Mapre1 | ENSMUSG00000027479 | NCBI 13589

Details for: Mapre1

Gene ID: 13589

Symbol: Mapre1

Ensembl ID: ENSMUSG00000027479

Description: microtubule-associated protein, RP/EB family, member 1

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Anchoring of the basal body to the plasma membrane
(R-MMU-5620912)
Aurka activation by tpx2
(R-MMU-8854518)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Centrosome maturation
(R-MMU-380287)
Cilium assembly
(R-MMU-5617833)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
G2/m transition
(R-MMU-69275)
Loss of nlp from mitotic centrosomes
(R-MMU-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-MMU-380284)
Mitotic anaphase
(R-MMU-68882)
Mitotic g2-g2/m phases
(R-MMU-453274)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Recruitment of mitotic centrosome proteins and complexes
(R-MMU-380270)
Recruitment of numa to mitotic centrosomes
(R-MMU-380320)
Regulation of plk1 activity at g2/m transition
(R-MMU-2565942)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-MMU-8852276)
Attachment of mitotic spindle microtubules to kinetochore
(GO:0051315)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cell migration
(GO:0016477)
Cell projection
(GO:0042995)
Cell projection membrane
(GO:0031253)
Centrosome
(GO:0005813)
Ciliary basal body
(GO:0036064)
Cortical microtubule cytoskeleton
(GO:0030981)
Cytoplasm
(GO:0005737)
Cytoplasmic microtubule
(GO:0005881)
Cytoskeleton
(GO:0005856)
Establishment of mitotic spindle orientation
(GO:0000132)
Focal adhesion
(GO:0005925)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Microtubule
(GO:0005874)
Microtubule binding
(GO:0008017)
Microtubule bundle formation
(GO:0001578)
Microtubule cytoskeleton
(GO:0015630)
Microtubule organizing center
(GO:0005815)
Microtubule plus-end
(GO:0035371)
Microtubule plus-end binding
(GO:0051010)
Microtubule polymerization
(GO:0046785)
Mitotic spindle astral microtubule end
(GO:1905721)
Mitotic spindle pole
(GO:0097431)
Molecular adaptor activity
(GO:0060090)
Negative regulation of microtubule polymerization
(GO:0031115)
Non-motile cilium assembly
(GO:1905515)
Positive regulation of microtubule plus-end binding
(GO:1903033)
Positive regulation of microtubule polymerization
(GO:0031116)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein localization to astral microtubule
(GO:1902888)
Protein localization to centrosome
(GO:0071539)
Protein localization to microtubule
(GO:0035372)
Regulation of microtubule polymerization or depolymerization
(GO:0031110)
Spindle
(GO:0005819)
Spindle assembly
(GO:0051225)
Spindle midzone
(GO:0051233)

Other Information

Proteins

Microtubule-associated protein RP/EB family member 1

Genular Protein ID: 2011288164

Symbol: MARE1_MOUSE

Name: Microtubule-associated protein RP/EB family member 1

UniProtKB Accession Codes:

Q61166 Q7TN34

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15311282

Title: EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.

PubMed ID: 15311282

DOI: 10.1038/ncb1160

PubMed ID: 18854161

Title: ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.

PubMed ID: 18854161

DOI: 10.1016/j.cell.2008.07.045

PubMed ID: 19553473

Title: Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics.

PubMed ID: 19553473

DOI: 10.1091/mbc.e09-01-0009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21357749

Title: Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting.

PubMed ID: 21357749

DOI: 10.1083/jcb.201007113

PubMed ID: 21646404

Title: SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase.

PubMed ID: 21646404

DOI: 10.1083/jcb.201012179

PubMed ID: 23055941

Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

PubMed ID: 23055941

DOI: 10.1371/journal.pgen.1002969

PubMed ID: 24706950

Title: GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.

PubMed ID: 24706950

DOI: 10.1242/jcs.140558

PubMed ID: 30787442

Title: The centrosome protein AKNA regulates neurogenesis via microtubule organization.

PubMed ID: 30787442

DOI: 10.1038/s41586-019-0962-4

Sequence Information:

Length: 268
Mass: 30016
Checksum: 8FE3AFB7A5AE7762
Sequence:

MAVNVYSTSV TSDNLSRHDM LAWINESLQL NLTKIEQLCS GAAYCQFMDM LFPGSIALKK 
VKFQAKLEHE YIQNFKILQA GFKRMGVDKI IPVDKLVKGK FQDNFEFVQW FKKFFDANYD 
GKEYDPVAAR QGQETAVAPS LVAPALSKPK KPLGSSTAAP QRPIATQRTT AAPKAGPGMV 
RKNPGVGNGD DEAAELMQQV KVLKLTVEDL EKERDFYFGK LRNIELICQE NEGENDPVLQ 
RIVDILYATD EGFVIPDEGG PQEEQEEY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mapre1

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. PubMed ID: 15311282

ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. PubMed ID: 18854161

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics. PubMed ID: 19553473

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting. PubMed ID: 21357749

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. PubMed ID: 21646404

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PubMed ID: 23055941

GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins. PubMed ID: 24706950

The centrosome protein AKNA regulates neurogenesis via microtubule organization. PubMed ID: 30787442