: 47030
  • Checksum: 00269F2AE50CA38D
  • Sequence:
    • MAMRLILFFG ALFGHIYCLE TFVGDQVLEI VPSNEEQIKN LLQLEAQEHL QLDFWKSPTT 
PGETAHVRVP FVNVQAVKVF LESQGIAYSI MIEDVQVLLD KENEEMLFNR RRERSGNFNF 
GAYHTLEEIS QEMDNLVAEH PGLVSKVNIG SSFENRPMNV LKFSTGGDKP AIWLDAGIHA 
REWVTQATAL WTANKIVSDY GKDPSITSIL DALDIFLLPV TNPDGYVFSQ TKNRMWRKTR 
SKVSGSLCVG VDPNRNWDAG FGGPGASSNP CSDSYHGPSA NSEVEVKSIV DFIKSHGKVK 
AFITLHSYSQ LLMFPYGYKC TKLDDFDELS EVAQKAAQSL RSLHGTKYKV GPICSVIYQA 
SGGSIDWSYD YGIKYSFAFE LRDTGRYGFL LPARQILPTA EETWLGLKAI MEHVRDHPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.